A5100375799- High Altitude and Hypoxia
- Genetic diversity and population structure
- Electron Spin Resonance Studies
- Fish Ecology and Management Studies
- Physiological and biochemical adaptations
- Parasitic Infections and Diagnostics
- Isotope Analysis in Ecology
- Coccidia and coccidiosis research
- Fish Biology and Ecology Studies
- Plant Ecology and Soil Science
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Plant Diversity and Evolution
- Bioactive Compounds and Antitumor Agents
- Marine Bivalve and Aquaculture Studies
- Enzyme Structure and Function
- Genetic Mapping and Diversity in Plants and Animals
- Census and Population Estimation
- DNA and Nucleic Acid Chemistry
- Estrogen and related hormone effects
- Protein Structure and Dynamics
- Insurance, Mortality, Demography, Risk Management
- Enterobacteriaceae and Cronobacter Research
- Xenotransplantation and immune response
- CRISPR and Genetic Engineering
- Animal Genetics and Reproduction
Chinese Academy of Sciences
1999-2023
Sichuan University
2023
Institute of Zoology
2023
Kunming Institute of Zoology
2021-2022
Shaanxi University of Technology
2022
University of Chinese Academy of Sciences
2021
Lanzhou University
2021
Chinese Academy of Fishery Sciences
2015
Ministry of Agriculture and Rural Affairs
2015
Institute of Oceanology
2013-2014
The pen shell, Atrina pectinata, is one of the commercial bivalves in East Asia and thought to be recently affected by anthropogenic pressure (habitat destruction and/or fishing pressure). Information on its population genetic structure crucial for conservation A. pectinata. Considering long pelagic larval duration iteroparity with high fecundity, pectinata could expected weak at a fine scale. However, unusual oceanography coasts China Korea suggests potential restricted dispersal larvae...
Zokors in the genus Eospalax, which are endemic to northern and western China, subterranean rodents that inhabit various niches, including grasslands, high-altitude meadows, forests, farmlands. Six species Eospalax were described a century ago but their taxonomy phylogeny remain controversial. In this study, we performed high-depth whole-genome sequencing of 47 zokor samples, comprising all six previously species. Genomic analyses revealed reliable robust supported validity named According...
The evolutionary outcomes of high elevation adaptation have been extensively described. However, whether widely distributed endemic animals adopt uniform mechanisms during to different elevational environments remains unknown, especially with respect extreme environments. To explore this, we analysed the phenotypic and genomic data seven populations plateau zokor (Myospalax baileyi) along elevations ranging from 2,700 4,300 m. Based on whole-genome sequencing demographic reconstruction...
The correlation between altitude and metabolic syndrome has not been extensively studied, the mediation effects of diet physical activity remain unclear. We evaluated cross-sectional correlations possible in China.We included 89 485 participants from China Multi-Ethnic Cohort. extracted their information residential addresses determined if they had by presence three or more following components: abdominal obesity, reduced high-density lipoprotein cholesterol (HDL-C), elevated triglycerides,...
The Farnesoid X receptor (FXR) has recently become a potential therapeutical target. recruitment of coactivator protein (specified by LXXLL sequence) is the initial step in transcriptional activation nuclear receptors (NRs). In this paper, process recognition motif ligand binding domain (LBD) FXR observed 25 ns molecular dynamics simulation. hydrophobic and hydrogen bonding interactions between LBD are fully analyzed. This observation provides justification for 'on deck' model proposed...
The olfactory acuity of female mice allows them to discriminate the urinary odors males. Parasitic infection can reduce odor attractiveness male females and result in aversion or avoidance responses selection. However, chemical signaling changes pheromone contents produced by foreskin gland were not fully revealed after parasitic infection. Cryptosporidium parvum (C. parvum) is a common zoonotic intestinal parasite has wide range hosts, including human, domestic animals, wild animals. In...
A nuclear magnetic resonance (NMR) method for the precise determination of internuclear distances is proposed. This method, called two-field-NOESY or simply 2F-NOESY, based on fact that cross-relaxation rates between spins, which can be measured by Overhauser enhancement spectroscopy (NOESY), are intrinsically frequency dependent. The has advantage reorientational correlation times individual dipole–dipole vectors simultaneously determined along with distances.
When nuclear Overhauser enhancement spectroscopy (NOESY) experiments are performed around the critical point ωτc = 1.12, internuclear cross-relaxation rates dependent on resonance frequency ω, where τc is reorientation time of distance vector between two magnetic dipoles. Therefore, correlation times and, consequently, distances can be determined precisely by measuring under fields. An application with a cyclic pentapeptide given as an example, demonstrating use two-field NOESY method in...