A5071427190- Crystallization and Solubility Studies
- Metal complexes synthesis and properties
- X-ray Diffraction in Crystallography
- Synthesis and Characterization of Heterocyclic Compounds
- Ferrocene Chemistry and Applications
- Antimicrobial agents and applications
- Click Chemistry and Applications
- Organometallic Compounds Synthesis and Characterization
- Phenothiazines and Benzothiazines Synthesis and Activities
Medical University of Lodz
2018-2025
Hyperpigmentation can be prevented by regulating melanin synthesis through tyrosinase inhibition. As such, inhibitors like arbutin, kojic acid, and hydroquinone are commonly used for skin lightening. Recent studies suggest that certain pyrazole derivatives with activity may also have anticancer potential influencing melanocyte transformation tumor progression, positioning them as promising candidates both cosmetic therapeutic uses. The aim of this study was to evaluate the inhibitory...
Arene-ruthenium(II) complexes with carbothioamidopyrazoles at the C-2 and C-5 positions have been recognized as chemotherapeutic agent alternatives to cisplatin its oxaliplatin analogs. The aim of this study was continue research on biological aspect arene-ruthenium(II) their anticancer activity. present paper includes an additional 12 new tumor cells, analyzed by MTT, employs a series extended bioassays better understand potential mechanism antitumor following tests were conducted: membrane...
Ruthenium(ii) complexes are lately of great scientific interest due to their chemotherapeutic potential as anticancer and antimicrobial agents. Here we present the synthesis new pyrazole carbothioamide derivatives four arene-ruthenium complexes. The title compounds were characterized with application IR, NMR, mass spectrometry, elemental analysis X-ray diffraction. Additionally, for DFT calculations done. Their activity (MIC, MBC/MFC) was examined in vitro against Staphylococcus aureus,...
To meet the demand for alternatives to commonly used antibiotics, this paper evaluates antimicrobial potential of arene-ruthenium(II) complexes and their salts, which may be value in antibacterial treatment. Their activity (MIC, MBC/MFC) was examined vitro against