A5067576846- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Autism Spectrum Disorder Research
- Face Recognition and Perception
- Action Observation and Synchronization
- Multisensory perception and integration
- Neurobiology of Language and Bilingualism
- Neural and Behavioral Psychology Studies
- Memory and Neural Mechanisms
- Genetics and Neurodevelopmental Disorders
- EEG and Brain-Computer Interfaces
- Visual perception and processing mechanisms
- Biochemical Analysis and Sensing Techniques
- Advanced MRI Techniques and Applications
- Memory Processes and Influences
- Advanced Neuroimaging Techniques and Applications
- Olfactory and Sensory Function Studies
- Attention Deficit Hyperactivity Disorder
- Child and Animal Learning Development
- HIV Research and Treatment
- Neuroscience and Neuropharmacology Research
- Obsessive-Compulsive Spectrum Disorders
- Motor Control and Adaptation
- Virology and Viral Diseases
- Diet and metabolism studies
National Institute of Mental Health
2016-2025
National Institutes of Health
2015-2024
University of Pennsylvania
2023
University of Calgary
2022
National Institute of Mental Health
2019
McGovern Institute for Brain Research
2011
Newberry College
2010
Center for Autism and Related Disorders
2009
Children's National
2009
Université de Montréal
2009
Evidence from functional neuroimaging of the human brain indicates that information about salient properties an object-such as what it looks like, how moves, and is used-is stored in sensory motor systems active when was acquired. As a result, object concepts belonging to different categories like animals tools are represented partially distinct, sensory- property-based neural networks. This suggests not explicitly represented, but rather emerge weighted activity within regions. However,...
The areas of the brain that mediate knowledge about objects were investigated by measuring changes in regional cerebral blood flow (rCBF) using positron emission tomography (PET). Subjects generated words denoting colors and actions associated with static, achromatic line drawings one experiment, written names a second experiment. In both studies, generation color selectively activated region ventral temporal lobe just anterior to area involved perception color, whereas action middle gyrus...
Brain imaging and electrophysiological recording studies in humans have reported discrete cortical regions posterior ventral temporal cortex that respond preferentially to faces, buildings, letters. These findings suggest a category-specific anatomically segregated modular organization of the object vision pathway. Here we present data from functional MRI study which found three distinct responded faces two categories other objects, namely houses chairs, had highly consistent topological...
Resting-state functional magnetic resonance imaging (RS-FMRI) holds the promise of revealing brain connectivity without requiring specific tasks targeting particular systems. RS-FMRI is being used to find differences between populations even when a candidate target for traditional inferences lacking. However, problem with lacking definition what constitutes noise and signal. easy acquire but not analyze or draw from. In this commentary we discuss that still treated lightly despite its...
Increasing research indicates that concepts are represented as distributed circuits of property information across the brain's modality-specific areas. The current study examines representation an important but under-explored category, foods. Participants viewed pictures appetizing foods (along with locations for comparison) during event-related fMRI. Compared to location pictures, food activated right insula/operculum and left orbitofrontal cortex, both gustatory processing Food also...
We used fMRI to study the organization of brain responses different types complex visual motion. In a rapid event-related design, subjects viewed video clips humans performing whole-body motions, manmade manipulable objects (tools) moving with their characteristic natural motion, point-light displays human and objects. The lateral temporal cortex showed strong both videos displays, supporting hypothesis that is cortical locus for processing Within cortex, we observed segregated superior...
The hemispheric lateralization of certain faculties in the human brain has long been held to be beneficial for functioning. However, quantitative relationships between degree particular regions and level functioning have yet established. Here we demonstrate that two distinct forms functional are present left vs. right cerebral hemisphere, with hemisphere showing a preference interact more exclusively itself, particularly cortical involved language fine motor coordination. In contrast,...
Autism spectrum disorders are developmental characterized by impairments in social and communication abilities repetitive behaviours. Converging neuroscientific evidence has suggested that the neuropathology of autism is widely distributed, involving impaired connectivity throughout brain. Here, we evaluate hypothesis decreased high-functioning adolescents with an disorder relative to typically developing concentrated within domain-specific circuits specialized for processing. Using a novel...