A5070889419- Viral Infections and Outbreaks Research
- Viral Infections and Vectors
- Hepatitis B Virus Studies
- Bat Biology and Ecology Studies
- Animal Ecology and Behavior Studies
- Environmental and Biological Research in Conflict Zones
- Bacillus and Francisella bacterial research
- Genetic diversity and population structure
- Yersinia bacterium, plague, ectoparasites research
- Evolution and Paleontology Studies
- Mosquito-borne diseases and control
- Disaster Response and Management
- Chromosomal and Genetic Variations
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 diagnosis using AI
- Vaccine Coverage and Hesitancy
Obafemi Awolowo University
2015-2024
Federal Medical Centre
2016
Bernhard Nocht Institute for Tropical Medicine
2016
Benue State University
2016
Ambrose Alli University
2016
Irrua Specialist Teaching Hospital
2016
Public Health Foundation
2000
Lassa virus (LASV) causes a deadly haemorrhagic fever in humans, killing several thousand people West Africa annually. For 40 years, the Natal multimammate rat, Mastomys natalensis, has been assumed to be sole host of LASV. We found evidence that LASV is also hosted by other rodent species: African wood mouse Hylomyscus pamfi Nigeria, and Guinea erythroleucus both Nigeria Guinea. Virus strains from these animals were isolated BSL-4 laboratory fully sequenced. Phylogenetic analyses viral...
Lassa fever, killing thousands of people annually, is the most reported viral zoonotic disease in Nigeria. Recently, different rodent species carrying diverse lineages virus (LASV) addition to a novel Mobala-like genetic sequence were detected within country. Here, screening 906 small mammal specimens from 11 localities for IgG antibodies and incorporating previous PCR detection data involving same populations, we further describe arenavirus prevalence across Nigeria relation host...
Mastomys natalensis rodents are natural hosts for Lassa virus (LASV). Detection of LASV in 2 mitochondrial phylogroups the rodent near Niger and Benue Rivers Nigeria underlines potential emergence fresh this rodent. A Mobala-like sequence was also detected eastern Nigeria.
Nigeria has a rich small mammal community, with several species implicated as carriers of zoonotic microbes such the Lassa virus (LASV). We sought to elucidate diversity and distribution these animals (including known LASV reservoirs) geographically, habitat-wise seasonally. Our DNA-assisted survey detected at least 19 amongst 790 specimens. Diversity indices were similar between ecological zones also endemic non-endemic areas for fever. Mastomys natalensis, most renowned host, was present...
We phylogenetically compared sequences of the zoonotic Lassa virus (LASV) obtained from Mastomys rodents in seven localities across highly endemic Edo and Ondo States within Nigeria. Sequencing 1641 nt S segment genome, we resolved clades lineage II that were either limited to Ebudin Okhuesan state (2g-beta) or along Owo-Okeluse-Ifon (2g-gamma). also found Ekpoma, a relatively large cosmopolitan town state, extended into other (2g-alpha) (2g-delta). LASV variants M. natalensis Ekpoma State...
Abstract Bats are not only ecologically valuable mammals but also reservoirs of zoonotic pathogens. Their vast population, ability to fly, and inhabit diverse ecological niches could play some role in the spread antibiotic resistance. This study investigated non-aureus staphylococci Mammaliicoccus colonization Hipposideros bats at Obafemi Awolowo University, Ile-Ife, Nigeria. Pharyngeal samples ( n = 23) insectivorous were analyzed, presumptive staphylococcal isolates confirmed by...
The age-related mortality and morbidity risk of COVID-19 has been considered speculative without enough scientific evidence. This study aimed to collect more evidence on the association between patient age severe disease state and/or from SARS-CoV-2 infection. Genomic dataset along with metadata (3608 samples) retrieved GISAID different geographical regions were grouped into 10 groups (0-10, 11-20, 21-30, 31-40, 41-50, 51-60, 61-70, 71-80, 81-90, 91-100 years) as well high-risk or low-risk...