A5100698948- Insect Resistance and Genetics
- Plant Virus Research Studies
- Estrogen and related hormone effects
- Cancer, Lipids, and Metabolism
- RNA Research and Splicing
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Insect symbiosis and bacterial influences
- CRISPR and Genetic Engineering
- RNA Interference and Gene Delivery
- Plant-Microbe Interactions and Immunity
- Plant-based Medicinal Research
- Pleural and Pulmonary Diseases
- Axon Guidance and Neuronal Signaling
- Medicinal Plant Pharmacodynamics Research
- Respiratory Support and Mechanisms
- Legume Nitrogen Fixing Symbiosis
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Studies on Chitinases and Chitosanases
- Cardiovascular Disease and Adiposity
- Plant Molecular Biology Research
- Plant Disease Resistance and Genetics
- Angiogenesis and VEGF in Cancer
- Apelin-related biomedical research
Inner Mongolia University
2016-2021
Inner Mongolia People's Hospital
2019-2021
First Affiliated Hospital of Jiamusi University
2007-2011
Jiamusi University
2007-2011
RNAi (RNA interference) is a technology for silencing of target genes via sequence-specific manner. has been used development anti-pathogenic crops. In 2007, transgenic plants resistant to insect herbivore using was first reported, leading burst efforts aimed at exploitation mechanism and control strategy against variety species based on this technique. Mythimna separata belongs noctuidae family lepidoptera posing threat crops economic importance. Recently, outbreaks M. severely threatens...
Plants protect themselves from virus infections by several different defence mechanisms. RNA interference (RNAi) is one prominent antiviral mechanism, which requires the participation of AGO (Argonaute) and Dicer/DCL (Dicer-like) proteins. Effector-triggered immunity (ETI) an mechanism mediated resistance (R) genes, most encode nucleotide-binding site-leucine-rich repeat (NBS-LRR) family MicroRNAs (miRNAs) play important regulatory roles in plants, including regulation host defences. Soybean...
Soybean mosaic virus (SMV), which belongs to the Potyviridae, causes significant reductions in soybean yield and seed quality. In this study, both tag-free reporter gene green fluorescent protein (GFP)-containing infectious clones for SMV N1 strain were constructed by Gibson assembly with yeast homologous recombination system, respectively. Both are suitable agroinfiltration on model host N. benthamiana show strong infectivity natural several other legume species. transmitted caused typical...
Host-induced gene silencing (HIGS) emerged as a new strategy for pest control. However, RNAi efficiency is reported to be low in Lepidoptera, which are composed of many important crop pests. To address this, we generated transgenic plants develop HIGS effects maize pest, Mythimna separata (Lepidoptera, Noctuidae), by targeting chitinase encoding genes. More importantly, developed an artificial microRNA (amiR) based PTA (polycistronic-tRNA-amiR) system multiple target Compared with hpRNA...
Long non-coding RNAs (lncRNAs) have important roles in the development and progression of various types human cancer. However, expression function lncRNA prostate cancer-associated RNA 1 (PRNCR1) breast cancer remains unclear. Reverse transcription-quantitative PCR was performed to measure levels mRNA expression. Cell counting kit-8, flow cytometry, wound healing Transwell assays were also study cell proliferation, cycle, migration invasion, respectively. The results present revealed that...
MicroRNA (miRNA/miR)‑124 is widely accepted as the suppressor of different tumors. The present study aimed to improve understanding potential role miR‑124 in breast cancer. gene expression profile change derived from overexpression was investigated using RNA sequencing and bioinformatics analysis cancer cell line SKBR3. results demonstrated that SKBR3 cells significantly changed. In addition, transcription factor activating enhancer‑binding protein 4 (TFAP4) identified among top 10...
Objective To investigate the effect of tamoxifen (TAM) on invasiveness breast cancer SK-BR-3 cells and its mechanism. Methods The in logarithmic growth period were cultured for 24 h by theserum-free RPMI 1640 culture medium, then divided into control group (serum-free medium) TAM (serum-freeRPMI 16400.5, 2.5, 12.5 mol·L-1TAM) . Western blot was used to detect matrix metalloproteinase-9 (MMP-9) , metalloproteinase-2 (MMP-2) vascular endothelial factor (VEGF) groups. Scratch...