- Parasites and Host Interactions
- Wound Healing and Treatments
- Parasite Biology and Host Interactions
- Global Maternal and Child Health
- Pharmaceutical studies and practices
- Malaria Research and Control
- Pharmaceutical Economics and Policy
- Health Systems, Economic Evaluations, Quality of Life
- Bee Products Chemical Analysis
- Child Nutrition and Water Access
- Ethnobotanical and Medicinal Plants Studies
- Global Cancer Incidence and Screening
- Moringa oleifera research and applications
- Antimicrobial Peptides and Activities
- Anesthesia and Sedative Agents
- Food Science and Nutritional Studies
- Phytochemistry Medicinal Plant Applications
- Research on Leishmaniasis Studies
- Seed and Plant Biochemistry
- Burn Injury Management and Outcomes
- Parasitic Diseases Research and Treatment
- Insect Pest Control Strategies
- Complementary and Alternative Medicine Studies
- Epilepsy research and treatment
- Economic and Financial Impacts of Cancer
University of Zimbabwe
2015-2022
University of KwaZulu-Natal
2020-2021
Plants have arrays of phytoconstituents that wide ranging biological effects like antioxidant, anti-inflammatory and antimicrobial properties key in wound management. In vivo healing ointments made crude methanolic extracts (10% extract w/w white soft paraffin) three plant species, Cissus quadrangularis L. (whole aerial parts), Adenium multiflorum Klotzsch parts) Erythrina abyssinica Lam. Ex DC. (leaves bark) used ethnoveterinary medicine were evaluated on BALB/c female mice based area...
Traditional medicines are widely used in the rapidly growing health system and of economic importance. The study aimed at determining frequency, pattern use factors that influence traditional during pregnancy.A cross-sectional was carried out four district hospitals Manicaland, Zimbabwe, using questionnaire based convenience sampling.Traditional found to be high with 54% (n = 337) pregnant women pregnancy. major purpose medicine preparation for delivery; cervical dilation particular....
Herbal medicines are considered an intricate and integral part of humankind's knowledge systems. Time has proven their efficacy safety for both human animal applications. Modern science, guided by indigenous systems can further optimize the use various herbal products. To widen current focus on medicines, a study was carried-out to determine antioxidant properties, phytochemical mineral contents some medicinal plants used in ethnoveterinary practices management wounds Zimbabwe. The studied...
Knowledge gaps exist between host genetic factors and susceptibility to schistosomiasis.This study determined cytokine levels single nucleotide polymorphisms of tumour necrosis factor (TNF)-α (rs1800629) interleukin (IL)-10 (rs1800871) their possible impact on schistosomiasis in preschool-age children the Madziva area Shamva district, Mashonaland Central province, Zimbabwe.Urogenital was diagnosed using urine filtration method, while a sandwich enzyme-linked immunosorbent assay used for...
Host genetic factors can influence susceptibility, morbidity and mortality from schistosomiasis. The study explored the association between single nucleotide polymorphisms (SNPs) in interleukin-10 (IL-10) tumour necrosis factor alpha (TNF-α) promoter regions susceptibility to Schistosoma haematobium infection.Urine specimens were collected 361 primary school children aged 5-15 years schistosomiasis endemic areas of Manicaland Mashonaland central provinces. was diagnosed using urine...
Infection with Plasmodium falciparum parasites may result in a wide spectrum of symptoms ranging from asymptomatic to mild or severe. A number factors are associated this heterogeneous response P. infection. In the present study, associations sub-microscopic Schistosoma species and TNF (rs1800629) polymorphism were investigated.361 clinically healthy primary school children microscopically screened for S. haematobium, mansoni falciparum. Sub-microscopic infections determined by PCR....
Introduction: There is high malaria related morbidity and mortality amongst infants children in endemic areas. An In-depth understanding of protective immunity correlates enables the long due necessary development an effective vaccine. This study aimed at evaluating antibody responses to apical membrane antigen 1 (AMA 1) that helps P falciparum entry into red blood cells, Glutamate rich protein (GLURP), expressed whole life cycle causing pathogen, merozoite surface protein-1 (MSP coding for...
Water, methanol (MetOH) and ethanol (EtOH) extracts obtained from seeds roots of the red variety Sorghum bicolor (domesticated) arundinaceum (wild plant) were assayed for antibacterial, antifungal anti-inflammatory (COX- 1 COX-2) activities. The antibacterial activities evaluated using micro-dilution assays against a Gram- positive (Staphylococcus aureus), Gram-negative bacteria (Escherichia coli) fungus Candida albicans. Both MetOH EtOH (roots seeds) found to inhibit bacterial fungal...
Many of the cancer cases in Zimbabwe are HIV related, making it a significant health concern country. This requires innovative ways, such as implementing Value-Added Tax (VAT) to finance management through insurance. The study explores general public, patients, and public authorities' perception regarding using VAT system for financing treatment.A qualitative cross-sectional was conducted explore participants on 'Value Added Tax' source healthcare Harare. done use in-depth interview guides....