A5004783870- Nanoparticles: synthesis and applications
- Heavy Metal Exposure and Toxicity
- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Diet, Metabolism, and Disease
- Human Health and Disease
- Nutrition, Genetics, and Disease
- Biochemical effects in animals
- Regulation of Appetite and Obesity
- Sirtuins and Resveratrol in Medicine
- Trace Elements in Health
- Aluminum toxicity and tolerance in plants and animals
- Graphene and Nanomaterials Applications
- Advanced Cellulose Research Studies
- Liver Disease Diagnosis and Treatment
- Microplastics and Plastic Pollution
- Biochemical Analysis and Sensing Techniques
- Anesthesia and Neurotoxicity Research
- Adipokines, Inflammation, and Metabolic Diseases
- Carbon Nanotubes in Composites
- Therapeutic Uses of Natural Elements
- Peroxisome Proliferator-Activated Receptors
- Food composition and properties
- Curcumin's Biomedical Applications
- Medical and Agricultural Research Studies
Federal Research Centre of Nutrition and Biotechnology
2015-2024
Sechenov University
2022
Federal Scientific Center for Medical and Preventive Health Risk Management Technologies
2018
Hanoi National University of Education
2018
North-Eastern Federal University
2018
Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
2018
Russian Academy of Sciences
2007-2014
Academy of Medical Sciences
2013-2014
Silver nanoparticles (NPs), widely used in the manufacture of various types consumer products and for medical applications, belong to novel materials that pose potential risks human health. The negative effects influence these NPs on reproduction are insufficiently researched. A quantitative assessment transfer metallic silver through placenta breast milk was carried out during an vivo experiment. We 34.9 14.8 nm size were stabilized by low-molecularweight polyvinylpyrrolidone labeled with...
The methods for isolation and identification of nanoparticles quantitative determination in complex multicomponent mixed-phase systems are considered. These include most environmental objects, particular, animal plant organisms, agricultural raw materials, foodstuffs various sorts consumer goods. published data the results authors' research concerning types biological samples by electron microscopy, chromatography radioactive tracer method generalized. bibliography includes 161 references.
Amino acids tyrosine (Tyr) and tryptophan (Trp) play a significant role in the regulation of energy metabolism, locomotor activity, eating behavior. We studied possibility modulating these processes obesity by increasing pool Tyr Trp experimental diet. As model obesity, we used Wistar rats fed diet with an excess specific value (HFCD) for 64 days. led to normalization rats’ body weight almost control level, but increased anxiety-like behavior decreased long-term memory. The consumption amino...
Bacterial nanocellulose (BNC) is being considered as a potential replacement for microcrystalline cellulose food additive and source of dietary fiber due to its unique properties. However, studies on the risks consuming BNC in are limited, it not yet approved use US, EU, Russia. Aim: This study aims perform toxicological hygienic assessment safety subacute 8-week administration rats. Methods: was administered male Wistar rats doses 0, 1.0, 10.0, 100 mg/kg body weight 8 weeks. Various...
We compared anxiety, neuromotor, and cognitive functions in mutant rats with different allelic variants of dopamine transporter DAT knockout receiving balanced or excess fat fructose diet. The experiments were performed DAT−/− homozygotes, DAT+/− heterozygotes, DAT+/+ wild type rats. genotype DAT-KO was confirmed by restriction analysis gene to behavioral responses the open field test (OF). Animals first groups each strain fed a AIN93M diet; those second high-fat/high-fructose Neuromotor...
The experimental data on the oral toxicity of nanostructured amorphous silica (SiO2), widely used in food supplements, pharmaceuticals, and cosmetics, terms its vivo effect immune system, are contradictory. Therefore, this study aimed to assess rat's function after SiO2 administration. In first experiment, was daily orally administered Wistar rats for 92 days doses 0.1, 1.0, 10, 100 mg/kg body weight (bw). second 28-day a dose bw parenterally immunized with allergen ovalbumin (OVA)...
We studied the effects of addition large neutral amino acids, such as tyrosine (Tyr) and tryptophan (Trp), in mice DBA/2J tetrahybrid DBCB receiving a high-fat, high-carbohydrate diet (HFCD) for 65 days. The locomotor activity, anxiety, muscle tone, mass internal organs, liver morphology, adipokines, cytokines, biochemical indices animals were assessed. Tyr supplementation potentiated increased anxiety EPM contributed to tone increase, decrease AST/ALT ratio, an increase protein anabolism...
The development of innovative ingredients specialized formula for children with intolerance to cow's milk proteins requires accounting the influence protein component on allergic sensitivity.
Nanoclays (NC) are aluminosilicates that consist of layers (nano-plates) being 1-2 nanometers thick and having a diameter over 1 µm, nanotubes, nano-disks.Due to such structure their ion-exchange sorption properties as well gas permeability NC widely used in industries, agriculture, medicine.Gas-barrier composite packages made from hydrophobic modified with cation-active surface-active substances.A person can be orally exposed due migration into food products drinks, when applied medicine...
Using of silver nanoparticles in consumer goods and medicine gives big benefits, but there is also the problem their toxicity for health environment. There a lot literature on experiments with absorption, biodistribution, metabolism excretion (ADME) living organisms, low information exists yet accumulation various biological organs mammals. Previous have indicated clearance from organs, which histochematic barriers, e.g brain, testes. This article reports results three month experiment daily...
Nickel (Ni) nanoparticles (NPs) are used as technological aids-catalysts in the oil and fat industry, pharmaceuticals, production of cosmetics pesticides. The acute subchronic oral toxicity metallic Ni nanoform is not well understood. study aimed to investigate NPs rats. We two NP preparations (Ni NP1 NP2) with spherical particles an average diameter 53.7 70.9 nm according electron microscopy data. In toxicity, both kinds were administered male female Wistar rats aged 8 weeks a single dose...
Nanomaterials (NMs) are applied in many spheres related to food products manufacturing including nanodispersed forms of substances, nano-encapsulates, and nano-micelles, additives with improved functional characteristics, new packaging materials enhanced gas-, photobarrier, antimicrobic properties.High chemical catalytic activity nanoparticles (NPs) their ability penetrate through biological barriers accumulate a body makes lot NMs toxic, toxic properties be taken into account when assessing...
Nanocelluloses (NCs) have broad application prospects in medicine as implants, cell scaffolds and dressings, the production of composite materials coatings, electronics, food pharmaceutical products. The main types NCs include nanofibrous (NFC), nanocrystalline (NCC) cellulose isolated from natural, predominantly plant materials, bacterial nanocellulose (BNC) obtained by microbial synthesis. process NC can many factors potent affecting their toxicological characteristics, such residual...