A5102975904- Microbial Inactivation Methods
- Plasma Applications and Diagnostics
- Immunotherapy and Immune Responses
- CAR-T cell therapy research
- Epigenetics and DNA Methylation
- Toxin Mechanisms and Immunotoxins
- Pancreatic and Hepatic Oncology Research
- Electrostatic Discharge in Electronics
- Cancer Immunotherapy and Biomarkers
- Cancer, Hypoxia, and Metabolism
- Pulmonary Hypertension Research and Treatments
- Cancer, Stress, Anesthesia, and Immune Response
- Tracheal and airway disorders
- Vascular Anomalies and Treatments
University of Tennessee Health Science Center
2022-2024
University of Minnesota
2019-2022
University of Minnesota Medical Center
2019-2020
Memory CD8+ T cells populate non-lymphoid tissues (NLTs) following pathogen infection, but little is known about the establishment of endogenous tumor-specific tissue-resident memory (T
Abstract Boosting the response rate of immune checkpoint blockade (ICB) therapy to improve treatment efficacy is a primary goal in cancer immunotherapy. One promising approaches involves focal tumor ablation reduce burden and trigger situ vaccination. Even though this combination strategy has demonstrated enhanced therapeutic outcomes both preclinical research clinical trials, limited comparatively investigated diverse techniques. The optimal choice among techniques remains largely unknown....
Abstract Memory CD8+ T cells populate non-lymphoid tissues (NLT) and can protect against malignancies, but little is known about the establishment of tumor-specific tissue resident memory (TRM) by therapeutically initiated immune responses. We used a transplantable mouse model prostate carcinoma MHCI tetramers to track quantify cells. Tumor challenge led systemic expansion endogenous, naïve tumor antigen-specific established small population TRM (CD44hi, CD62Llo, CD69+, CD103+) in several...