A5017348956- Hepatitis B Virus Studies
- Health, psychology, and well-being
- Counseling Practices and Supervision
- Immunotherapy and Immune Responses
- Cell death mechanisms and regulation
- Psychological Well-being and Life Satisfaction
- Educational and Psychological Assessments
- Health disparities and outcomes
- T-cell and B-cell Immunology
- Collaborative Teaching and Inclusion
- RNA Interference and Gene Delivery
- Counseling, Therapy, and Family Dynamics
- Epigenetics and DNA Methylation
- Mycobacterium research and diagnosis
- Biomarkers in Disease Mechanisms
- Appendicitis Diagnosis and Management
- Minimally Invasive Surgical Techniques
- Immune Cell Function and Interaction
- Inflammasome and immune disorders
- Vibrio bacteria research studies
- Evaluation and Performance Assessment
- Tuberculosis Research and Epidemiology
- Phagocytosis and Immune Regulation
- Optimism, Hope, and Well-being
- Gallbladder and Bile Duct Disorders
Walter and Eliza Hall Institute of Medical Research
2017-2023
The University of Melbourne
2017-2022
Emory University
2012
Iowa State University
2003-2005
Counseling Center
1999-2003
University of Utah
1999
Central Washington University
1999
University of Nebraska–Lincoln
1999
The clinical and positive psychology usefulness of quality life, well-being, life satisfaction assessments depends on their ability to predict important outcomes detect intervention-related change. These issues were explored in the context a program instrument validation for Quality Life Inventory (QOLI) involving 3,927 clients from various settings. Clinical norms also generated that supplement existing nationwide norms. predictive validity QOLI university counseling center was supported...
A brief mock counseling session was potentially more risky but potent than a videotaped as an intervention for increasing self‐efficacy in prepractica trainees.
Targeting the potent immunosuppressive properties of FOXP3 + regulatory T cells (T regs ) has substantial therapeutic potential for treating autoimmune and inflammatory diseases. Yet, molecular mechanisms controlling reg homeostasis, particularly during inflammation, remain unclear. We report that caspase-8 is a central regulator homeostasis in context-specific manner decisive immune responses. In mouse genetic models, targeting led to accumulation effector resistant apoptotic cell death....
Abstract Necroptosis is a lytic and inflammatory form of cell death that highly constrained to mitigate detrimental collateral tissue damage impaired immunity. These constraints make it difficult define the relevance necroptosis in diseases such as chronic persistent viral infections within individual organ systems. The role necroptotic signalling further complicated because proteins essential this pathway, receptor interacting protein kinase 3 (RIPK3) mixed lineage domain-like (MLKL), have...
Caspase-8 transduces signals from death receptor ligands, such as tumor necrosis factor, to drive potent responses including inflammation, cell proliferation or death. This is a developmentally essential function because in utero deletion of endothelial causes systemic circulatory collapse during embryogenesis. Whether also required for cardiovascular patency adulthood was unknown. To address this question, we used an inducible Cre recombinase system delete Casp8 6-week-old conditionally...
A major unmet clinical need is a therapeutic capable of removing hepatitis B virus (HBV) genome from the liver infected individuals to reduce their risk developing cancer. strategy deliver such therapy could utilize ability target and promote apoptosis hepatocytes. Presently there no clinically relevant that has been shown effectively remove persistent episomal covalently closed circular HBV DNA (cccDNA) nucleus We used linearized single length various genotypes establish cccDNA-like...
This single-subject study presents the development of an observational rating scale supervision feedback. Feedback statements (N = 199) across 31 hours were scored on a 4-point for 4 behaviors: positivity, negativity, constructiveness, and specificity. Adequate interrater reliability initial estimates construct validity are provided.