A5032661944- SARS-CoV-2 detection and testing
- COVID-19 diagnosis using AI
- Salmonella and Campylobacter epidemiology
- COVID-19 Clinical Research Studies
- Biosensors and Analytical Detection
- Antibiotic Use and Resistance
- Animal Virus Infections Studies
- Pharmaceutical studies and practices
- Viral gastroenteritis research and epidemiology
- Pharmaceutical Practices and Patient Outcomes
- Recycling and utilization of industrial and municipal waste in materials production
- Cell Adhesion Molecules Research
- Force Microscopy Techniques and Applications
- Biochemical and Structural Characterization
- Viral Infections and Immunology Research
- Respiratory viral infections research
- Antibiotics Pharmacokinetics and Efficacy
- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Metallurgy and Material Science
- Health Systems, Economic Evaluations, Quality of Life
- Mining and Gasification Technologies
- Humic Substances and Bio-Organic Studies
University of Toledo
2022-2024
Emory University
2020-2023
The Ohio State University
2019
Waseda University
2000
As COVID-19 continues to spread globally, monitoring the disease at different scales is critical support public health decision making. Surveillance for SARS-CoV-2 RNA in wastewater can supplement surveillance based on diagnostic testing. In this paper, we report results of wastewater-based Emory University campus that included routine sampling sewage from a hospital building, an isolation/quarantine and 21 student residence halls between July 13th, 2020 March 14th, 2021. We examined...
ABSTRACT SARS-CoV-2 is a respiratory virus but it also detected in significant proportion of fecal samples COVID-19 cases. Recent studies have shown that wastewater surveillance can be low-cost tool for management pandemic and tracking outbreaks communities most been focusing on sampling from treatment plants. Institutional level may serve well early warning purposes since cases tracked immediate action executed the event positive signal. In this study, novel Moore swab method was developed...
Enteric fever is a severe systemic infection caused by Salmonella enterica serovar Typhi (ST) and Paratyphi A (SPA). Detection of ST SPA in wastewater can be used as surveillance strategy to determine burden identify priority areas for water, sanitation, hygiene interventions vaccination campaigns. However, sensitive specific detection environmental samples has been challenging. In this study, we developed validated two methods concentrating detecting ST/SPA from wastewater: the Moore swab...
Abstract Fibronectin-binding protein A (FnBPA), a displayed on the outer surface of Staphylococcus aureus , has structured A-domain that binds fibrinogen (Fg) and disordered repeat-region fibronectin (Fn). Amino acid substitutions in Fn-binding repeats (FnBRs) have previously been linked to cardiovascular infection humans. Here we used microtiter atomic force microscopy (AFM) investigate adhesion by variants full-length FnBPA covalently anchored cell wall Lactococcus lactis Gram-positive...
Background: Outpatient parenteral antibiotic therapy (OPAT) enhances patient safety, improves outcomes, and reduces healthcare costs by decreasing 30-day readmissions adverse events. However, the optimal structure follow-up protocols for OPAT programs remain undefined. Identifying high-risk patients readmission managing drug events (ADEs) are critical components of care. Objectives: This study aimed to evaluate impact a dedicated clinic on hospital readmissions, quantified administrative...
Background: Noroviruses (NoVs) are a leading cause of non-bacterial gastroenteritis in young children and adults worldwide. Snow Mountain Virus (SMV) is the prototype NoV GII genotype 2 (GII.2) that has been developed as viral model for human challenge studies, an important tool studying pathogenesis immune response infections evaluating vaccine candidates. Previous studies have identified blockade antibodies block binding virus-like particles (VLPs) to histo-blood group antigens (HBGAs)...
Abstract Enteric fever is a severe systemic infection caused by Salmonella enterica serovar Typhi (ST) and Paratyphi A (SPA). Detection of ST SPA in wastewater can be used as surveillance strategy to determine burden identify priority areas for water, sanitation, hygiene interventions vaccination campaigns. However, sensitive specific detection environmental samples has been challenging. In this study, we developed validated two methods concentrating detecting ST/SPA from wastewater: the...
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Abstract Background Noroviruses (NoVs) are a leading cause of non-bacterial gastroenteritis in young children and adults worldwide. Snow Mountain Virus (SMV) is the prototype NoV GII genotype 2 (GII.2) that has been developed as viral model for human challenge models, an important tool studying pathogenesis immune response infections evaluating vaccine candidates. Previous studies have identified blockade antibodies block binding virus-like particles (VLPs) to histo-blood group antigens...
Translation: The University of Toledo Journal Medical Sciences is the online journal launched by Toledo. Manuscripts will be considered on understanding that they report original work and are not under consideration for publication any other journal. publishes articles reporting experimental results basic or clinical research, case reports, reviews. uses a single blind peer review system each manuscript, based presented in its submission, evaluated two student reviewers one faculty reviewer....
Reduction of Greenhouse Gas Emissions through the Use Sewage Sludge as Fuel at Power PlantsThe main object this paper is to verify greenhouse gas reduction effects obtained by using biosolid fuel an alternative in coal-use plants. The various physical properties produced from four kinds solid-fuelizing systems were analyzed, and its examined. was then mixed with coal, burning test carried out a...Author(s)Makoto TerunumaHakuei YamamotoYasuhiro HashimotoYasumasa HoriMakoto...
Abstract Background Antibiotic stewardship has been a central challenge of the COVID-19 pandemic. Empiric antibiotic therapy is offered in 56.6%-74.6% inpatients with COVID-19, microbiologically confirmed bacterial pneumonia reported only 3.5%-16% cases. Procalcitonin (PCT) as biomarker for infection interest improving use. PCT-guided initiatives have demonstrated reduction use antibiotics An Infectious Diseases (ID) consultation was obtained on most patients at our institution throughout We...