A5044869039- Genetic and Kidney Cyst Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Otolaryngology and Infectious Diseases
- Kawasaki Disease and Coronary Complications
- Streptococcal Infections and Treatments
- Infective Endocarditis Diagnosis and Management
- Infectious Encephalopathies and Encephalitis
- Vascular Procedures and Complications
- Long-Term Effects of COVID-19
- Vascular anomalies and interventions
- Vasculitis and related conditions
- Renal Diseases and Glomerulopathies
- Indoor Air Quality and Microbial Exposure
- Vector-Borne Animal Diseases
- Dialysis and Renal Disease Management
- Gestational Trophoblastic Disease Studies
- Radiopharmaceutical Chemistry and Applications
- Leptospirosis research and findings
- Multiple Sclerosis Research Studies
- Pneumonia and Respiratory Infections
- Central Venous Catheters and Hemodialysis
- Thyroid Disorders and Treatments
- Gastrointestinal Tumor Research and Treatment
- Water Treatment and Disinfection
- Nerve injury and regeneration
Children's Medical Center
2024
Tokyo Metropolitan Children's Medical Center
2017-2018
The efficacy and safety of rituximab in childhood steroid-resistant nephrotic syndrome (SRNS) remains unclear. Therefore, we conducted a retrospective cohort study at 28 pediatric nephrology centers from 19 countries Asia, Europe, North America Oceania to evaluate this. Children with SRNS treated were analyzed according the duration calcineurin inhibitors (CNIs) treatment before [6 months or more (CNI-resistant) under 6 months]. Primary outcome was complete/partial remission (CR/PR) as...
Leptospirosis is considered underdiagnosed because of its nonspecific presentation and lack proper understanding epidemiology. Early diagnosis treatment are crucial. However, few data available on confirmed leptospirosis cases in children industrialized countries. We therefore aimed to describe epidemiologic clinical characteristics laboratory-confirmed childhood Okinawa, Japan. reviewed the national surveillance pediatric Japan from January 2003 through December 2015. The database included...
A 1-month-old girl developed respiratory failure due to bilateral interstitial pneumonia after bathing in reheated and reused water. molecular test for sputum an environmental culture detected Legionella pneumophila serotype 1. This is the first report of infantile legionellosis contracted from a bathtub at home.
The authors declare no conflict of interest.
In children, the causes of cerebral infarction are varied, and accurate diagnosis treatment imperative. An early school-age boy was brought to our hospital due seizures impaired consciousness. He diagnosed with primary central nervous system vasculitis (PCNSV) based on increased inflammatory response circumferential vessel wall thickening in his right middle artery. As neurological abnormalities had already improved at time diagnosis, he administered conservative without worsening. This is...
Abstract Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is an syndrome that develops during the febrile phase of infection characterized by bright tree appearance (BTA) on imaging. In this study, we examined a 1-year-old child who was diagnosed AESD caused severe acute respiratory coronavirus 2 (SARS-CoV-2) infection. He had fever for days disease 2019 day consultation based positive antigen test SARS-CoV-2. The stopped arrival to hospital; however, symptoms...
Abstract Objectives In consumptive hypothyroidism associated with infantile hepatic hemangiomas (IHH), elevated reverse triiodothyronine (rT3) is known due to D3. This report shows that rT3 a new indicator of IHH progression and three divided doses LT3 per day were more effective than single dose. Case presentation A 23 day-old boy was diagnosed diffuse severe high rT3. Propranolol LT4 administered. Hemangiomas gradually diminished decreased, but the thyroid-stimulating hormone remained...
There are three major therapeutic options for the treatment of Graves' disease (GD): antithyroid drugs (ATDs), thyroidectomy, and radio-iodine (RAI) therapy. ATDs initial option children. However, some pediatric GD patients who initially treated with require other type treatments later on. We reviewed medical records childhood-onset cases retrospectively to report clinical course received either surgery or RAI therapy subsequent ATDs. Childhood-onset was successfully managed in five girls...
CASE A previously healthy 13-year-old girl visited the emergency department with chief complaints of fever persisting for 7 days, headache, malaise and a rash. Her remained above 38 °C even after administration acetaminophen. No other medications were used. She had not traveled outside her area denied insect bites. At time visit, patient’s vital signs as follows: temperature 39.7 °C, heart rate 131 beats/min, blood pressure 113/67 mm Hg, respiratory 36 breaths/min oxygen saturation 96% (in...
A toddler girl was diagnosed with intra-abdominal simple cyst in the splenic flexure at gestational period. Due to a severe fever that persisted for 6 days, she admitted emergency room. The diagnosis of intraperitoneal infection made after contrast-enhanced CT revealed an enlarged and heterogeneous contrast effect on wall. double-wall sign observed wall during continuous ultrasound follow-up, which led preoperative as duplication cyst. peristalsis were identified via successive examinations...
A critical role in cellular proliferation is played by Casitas B-lineage Lymphoma proto-oncogene (CBL). Germline heterozygous CBL variants give rise to syndrome, which phenotypically similar RASopathy. Somatic mutations have been reported patients with juvenile myelomonocytic leukemia (JMML).Exome analysis was performed a patient immunodeficiency who developed Pneumocystis jirovecii pneumonia.Exome identified homozygous missense variant. Cell biological of this variant confirmed attenuated...