A5058033157- Renal Diseases and Glomerulopathies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Pediatric Urology and Nephrology Studies
- Pregnancy and Medication Impact
- Vitamin D Research Studies
- Urological Disorders and Treatments
- Renal and related cancers
- Urinary Tract Infections Management
- Adolescent and Pediatric Healthcare
- Electrolyte and hormonal disorders
- Complement system in diseases
- Erythrocyte Function and Pathophysiology
- Autoimmune Bullous Skin Diseases
- Vasculitis and related conditions
- Endometriosis Research and Treatment
- Blood groups and transfusion
- Urinary Bladder and Prostate Research
- Systemic Lupus Erythematosus Research
- Kidney Stones and Urolithiasis Treatments
- Global Maternal and Child Health
- Biomedical Research and Pathophysiology
- Autoimmune and Inflammatory Disorders Research
- Dialysis and Renal Disease Management
- Hormonal Regulation and Hypertension
- Chronic Kidney Disease and Diabetes
Institute of Child Health
2013-2024
Medical College and Hospital, Kolkata
2002-2024
AMRI Hospitals
2016
Children's Center
2001-2003
The efficacy and safety of rituximab in childhood steroid-resistant nephrotic syndrome (SRNS) remains unclear. Therefore, we conducted a retrospective cohort study at 28 pediatric nephrology centers from 19 countries Asia, Europe, North America Oceania to evaluate this. Children with SRNS treated were analyzed according the duration calcineurin inhibitors (CNIs) treatment before [6 months or more (CNI-resistant) under 6 months]. Primary outcome was complete/partial remission (CR/PR) as...
Childhood nephrotic syndrome (NS) is characterized by proteinuria, hypoalbuminemia, hypercholesterolemia, and edema. Approximately 10% to 15% of the patients do not achieve complete remission even after 4 6 weeks corticosteroid therapy are termed as having steroid-resistant NS (SRNS).S1 Up 30% children with SRNS may have underlying monogenic etiologies high risk progressing end-stage kidney disease, yet often paradoxically protective against disease recurrence postkidney transplant.1Sadowski...
<b><i>Background:</i></b> There is a paucity of information on epidemiology, diagnosis, and treatment outcomes congenital nephrotic syndrome (CNS) in developing countries. <b><i>Methods:</i></b> Retrospective (2012–2017) review case records undertaken across 12 Indian pediatric nephrology centers. <b><i>Results:</i></b> Sixty-five children (58% male, median birth weight 2.4 kg [interquartile range (IQR) 2.1–2.86]) were...
Congenital anomalies of the kidney and urinary tract (CAKUT) are predominant cause chronic disease (CKD) need for replacement therapy (KRT) in children. Although more than 60 genes known to CAKUT if mutated, genetic etiology is detected, on average, only 16% unselected cases, making testing unproductive.Whole exome sequencing (WES) was performed 100 patients with diagnosed first 1000 days life CKD stages 1 5D/T. Variants 58 established CAKUT-associated were extracted, classified according...
Among children with nephrotic syndrome, 10% to 15% are steroid resistant (steroid-resistant syndrome [SRNS]), and of these 30% may develop refractory SRNS that is nonresponsive the first-choice immunosuppressant for (i.e., calcineurin inhibitors [CNIs]).1Trautmann A. Vivarelli M. Samuel S. et al.IPNA clinical practice recommendations diagnosis management steroid-resistant syndrome.Pediatr Nephrol. 2020; 35: 1529-1561Crossref PubMed Scopus (22) Google Scholar These carry a guarded prognosis...