A5087824197- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Blood Pressure and Hypertension Studies
- Urinary Tract Infections Management
- Renal Diseases and Glomerulopathies
- Pediatric Urology and Nephrology Studies
- Neurological Disorders and Treatments
- Health and Conflict Studies
- Healthcare Systems and Public Health
- Renal and Vascular Pathologies
- Electrolyte and hormonal disorders
- Organ Donation and Transplantation
- Sodium Intake and Health
- Global Health Care Issues
- Muscle and Compartmental Disorders
- COVID-19 Clinical Research Studies
- Gout, Hyperuricemia, Uric Acid
- Adolescent and Pediatric Healthcare
- Hormonal Regulation and Hypertension
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Apelin-related biomedical research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Human Health and Disease
- Kidney Stones and Urolithiasis Treatments
- Pharmacological Effects of Natural Compounds
Shupyk National Healthcare University of Ukraine
2016-2025
Bogomolets National Medical University
2023-2025
Kiyv Municipal Medical College
2024
Emma Kinderziekenhuis
2024
European Institute of Oncology
2024
ORCID
2019
Kyiv City Clinical Oncology Center
2015
Bentham Science Publishers (United Arab Emirates)
2014
Bentham Science Publishers (China)
2014
National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”
2012
The efficacy and safety of rituximab in childhood steroid-resistant nephrotic syndrome (SRNS) remains unclear. Therefore, we conducted a retrospective cohort study at 28 pediatric nephrology centers from 19 countries Asia, Europe, North America Oceania to evaluate this. Children with SRNS treated were analyzed according the duration calcineurin inhibitors (CNIs) treatment before [6 months or more (CNI-resistant) under 6 months]. Primary outcome was complete/partial remission (CR/PR) as...
Background. All over the world, chronic kidney disease (CKD) is a global problem. Prevention of CKD development, as well rapid progression CKD, are priority tasks modern nephrology. A decrease in estimated glomerular filtration rate (eGFR) more than 5 ml/min/1.73 m2/year considered CKD. The purpose study was to assess risk patients with stage 1–3 by determining urinary albumin (uAlb)/urinary uromodulin (uUmod) ratio and comparing obtained results eGFR Charlson Comorbidity Index (CCI) these...
During conflicts, people with kidney disease, either those remaining in the affected zones or who are displaced, may be exposed to additional threats because of medical and logistical challenges. Acute injury developing on battlefield, field hospitals higher-level hospital settings is characterized by poor outcomes. People chronic disease experience treatment interruptions, contributing worsening function. Patients living dialysis a functioning graft limitations possibilities availability...
People living with kidney disease are among the most vulnerable at times of natural or man-made disasters. In addition to their unpredictable course, armed conflicts impose a major threat given disruption infrastructure, sanitation and access food, water medical care. The ongoing war in Ukraine has once more demonstrated importance preparedness, organization, coordination solidarity during face serious challenges dependence on life-sustaining treatment, irrespective whether they remain zone...
Due to the Russian-Ukrainian war, some of about 10 000 adults requiring dialysis in Ukraine fled their country continue abroad. To better understand needs conflict-affected patients, Renal Disaster Relief Task Force European Association conducted a survey on distribution, preparedness and management who were displaced due war.A cross-sectional online was sent via National Nephrology Societies across Europe disseminated centers. Fresenius Medical Care shared set aggregated data.Data received...
1Bogomolets Medical University, Kyiv, Ukraine This is an open access article distributed under the terms of Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it permissible to download and share work provided properly cited. The cannot be changed in any way or used commercially without permission from journal.
У статті наведено аналіз теоретичних і практичних результатів досліджень щодо вивчення проблеми ведення вагітності у жінок із наявною хронічною хворобою нирок (ХХН), оцінки потенційних проблем та факторів ризику розвитку ускладнень під час перебігу на тлі нефрологічної патології. приділяється увага питанням застосування ниркової замісної терапії вагітних жінок.
The article presents an analysis of theoretical and practical results research in PubMed, MEDLINE, Embase, Scopus Web Science databases on the study vitamin D metabolism its role development mineral bone disorders children with chronic kidney disease, assessment potential nutritional needs risk factors for complications background nephrological pathology. focuses use renal replacement therapy pediatric patients.
Glomerulonephritis is one of the most common kidney diseases in children, which leads to development chronic disease, failure, and early disability. According statistical data (2022), glomerulonephritis second among acquired childhood after urinary tract infections Ukraine. The system standardization medical care focused on implementation technological documents that help a doctor act effectively specific clinical situations, avoiding ineffective actions interventions. article considers...
This study evaluates the effectiveness of combination antiviral therapy for COVID-19 using Umifenovir and Oseltamivir compared with standard treatment. A total 85 outpatients confirmed were randomly assigned to two groups: 43 patients received (Umifenovir 200 mg 4 times daily, 75 twice daily 7 days), 42 based on WHO recommendations. The spanned 16 months. Primary endpoints included number
Background: Steroid-resistant nephrotic syndrome (SRNS) in adults presents a significant therapeutic challenge, often leading to end-stage kidneys. This study aims evaluate the clinical outcomes of rituximab (RTX) administration as an alternative traditional cytostatic therapy with SRNS, focusing on its effectiveness and safety profile. Methods: multicenter, randomized evaluates effects RTX for SRNS treatment, analyzing outcomes, safety, efficacy across 52 (median age 47, 52% male) over 36...
The paper discusses the development of chronic kidney disease (CKD). It is postulated that acute injury (AKI) may be onset CKD formation. pathogenesis transition to based on restriction sodium reabsorption in tubules, stimulation intrarenal renin-angiotensin system and blood flow nephron. authors express opinion practical aspect this mechanism correction hyponatremia, which leads restoration normal supply Thus, iatrogenic chloride diet AKI patients erroneous. present pathogenetic stages from...
Background. The ongoing conflict in Ukraine has disrupted the educational landscape, displacing students, teachers, and families while threatening continuity of learning across country. Amidst instability war, Ukrainian schools have demonstrated remarkable resilience, adapting pedagogical approaches redefining meaning education under crisis. Purpose. This study explores how educators students experience respond to displacement, loss, war-affected regions Ukraine. Using a qualitative...
BackgroundAnaemia is a common and potentially treatable co-morbidity of end-stage renal disease. We aimed to determine the prevalence sub-target haemoglobin (Hb) level among European children on dialysis identify factors associated with low Hb level.
Background. The purpose of this study was to assess the quality life (QoL) in patients with pre-dialysis chronic kidney disease (CKD), reveal factors affecting QoL category and investigate effect antioxidant therapy on CKD stages 1–5. Materials methods. Patients (n = 61), whose average age 44.51 ± 11.90 years, were included study. Twenty (32.79 %) men 41 (67.21 women divided into two groups representative terms gender composition: group 1 31) — who took glutathione 100 mg 2 times a day meals...
Kidney diseases, starting from acute kidney injury, disease, or having an uncertain onset, often progress to chronic disease (CKD). The pathomorphosis of this progression typically involves predominant damage the glomerulus, affecting either glomerular filter tubules, primarily in proximal part. International guidelines identify two key indicators for determining prognosis and CKD: albuminuria filtration rate. Additional criteria, such as blood pressure, pathomorphological changes,...
Steroid-sensitive nephrotic syndrome (SSNS) and steroid-resistant (SRNS) significantly affect children's quality of life. There are frequent relapses in SSNS progression SRNS. IPNA guidelines suggest that monoclonal antibodies like rituximab (RTX) promising treatments.
Abstract Background Despite of increasing prevalence bacterial resistance to antibiotics and possible adverse drug reactions (ADRs), uncomplicated lower urinary tract infections (uUTIs) are usually treated with antibiotics. Canephron® N, a herbal medicinal product, was now investigated for safety efficacy in women suffering from uUTI. Methods In an open-label, non-randomized, multicentre clinical trial 125 Caucasian female patients uUTI sum score at least 6 the symptoms dysuria, frequency...
Oxidative stress is a phenomenon caused by an imbalance of peroxide homeostasis. The concept oxidative was introduced in 1985 and has clear connection with redox chemistry. article provides detailed description molecular switches that control the response to stress. Four levels protection cell enzymatic antioxidants from action reactive oxygen species are described. It been shown antioxidant enzymes play major role rather than low weight compounds. stages lipid peroxidation considered. plays...
The paper considers the features of provision pediatric and adult nephrology medical care during martial law in Ukraine from February 2022 to May 2023. influence military stages on are presented, territorial zones conflict highlighted, event tracks shown. Separately, activity Ukrainian Association Nephrologists/Ukrainian Pediatric Nephrologists, new opportunities for integrating into system knowledge considered. Along with negative trends, positive results were revealed that made it possible...