Augustina Jankauskienė
A5057757061- Dialysis and Renal Disease Management
- Renal Diseases and Glomerulopathies
- Pediatric Urology and Nephrology Studies
- Renal and related cancers
- Blood Pressure and Hypertension Studies
- Genetic and Kidney Cyst Diseases
- Adolescent and Pediatric Healthcare
- Cardiovascular Health and Disease Prevention
- Sodium Intake and Health
- Central Venous Catheters and Hemodialysis
- Renal function and acid-base balance
- Parathyroid Disorders and Treatments
- Birth, Development, and Health
- Urinary Tract Infections Management
- Ion Transport and Channel Regulation
- COVID-19 Clinical Research Studies
- Acute Kidney Injury Research
- Renal Transplantation Outcomes and Treatments
- Electrolyte and hormonal disorders
- Childhood Cancer Survivors' Quality of Life
- Complement system in diseases
- Renal and Vascular Pathologies
- Renal cell carcinoma treatment
- Sepsis Diagnosis and Treatment
- Biomedical Research and Pathophysiology
Vilnius University
2016-2025
Vilnius University Hospital Santariskiu Klinikos
2003-2025
Mykolas Romeris University
2023
Great Ormond Street Hospital
2017
University College London
2017
Lietuvos Bioetikos Komitetas
2015-2016
Boston Children's Hospital
2006-2014
Hôpital Edouard Herriot
1997
Université Claude Bernard Lyon 1
1997
Renal hypodysplasia (RHD) is characterized by a reduced nephron number, small kidney size, and disorganized renal tissue. A hereditary basis has been established for subset of affected patients, suggesting major role developmental genes that are involved in early organogenesis. Gene mutations have dominant inheritance cause RHD, urinary tract anomalies, defined extrarenal symptoms identified TCF2 (renal cysts diabetes syndrome), PAX2 (renal-coloboma EYA1 SIX1 (branchio-oto-renal SALL1...
We investigated the value of genetic, histopathologic, and early treatment response information in prognosing long-term renal outcome children with primary steroid-resistant nephrotic syndrome. From PodoNet Registry, we obtained longitudinal clinical for 1354 patients (disease onset at >3 months <20 years age): 612 had documented responsiveness to intensified immunosuppression (IIS), 1155 kidney biopsy results, 212 an established genetic diagnosis. assessed risk factors ESRD using...
The efficacy of continuous antibiotic prophylaxis in preventing urinary tract infection (UTI) infants with grade III, IV, or V vesicoureteral reflux is controversial. Download a PDF the Research Summary. In this investigator-initiated, randomized, open-label trial performed 39 European centers, we randomly assigned 1 to 5 months age and no previous UTIs receive (prophylaxis group) treatment (untreated for 24 months. primary outcome was occurrence first UTI during period. Secondary outcomes...
Background and objectives Autosomal dominant polycystic kidney disease is the most common inheritable disease, frequently thought to become symptomatic in adulthood. However, patients with autosomal may develop signs or symptoms during childhood, particular hypertension. Although ambulatory BP monitoring preferred method diagnose hypertension pediatrics, data children are limited. Design, setting, participants, & measurements Our retrospective multicenter study was conducted collect...
Angiotensin-converting enzyme inhibitors (ACEi) for renin-angiotensin-aldosterone system (RAAS) blockade are routinely used to slow CKD progression. However, vitamin D may also promote renoprotection by suppressing renin transcription through cross-talk between RAAS and D-fibroblast growth factor-23 (FGF-23)-Klotho pathways. To determine whether levels influence proteinuria progression in children, we performed a post hoc analysis of the Effect Strict Blood Pressure Control ACE Inhibition on...
Prevalence of isolated nocturnal hypertension (INH) and daytime (IDH) is around 10% in adults. Data children, especially chronic kidney disease (CKD), are lacking. The aim this cross-sectional multicenter cohort study was to define the prevalence INH IDH its association with cardiovascular morphology function, that is, pulse wave velocity (PWV), carotid intima-media thickness (cIMT), or left ventricular mass index (LVMI) children CKD.Ambulatory blood pressure (BP) monitoring profiles were...
The European Rare Kidney Disease Reference Network (ERKNet) recently established ERKReg, a Web-based registry for all patients with rare kidney diseases. main objectives of this core are to generate epidemiological information, identify current patient cohort clinical research, explore diagnostic and therapeutic management practices, monitor treatment performance patient's outcomes. has modular design that allows integrate comprehensive disease-specific registries as extensions the database....
Abstract Background Currently used pediatric kidney length normative values are based on small single-center studies, do not include function assessment, and focus mostly newborns infants. We aimed to develop ultrasound-based derived from a large group of European Caucasian children with normal function. Methods Out 1,782 aged 0–19 years, 1,758 individuals no present or past disease estimated glomerular filtration rate had sonographic assessment length. The results were correlated...
The overlap of coronavirus disease 2019 (COVID-19) with other common respiratory pathogens may complicate the course and prognosis. aim study was to evaluate rates, characteristics, outcomes pediatric patients severe acute syndrome 2 (SARS-CoV-2), syncytial virus (RSV), influenza A/B infections, their coinfections. A single-center prospective cross-sectional performed at emergency department in Vilnius from 1 October 2021 30 April 2022. In total, 5127 children were screened for SARS-CoV-2,...
Autosomal recessive polycystic kidney disease (ARPKD) is a rare but frequently severe disorder that typically characterized by cystic kidneys and congenital hepatic fibrosis displays pronounced phenotypic heterogeneity. ARPKD among the most important causes for pediatric end stage renal leading reason liver-, kidney- or combined liver transplantation in childhood. The underlying pathophysiology, mechanisms resulting observed clinical heterogeneity long-term evolution of patients remain...
There are three principle forms of vascular access available for the treatment children with end stage kidney disease (ESKD) by haemodialysis: tunnelled catheters placed in a central vein (central venous lines, CVLs), arteriovenous fistulas (AVF), and grafts (AVG) using prosthetic or biological material. Compared adult literature, there few studies to provide evidence based guidelines optimal type its management outcomes ESKD.The European Society Paediatric Nephrology Dialysis Working Group...
Nutritional iron deficiency (ID) causes not only anemia but also malfunction of the entire human organism. Recently, a role gut microbiota has been hypothesized, limited data are available especially in infants. Here, we performed pilot study to explore 10 patients with (IDA) and healthy controls aged 6–34 months. Fresh stool samples were collected from diapers, fecal was profiled by next-generation sequencing V3–V4 hypervariable region 16S rRNA gene. Except for diet diversity, breastfeeding...
The joint statement is a synergistic action between HyperChildNET and the European Academy of Pediatrics about diagnosis management hypertension in youth, based on Society Hypertension Guidelines published 2016 with aim to improve its implementation. first most important requirement for an accurate measurement office blood pressure that currently recommended screening, diagnosis, high children adolescents. Blood levels should be screened all starting from age 3 years. In those risk factors...