Sara Testa
- Dialysis and Renal Disease Management
- Complement system in diseases
- Renal Diseases and Glomerulopathies
- Central Venous Catheters and Hemodialysis
- Renal Transplantation Outcomes and Treatments
- Pediatric Urology and Nephrology Studies
- Chronic Kidney Disease and Diabetes
- Renal function and acid-base balance
- Escherichia coli research studies
- Metabolism and Genetic Disorders
- Neonatal Health and Biochemistry
- Acute Kidney Injury Research
- Electrolyte and hormonal disorders
- Muscle and Compartmental Disorders
- Blood groups and transfusion
- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Folate and B Vitamins Research
- Porphyrin Metabolism and Disorders
- Diet and metabolism studies
- Genetic and Kidney Cyst Diseases
- Viral gastroenteritis research and epidemiology
- Adolescent and Pediatric Healthcare
- Blood Pressure and Hypertension Studies
- Renal and related cancers
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2014-2024
Ospedale SS. Annunziata
2024
IRCCS Humanitas Research Hospital
2022
Ospedale Maggiore
2004-2021
University of Parma
2020
University of Milan
1999-2019
Istituti di Ricovero e Cura a Carattere Scientifico
2004-2018
Center for Disease Control
2015
Policlinico San Matteo Fondazione
2004
University of Genoa
1998-2000
The ItalKid Project is a prospective, population-based registry that was started in 1990 with the aim of assessing epidemiology childhood chronic renal failure (CRF), describing natural history disease, and identifying factors influence its course. This article reports epidemiologic results.Prevalent incident cases CRF children adolescents were identified throughout Italy (total population base: 16.8 million children) by regularly asking all pediatric hospitals adult nephrology units...
Background and objectives Steroid-resistant nephrotic syndrome is a rare kidney disease involving either immune-mediated or genetic alterations of podocyte structure function. The nature, heterogeneity, slow evolution the disorder are major obstacles to systematic genotype-phenotype, intervention, outcome studies, hampering development evidence-based diagnostic therapeutic concepts. To overcome these limitations, PodoNet Consortium has created an international registry for congenital...
Hemolytic uremic syndrome associated with Shiga toxin-producing Escherichia coli (STEC-HUS) is a severe acute illness without specific treatment except supportive care; fluid management concentrated on preventing overload for patients, who are often oligoanuric. Hemoconcentration at onset more disease, but the benefits of volume expansion after hemolytic (HUS) have not been explored.All children STEC-HUS referred to our center between 2012 and 2014 received intravenous infusion targeted...
To analyse the timing of end stage renal disease in children with chronic kidney (CKD).A population-based cohort study.A nationwide registry (ItalKid Project) collecting information on all patients CKD aged <20 years.935 secondary to hypodysplasia or without urologic malformation. In a subgroup (n=40) detailed pubertal staging was analysed relation progression.Kidney survival (KS) estimated using replacement therapy (RRT) as end-point. Puberty staged by identifying growth spurt.A non-linear...
Autosomal recessive polycystic kidney disease (ARPKD) is a rare but frequently severe disorder that typically characterized by cystic kidneys and congenital hepatic fibrosis displays pronounced phenotypic heterogeneity. ARPKD among the most important causes for pediatric end stage renal leading reason liver-, kidney- or combined liver transplantation in childhood. The underlying pathophysiology, mechanisms resulting observed clinical heterogeneity long-term evolution of patients remain...
No AccessJournal of UrologyPediatric Urology1 Jul 2004LONG-TERM OUTCOME OF VESICOURETERAL REFLUX ASSOCIATED CHRONIC RENAL FAILURE IN CHILDREN. DATA FROM THE ITALKID PROJECT GIANLUIGI ARDISSINO, LUIGI AVOLIO, VALERIA DACCO, SARA TESTA, GIUSEPPINA MARRA, VIGANÒ, SILVANA LOI, PAOLO CAIONE, ROBERTO DE CASTRO, SALVATORE PASCALE, EFISIA MARRAS, GIOVANNA RICCIPETITONI, GIORGIO SELVAGGIO, PAOLA PEDOTTI, ALDO CLARIS-APPIANI, ANTONIO CIOFANI, LUCA DELLO STROLOGO, GIULIANA LAMA, GIOVANNI MONTINI, and...
Increased left ventricular (LV) mass in children with chronic renal insufficiency (CRI) might be adaptive to sustain myocardial performance the presence of increased loading conditions. It was hypothesized that CRI, LV systolic function is impaired despite (LVM). Standard echocardiograms were obtained 130 predialysis who aged 3 18 yr (59% boys) and had stages II through IV kidney disease healthy similar age, gender distribution, body build. Systolic assessed by measurement fractional...
Conventional methods to diagnose and monitor chronic kidney disease (CKD) in children, such as creatinine level cystatin C-derived estimated glomerular filtration rate (eGFR) assessment of proteinuria spot or timed urine samples, are limited value identifying patients at risk progressive function loss. Serum soluble urokinase receptor (suPAR) levels strongly predict incident CKD stage 3 adults.
Encapsulating peritoneal sclerosis (EPS) is a rare complication of dialysis (PD) that associated with significant morbidity and mortality in adults. There are scarce data for children. We performed 10-year survey to determine the prevalence, risk factors outcome EPS Chronic PD patients 14 units participating European Paediatric Dialysis Working Group between January 2001 December 2010 were included this study. Twenty-two cases reported (prevalence 1.5%; 8.7 per 1000 patient-years on PD)....
Abstract While children approaching end-stage kidney disease (ESKD) are considered at risk of uremic anorexia and underweight they also exposed to the global obesity epidemic. We sought investigate variation nutritional status in undergoing chronic peritoneal dialysis (CPD) around globe. The distribution course body mass index (BMI) standard deviation score over time was examined prospectively 1001 adolescents from 35 countries starting CPD who were followed International Pediatric PD...
Background. Chronic kidney diseases (CKD) tend to progress end-stage renal failure (ESRF). As it has been demonstrated that angiotensin-converting enzyme inhibitors (ACEi) have a renoprotective effect in adults with proteinuric disease and may be effective reducing hyperfiltration proteinuria, they are also frequently used as anti-progression agents paediatric patients CKD despite the lack of data confirming their role nephropathies peculiar children. The aim this study was investigate...