Rajiv Sinha
A5057538715- Renal Diseases and Glomerulopathies
- Pediatric Urology and Nephrology Studies
- Dialysis and Renal Disease Management
- Acute Kidney Injury Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Complement system in diseases
- Urinary Bladder and Prostate Research
- Renal and related cancers
- Central Venous Catheters and Hemodialysis
- Urinary Tract Infections Management
- Ion Transport and Channel Regulation
- Neonatal Health and Biochemistry
- Pregnancy and Medication Impact
- Blood Pressure and Hypertension Studies
- Renal Transplantation Outcomes and Treatments
- Muscle and Compartmental Disorders
- Systemic Lupus Erythematosus Research
- Kidney Stones and Urolithiasis Treatments
- Renal function and acid-base balance
- Nerve Injury and Rehabilitation
- Adolescent and Pediatric Healthcare
- Genetic and Kidney Cyst Diseases
- Biomedical Research and Pathophysiology
- Poisoning and overdose treatments
- Electrolyte and hormonal disorders
Institute of Child Health
2016-2025
Nalanda Medical College and Hospital
2023-2024
Indira Gandhi Institute of Medical Sciences
2016-2023
All India Institute of Medical Sciences
2023
Apollo Gleneagles Hospitals
2019-2023
Ericsson (Sweden)
2023
AMRI Hospitals
2011-2022
Axis Multispecialty Hospital
2022
Fortis Hospital
2013-2020
Medanta The Medicity
2020
Primary distal renal tubular acidosis (dRTA) is a rare disorder, and we aimed to gather data on treatment long-term outcome. We contacted paediatric adult nephrologists through European professional organizations. Responding clinicians entered demographic, biochemical, genetic clinical in an online form. Adequate were collected 340 patients (29 countries, female 52%). Mutation testing had been performed 206 (61%); pathogenic mutations identified 170 (83%). The median (range) presentation age...
Significance Statement Children with frequently relapsing, steroid-dependent nephrotic syndrome (FRSDNS) often require multiple courses of rituximab. However, long-term effects from repeated treatments remain unknown. In this international, multicenter study 346 children receiving 1149 rituximab, the risk relapse decreased and relapse-free survival significantly improved treatments. Important side effects, including hypogammaglobulinemia, neutropenia, infections, were mostly mild, but...
The efficacy and safety of rituximab in childhood steroid-resistant nephrotic syndrome (SRNS) remains unclear. Therefore, we conducted a retrospective cohort study at 28 pediatric nephrology centers from 19 countries Asia, Europe, North America Oceania to evaluate this. Children with SRNS treated were analyzed according the duration calcineurin inhibitors (CNIs) treatment before [6 months or more (CNI-resistant) under 6 months]. Primary outcome was complete/partial remission (CR/PR) as...
Background Children are recognised as at lower risk of severe COVID-19 compared with adults, but the impact immunosuppression is yet to be determined. This study aims describe clinical course in children kidney disease taking immunosuppressive medication and assess severity. Methods Cross-sectional hosted by European Rare Kidney Disease Reference Network supported European, Asian International paediatric nephrology societies. Anonymised data were submitted online for any child (age <20...
Background: Atypical hemolytic uremic syndrome (aHUS), an important cause of acute kidney injury (AKI), is characterized by dysregulation the alternative complement pathway. Autoantibodies to factor H (FH), a chief regulator this pathway, account for distinct subgroup. While high anti-FH titers predict relapse, they do not correlate well with disease activity and their functional characterization required. Methods: Of 781 patients <18-year-old aHUS in nationwide database from 2007 2018, 436...
Cervical facet dislocations may be reduced rapidly and effectively using axial traction with weights applied at over the traditional 45-pound limit. Fifty-three sequential patients cervical were reviewed. Thirty-nine required more than 50 pounds of to achieve rapid reduction. Sixty-eight percent entire series showed significant improvement in neurologic function. There no cases loss A cadaver study confirmed that cranial tongs could support 100 traction. Careful application up seems...
Little published information is available about access failure in children undergoing chronic peritoneal dialysis. Our objectives were to evaluate frequency, risk factors, interventions, and outcome of dialysis revision.Data derived from 824 incident 1629 prevalent patients 105 pediatric nephrology centers enrolled the International Pediatric Peritoneal Dialysis Network Registry between 2007 2015.In total, 452 revisions recorded 321 (13%) 2453 over 3134 patient-years follow-up, resulting an...
Abstract While children approaching end-stage kidney disease (ESKD) are considered at risk of uremic anorexia and underweight they also exposed to the global obesity epidemic. We sought investigate variation nutritional status in undergoing chronic peritoneal dialysis (CPD) around globe. The distribution course body mass index (BMI) standard deviation score over time was examined prospectively 1001 adolescents from 35 countries starting CPD who were followed International Pediatric PD...
ABSTRACT Background Immunoglobulin A vasculitis with nephritis (IgAVN) is the most common in children. Due to a lack of evidence, treatment recommendations are based on expert opinion, resulting variation. The aim this study was describe clinical presentation, and outcome an extremely large cohort children biopsy-proven IgAVN order identify prognostic risk factors signals efficacy. Methods Retrospective data were collected 1148 between 2005 2019 from 41 international paediatric nephrology...
The acute-stage mortality and morbidity of acute renal failure (ARF) is well documented, but there are few long-term follow-up studies in children with ARF, particularly from developing countries. aim this study was to look at the spectrum ARF on presentation a tertiary centre Kolkata, India, subsequent 10 years follow-up.All cases between ages 1 month presenting April September 1996 were included. We did exclude any known abnormality. group subsequently monitored for survival until post-ARF...