A5050735058- Bone and Dental Protein Studies
- Periodontal Regeneration and Treatments
- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Alkaline Phosphatase Research Studies
- dental development and anomalies
- Biochemical and Molecular Research
- Proteoglycans and glycosaminoglycans research
- Oral microbiology and periodontitis research
- Endodontics and Root Canal Treatments
- Bone health and treatments
- Polyamine Metabolism and Applications
- Ion channel regulation and function
- Cleft Lip and Palate Research
- Glycosylation and Glycoproteins Research
- Cell Adhesion Molecules Research
- Dental Erosion and Treatment
- Amino Acid Enzymes and Metabolism
- Enzyme function and inhibition
- Connexins and lens biology
- Craniofacial Disorders and Treatments
- Bone fractures and treatments
- Oral and Maxillofacial Pathology
- Hedgehog Signaling Pathway Studies
- Dental Radiography and Imaging
University of Gothenburg
2005-2022
Göteborgs Stads
1997-2015
Rostov Research Institute of Oncology
2013
Shell (Netherlands)
2012
Lund University
1997-1999
University of North Carolina at Chapel Hill
1988-1989
University of Bern
1989
University of Alabama at Birmingham
1980-1983
Chalmers University of Technology
1983
Swedish Research Council
1980
In this study we describe a principle for the accomplishment of bone regeneration based on hypothesis that different cellular components in tissue have varying rates migration into wound area during healing. By mechanical hindrance, using membrane technique, fibroblasts and other soft connective-tissue cells are prevented from entering defect so presumably slower-migrating with osteogenic potential allowed to repopulate defect. Defects standard size were created bilaterally through...
Sonic hedgehog (Shh), a member of the mammalian Hedgehog(Hh) family, plays key role during embryogenesis and organogenesis. Tooth development, odontogenesis, is governed by sequential reciprocal epithelial-mesenchymal interactions. Genetic removal Shh activity from dental epithelium, sole source tooth alters growth cytological organization within both epithelium mesenchyme tooth. In this model it not clear which aspects phenotype are result direct action on target tissue indirect effects due...
AbstractCyst-like cavities in the jaw bone often heal incompletely owing to ingrowth of connective tissue, thus preventing osteogenesis from occurring. In present study, a new membrane technique has been utilized an attempt improve healing. By means inert, porous membrane, placed close contact with surface, secluded space is created which can only be repopulated by cells adjacent bone.Thus, able occur without interference other tissue types. Through-and-through defects were produced...
Lack of bone in localized areas the jaws frequently poses a problem when placing oral implants. In this clinical study, we have tested an osteopromotive membrane technique for its ability to create over buccal fenestrations after fixture installation maxilla. 7 patients were selected by use CT‐scan. Criteria patient selection that alveolar crest should vertical height >I3 mm and facial‐palatal concavity, where exposure at central portion could be anticipated. One fenestration, randomly...
Noncollagenous proteins (NCPs) were obtained from rat dentin using several precautionary measures to prevent artifactual degradation and losses of the proteins.Prior demineralization, incisor was extracted with 4 M guanidine hydrochloride (GdmCl) containing enzyme inhibitors.The only major component GdmCl a proteoglycan fraction.Most NCPs when incisors decalcified an EDTA solution protease extract contained four types macromolecules: acidic glycoproteins, y-carboxyglutamic acid...
Abstract Modifying the chemistry of injection water yields improved wettability behavior on carbonate rock surfaces. Previous work has focused demonstrating effect modified brine formulation particular samples. Here results a more general screening study consisting Amott spontaneous imbibition experiments samples from oil-bearing zones and outcrops different formations are reported. Tertiary incremental oil production due to increased water-wetness was observed upon transition lower ionic...
✓ Various techniques for treatment of large cranial defects have been reported, but the use alloplastic materials still seems to predominate. The authors applied and explored a new approach bone repair which appears promising, even in less osteogenic environments such as adult calvaria. Seventy-two Sprague-Dawley rats each received bilateral 8-mm trephine temporoparietal area; this defect size precludes spontaneous osseous healing during lifetime animal. Five surgical procedures, employing...
T he research reviewed in this paper constitutes a series of investigations intended to develop and evaluate new membrane technique, which provides improved conditions for osteogenesis during healing bone defects restitution earlier existing bone. The technique has also been shown aid grafting as well having the capacity create reconstructive purposes. According methodology, membranes are utilized space tissue can occur relatively unimpeded. review our initial animal experimental work some...
The dental pulp is a loose connective tissue, characterized by its specific anatomical location. Its extracellular components are obvious subjects for study, since such largely responsible the physiological properties of tissue. Several clinically important processes occur ex-tracellularly, e.g., defense mechanisms as inflammatory reactions and formation calcified mesenchyme has crucial role during early tooth morphogenesis. pulp, or rather papilla, seems to have only an indirect...
This study was undertaken to investigate whether the choice of carrier/delivery system might be crucial for rhBMP-2 induced osteogenesis beneath osteopromotive membranes. Standardized 5-mm transosseous rat mandibular defects were implanted with recombinant human BMP-2 (rhBMP-2) or without membrane placement. Two doses (1 μg and 8 per defect) delivered either collagen sponge bioabsorbable poly(D,L-lactide-co-glycolide) (PLA/PGA) beads plus allogenic blood as carriers. Membrane-covered (no...
Ninety-nine individuals, all of whom had long avoided dental treatment due to severe fear, received therapy according one two modalities - behavioral from a psychologist (BT) and under general anesthesia (GA) both which were followed by clinical training test treatments. These programs referring the individuals community clinics for complete oral rehabilitation. Among BT patients, significantly more (92%) completed program, compared with GA patients (69%). Complete rehabilitation in was...