A5063023583- Stochastic processes and statistical mechanics
- Schizophrenia research and treatment
- Theoretical and Computational Physics
- Mental Health and Psychiatry
- Psychosomatic Disorders and Their Treatments
- Advanced Thermodynamics and Statistical Mechanics
- Mathematical and Theoretical Epidemiology and Ecology Models
- Evolution and Genetic Dynamics
- Stochastic processes and financial applications
- Bipolar Disorder and Treatment
- Neural and Behavioral Psychology Studies
- Action Observation and Synchronization
- Neurobiology of Language and Bilingualism
- Evolutionary Game Theory and Cooperation
- Quantum many-body systems
- Empathy and Medical Education
- Cold Atom Physics and Bose-Einstein Condensates
- Random Matrices and Applications
- Nonlinear Dynamics and Pattern Formation
- Electroconvulsive Therapy Studies
- Mental Health Research Topics
- Psychoanalysis and Psychopathology Research
- Functional Brain Connectivity Studies
- Diffusion and Search Dynamics
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Hôpital André Mignot
2000-2024
Centre Hospitalier de Versailles
2015-2024
Fondation FondaMental
2010-2024
Université de Versailles Saint-Quentin-en-Yvelines
2015-2024
Centre de recherche en Epidémiologie et Santé des Populations
2020-2024
Inserm
2006-2024
Université Paris-Saclay
2015-2024
Hôpital Albert-Chenevier
2020-2024
École Normale Supérieure - PSL
2003-2023
Université Paris Sciences et Lettres
2017-2023
We consider the effect of a small cutoff $\ensuremath{\varepsilon}$ on velocity traveling wave in one dimension. Simulations done over more than ten orders magnitude as well simple theoretical argument indicate that is to select single converges when $\ensuremath{\varepsilon}\ensuremath{\rightarrow}0$ predicted by marginal stability argument. For $\ensuremath{\varepsilon}$, shift has form $K(\mathrm{ln}\ensuremath{\varepsilon}{)}^{\ensuremath{-}2}$ and our prediction for constant $K$ agrees...
We consider a family of models describing the evolution under selection population whose dynamics can be related to propagation noisy traveling waves. For one particular model that we shall call exponential model, properties wave front calculated exactly, as well statistics genealogy population. One striking result is that, for this genealogical trees have same replicas in Parisi mean-field theory spin glasses. also find coalescence times along these grow like logarithm size. A...
We propose a phenomenological description for the effect of weak noise on position front described by Fisher-Kolmogorov-Petrovsky-Piscounov equation or any other traveling-wave in same class. Our scenario is based four hypotheses relevant mechanism diffusion front. parameter-free analytical predictions velocity front, its constant and higher cumulants agree with numerical simulations.
We study the limiting distribution of particles at frontier a branching random walk. The positions these can be viewed as lowest energies directed polymer in medium mean-field case. show that average distances between leading computed delay traveling wave evolving according to Fisher-KPP front equation. These exhibit universal behaviors, different from those probability cascades studied recently context spin-glasses.
Several studies have shown that schizophrenic patients impaired theory-of-mind skills involving the attribution of false beliefs and intentions to others. Despite methodological difficulties belief protocols, experiments concluded deficit is specific cannot be explained in terms a general cognitive impairment. The situation, however, remains unclear as far others concerned. We propose use nonverbal control tasks based on physical causality demonstrate specificity impairment intentions.We...
For a family of models evolving population under selection, which can be described by noisy traveling-wave equations, the coalescence times along genealogical tree scale like ln αN, where N is size population, in contrast with neutral for they N. An argument relating this time to diffusion constant traveling wave leads prediction α agrees our simulations. exactly soluble case gives trees statistics identical those predicted mean-field spin glasses Parisi's theory.
Abstract In a recent article, Desai and Fisher proposed that the speed of adaptation in an asexual population is determined by dynamics stochastic edge population, is, emergence subsequent establishment rare mutants exceed fitness all sequences currently present population. perform elaborate calculation mean time τ until new class has been established interpret 1/τ as adaptation. As they note, however, their calculations are valid only for moderate speeds. This limitation arises from method...
We calculate exactly the first cumulants of free energy a directed polymer in random medium for geometry cylinder. By using fact that nth moment <Z(n)> partition function is given by ground-state quantum problem n interacting particles on ring length L, we write an integral equation allowing to expand these moments powers strength disorder gamma or n. For small and approximately (Lgamma)(-1/2), take scaling form which allows us describe all fluctuations order 1/L per unit polymer. The...
Longitudinal studies of the relationship between cognition and functioning in bipolar disorder are scarce, although is thought to be a key determinant functioning. The causal structure psychosocial unknown.We sought examine direction causality cognitive performance functional outcome over 2 years large cohort euthymic patients with disorder.The sample consisted 272 adults diagnosed who were at baseline, 12 24 months. All participants recruited via FondaMental Advanced Centers Expertise...
Background: Numerous studies have demonstrated the existence of theory mind (ToM) impairments in patients with schizophrenia. The clinical consequences these are currently under debate. Accumulated evidence suggests that ToM deficits linked to negative and disorganization symptoms, but direct correlations lacking. Moreover, it is unclear whether related reduced quality life (QoL). Methods: To extend understanding objective (i.e., symptoms) subjective (QoL) correlates impaired ToM, we...