A5101432301- Stochastic processes and statistical mechanics
- Stochastic processes and financial applications
- Theoretical and Computational Physics
- Markov Chains and Monte Carlo Methods
- Financial Risk and Volatility Modeling
- Probability and Risk Models
- Diffusion and Search Dynamics
- Mathematical Dynamics and Fractals
- Data Mining Algorithms and Applications
- advanced mathematical theories
- Random Matrices and Applications
- Bayesian Methods and Mixture Models
- Data Management and Algorithms
- Chemokine receptors and signaling
- Cancer-related molecular mechanisms research
- Complex Network Analysis Techniques
- Complex Systems and Time Series Analysis
- Evolution and Genetic Dynamics
- Algebraic structures and combinatorial models
- Evolutionary Game Theory and Cooperation
- Hepatocellular Carcinoma Treatment and Prognosis
- Insurance, Mortality, Demography, Risk Management
- Point processes and geometric inequalities
- Pancreatic and Hepatic Oncology Research
- Sinusitis and nasal conditions
Nantong University
2021-2024
Nanjing Drum Tower Hospital
2021-2024
Affiliated Hospital of Nantong University
2021-2024
Yancheng Third People's Hospital
2018-2024
Chinese Academy of Sciences
2024
ShanghaiTech University
2023
Laboratoire de Probabilités, Statistique et Modélisation
2016-2023
Beijing Institute of Technology
2023
Academy of Mathematics and Systems Science
2023
Sorbonne Université
2006-2021
This paper approaches the problem of computing price an Asian option in two different ways. Firstly, exploiting a scaling property, we reduce to solving parabolic PDE variables. Secondly, provide lower bound which is so accurate that it essentially true price.
Myocardin is a cardiac- and smooth muscle-specific transcription co-factor that potently activates the expression of downstream target genes. Previously, we demonstrated overexpression myocardin inhibited proliferation muscle cells (SMCs). Recently, was reported to induce microRNA-1 (miR-1) in cardiomyocytes. In this study, investigated whether induces miR-1 mediate its inhibitory effects on SMC proliferation.Using tetracycline-regulated (T-REx) inducible system expressing human vascular...
We consider the boundary case (in sense of Biggins and Kyprianou [Electron. J. Probab. 10 (2005) 609–631] in a one-dimensional super-critical branching random walk, study additive martingale $(W_{n})$. prove that, upon system's survival, $n^{1/2}W_{n}$ converges probability, but not almost surely, to positive limit. The limit is identified as constant multiple sure limit, discovered by [Adv. Appl. 36 (2004) 544–581], derivative martingale.
Abstract Drug resistance and tumor recurrence are major challenges in cancer treatment. Cancer cells often display centrosome amplification. To maintain survival, achieve bipolar division by clustering supernumerary centrosomes. Targeting is therefore considered a promising therapeutic strategy. However, the regulatory mechanisms of remain unclear. Here we report that KIFC1, regulator, positively associated with recurrence. Under DNA damaging treatments, ATM ATR kinases phosphorylate KIFC1...
Let $X$ be a strongly symmetric recurrent Markov process with state space $S$ and let $L_t^x$ denote the local time of at $X \in S$. For fixed element 0 in S, $$ \tau(t) := \inf \{s: L^0_s > t \}. The 0-potential density, $u_{\{0\}}(x, y)$, killed $T_0 = \{s:X_s =0\}$ is positive definite. $\eta \{\eta_x; x S \}$ mean-zero Gaussian covariance E_\eta (\eta_x \eta_y ) u_{\{0\}}(x, y). main result this paper following generalization classical second Ray–Knight theorem: for any $b R$ $t 0$,...
Pancreatic cancer is among the most lethal malignant neoplasms, and few patients with pancreatic benefit from immunotherapy. We retrospectively analyzed advanced who received PD-1 inhibitor-based combination therapies during 2019-2021 in our institution. The clinical characteristics peripheral blood inflammatory markers (neutrophil-to-lymphocyte ratio [NLR], platelet-to-lymphocyte [PLR], lymphocyte-to-monocyte [LMR], lactate dehydrogenase [LDH]) were collected at baseline. Chi-squared...
The high-mobility group protein A2 (HMGA2) is an architectural transcription factor that plays a crucial role in the development and progression of various malignant cancers. However, function HMGA2 bladder cancer remains largely unknown. Therefore, we aim to investigate effect on proliferation, migration, invasion, epithelial-mesenchymal transition (EMT) cells. expression human cells was downregulated by small interfering RNA (siRNA). levels other related proteins were detected Western...
Abstract Chemicals or drugs can accumulate within biomolecular condensates formed through phase separation in cells. Here, we use super-resolution imaging to search for chemicals that induce transition chromatin at the microscale. This microscopic screening approach reveals adriamycin (doxorubicin) — a widely used anticancer drug is known interact with specifically induces visible local condensation and global conformational change of cancer primary Hi-C ATAC-seq experiments systematically...
We study the sample path asymptotics of a class recurrent diffusion processes with random potentials, including examples Sinai’s simple walk in environment and Brox’s process Brownian potential. The main results consist several integral criteria which completely characterize all possible Lévy classes, therefore providing very precise image almost sure asymptotic behaviors these processes.
The main goal of this paper is to present an explicit capacity estimate for hitting probabilities the Brownian sheet. As applications, we determine escape rates sheet and also obtain a local intersection equivalence between additive motion. Other applications concern quasisure properties in Wiener space.
This paper approaches the problem of computing price an Asian option in two different ways. Firstly, exploiting a scaling property, we reduce to solving parabolic PDE variables. Secondly, provide lower bound which is so accurate that it essentially true price.
Considérons une marche aléatoire branchante surcritique à temps discret. Nous nous intéressons la probabilité qu'il existe un rayon infini du support de branchante, le long duquel elle croît plus vite qu'une fonction linéaire pente γ − ε, où désigne vitesse asymptotique position particule droite dans branchante. Sous des hypothèses générales peu restrictives, prouvons que, lorsque ε → 0, cette décroît comme exp{−(β+o(1)) / ε1/2}, β est constante strictement positive dont valeur dépend loi...
Motivated by an evolutionary biology question, we study the following problem: consider hypercube $\{0,1\}^L$ where each node carries independent random variable uniformly distributed on $[0,1]$, except $(1,1,\ldots,1)$ which value $1$ and $(0,0,\ldots,0)$ $x\in[0,1]$. We number $\Theta$ of paths from vertex to opposite along values nodes form increasing sequence. show that if is set $x=X/L$ then $\Theta/L$ converges in law as $L\to\infty$ $\mathrm{e}^{-X}$ times product two standard...
We consider the slow movement of randomly biased random walk $(X_n)$ on a supercritical Galton-Watson tree, and are interested in sites tree that most visited by walk. Our main result implies tightness distributions under annealed measure. This is contrast with one-dimensional case, provides, to best our knowledge, first non-trivial example null recurrent whose not transient, question originally raised Erdős Révész for simple symmetric line.