A5101560726- Toxic Organic Pollutants Impact
- Atmospheric chemistry and aerosols
- Air Quality and Health Impacts
- Environmental Toxicology and Ecotoxicology
- Protein Structure and Dynamics
- Metaheuristic Optimization Algorithms Research
- Biochemical and Structural Characterization
- RNA modifications and cancer
- Monoclonal and Polyclonal Antibodies Research
- Tea Polyphenols and Effects
- Air Quality Monitoring and Forecasting
- Vehicle Routing Optimization Methods
- Natural Antidiabetic Agents Studies
- Neuropeptides and Animal Physiology
- Glycosylation and Glycoproteins Research
- Gut microbiota and health
- Epigenetics and DNA Methylation
- Fish Ecology and Management Studies
- Receptor Mechanisms and Signaling
- Cancer-related molecular mechanisms research
- Health, Environment, Cognitive Aging
- Ginseng Biological Effects and Applications
- Arsenic contamination and mitigation
- Radioactivity and Radon Measurements
- Connective Tissue Growth Factor Research
Shanghai Institute of Materia Medica
2025
Chinese Academy of Sciences
2025
University of Chinese Academy of Sciences
2025
Shanghai Electric (China)
2024
Anhui University of Technology
2023
Guangzhou Women and Children Medical Center
2022
Sixth Affiliated Hospital of Sun Yat-sen University
2022
Sun Yat-sen University
2022
Guangzhou Medical University
2022
Shenyang Pharmaceutical University
2020-2021
The water-soluble organic fractions of aerosol samples collected in Riverside, CA, summer 2005 were analyzed by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS). Elemental compositions about 1000 molecular species determined the range m/z 220-420, and four series compounds identified, fulvic acids, S-containing, N-containing, S- N-containing molecules. Low-resolution product spectra proved presence organosulfates, organonitrates, mixed...
In the United States, residential wood combustion (RWC) is responsible for 7.0% of national primary PM2.5 emissions. Exposure to RWC smoke represents a potential human health hazard. Organic components particles absorb light at 370 nm more effectively than 880 in two-wavelength aethalometer measurements. This enhanced absorption (Delta-C = BC370 – BC880 nm) can serve as an indicator particles. this study, Delta-C data along with measurements molecular markers and potassium were used identify...
Lake trout and walleye composites were collected between 2004 2009 as part of the Great Lakes Fish Monitoring Surveillance Program (GLFMSP) analyzed for polybrominated diphenyl ethers (PBDEs). Yearly mean total PBDE concentrations (sum congeners BDE-47, BDE-99, BDE-100, BDE-153, BDE-154) ranged from 44-192, 28-113, 50-107, 37-111, 11-22 ng/g wet wt. Michigan, Huron, Ontario, Superior lake trout, Erie walleye, respectively. A 1980-2009 temporal record in Lakes' top predator fish (lake...
Ginseng, as a functional food, is widely used worldwide because of its multifarious benefits. Studies have verified that 25-hydroxyl-protopanaxatriol (T19) new ginsenoside from ginseng, which had an important inhibitory effect on α-glucosidase and protein tyrosine phosphatase 1B in vitro. This study aims to assess the regulation T19 against glycolipid metabolism by insulin-resistant HepG2 cells diabetes mice induced with high-fat diet combined streptozotocin (STZ). effectively lowered levels...
Objective: GuHong is an intravenous herbal formulation used as adjunct therapy for the management of ischemic stroke. This investigation aimed to evaluate its potential precipitate pharmacokinetic drug interactions. To facilitate assessment, a human multi-compound study, along with associated supportive studies, was conducted pinpoint compounds testing. Methods: After analyzing chemical composition GuHong, study in healthy subjects who received intravenously identify significantly exposed...
PM2.5 samples were collected from June to December 2005 in Potsdam, New York and analyzed for polar organic compounds by GC/MS. The major that identified the included 2-methyltetrols (2-methylthreitol 2-methylerythritol), levoglucosan, cispinonic acid, mannitol. 2-Methyltetrols quantified during analysis. A seasonal variation these two diastereoisomers was observed, with highest concentrations occurring summer lowest winter. OC/EC analyses of also performed. carbon contribution OC found...
Objective: A pilot study was conducted to test the feasibility of using Department Defense Serum Repository (DoDSR) samples health and exposure-related effects. Methods: Thirty unidentified human serum were obtained from DoDSR analyzed for normal metabolites with high-resolution mass spectrometry levels free benzo(a)pyrene (BaP) by gas chromatography-mass spectrometry. Metabolic associations BaP determined a metabolome-wide association (MWAS) metabolic pathway enrichment. Results: The...
The objectives were: 1) measure polycyclic aromatic hydrocarbons (PAHs), polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) in 100 μL of human serum 2) assess PAH PCDD/PCDF as markers burn pit exposures during military deployments.PAHs PCDDs/PCDFs were analyzed samples collected pre- post-deployment from 200 persons deployed to Iraq or Afghanistan (CASE); not (CONTROL) with gas chromatography/mass spectrometry.Naphthalene was found ∼83% the statistically different between...
High endothelial venules (HEVs) are special blood vessels in the paracortical region of lymph nodes (LNs) and govern lymphocyte recruitment. LN metastasis has similarity to circulating lymphocytes homing LNs, but role HEVs progression oral pharyngeal squamous cell carcinoma (OPSCC) is unclear. In this study, we found that experienced a series morphological functional changes during OPSCC were correlated with metastasis. 9 cases 73 metastatic tumor emboli located adjacent or just out not...
Objective: To determine if service members deployed to locations with open air burn pits have different serum microRNA (miRNA) profiles after deployment compared length-of-service matched, non-deployed individuals. We also tested for correlations between miRNA and levels of Polychlorinated Dibenzo-p-Dioxins/Dibenzofurans (PCDD/PCDFs). Methods: MiRNAs were isolated quantified by PCR array. Groups analyzed differences in expression. Correlations PCDD/PCDFs assessed a linear regression model....
The aim of this study was to investigate whether serum samples from the Department Defense Serum Repository (DoDSR) are sufficient quality detect microRNAs (miRNAs), cytokines, immunoglobulin E (IgE), and polycyclic aromatic hydrocarbons (PAHs).MiRNAs were isolated quantified by polymerase chain reaction (PCR) array. Cytokines chemokines related inflammation measured using multiplex immunoassays. Cotinine IgE detected enzyme-linked immunoassay (ELISA) PAHs Liquid Chromatography/Mass...
Abstract BACKGROUND White tea, considered to be the oldest form of is becoming a popular beverage for its organoleptic characteristics. Peppermint used as herbal remedy centuries, now also very throughout world tea. What interested us was that in ancient China, peppermint combination with tea detoxification or anti‐inflammatory agent. However, there are few reports on combined use white and peppermint. Therefore, this study aims investigate antibacterial activities RESULTS A synergistic...
Instruments such as Beta Attenuation Monitors (BAMs) provide real-time PM2.5 mass concentration data and are now widely used in compliance monitoring networks. These devices collect the PM on a filter tape 1-hour samples. In this work, use of BAM spots for chemical speciation was investigated. Filter tapes from several sites California were analyzed series species including elements, ions, organic elemental carbon, molecular markers. A major issue blank values tape. Based spot analyses, it...
Prediction of the spatial structure or function biological macromolecules based on their sequences remains an important challenge in bioinformatics. When modeling using traditional sequencing models, long-range interaction, complicated and variable output labeled structures, length usually lead to different solutions a case-by-case basis. This study proposed unified deep learning architecture long short-term memory gated recurrent unit capture interactions. The designs optional reshape...