A5008598891- Tuberculosis Research and Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- Infectious Diseases and Tuberculosis
- Global Health Workforce Issues
- Pharmaceutical and Antibiotic Environmental Impacts
- Cultural Competency in Health Care
- Antibiotic Use and Resistance
- Indigenous Studies and Ecology
- Genetic diversity and population structure
- Diagnosis and treatment of tuberculosis
- Bioeconomy and Sustainability Development
- Bacterial Identification and Susceptibility Testing
- Genomics and Phylogenetic Studies
- Food Security and Health in Diverse Populations
- Mycobacterium research and diagnosis
- Pharmaceutical Quality and Counterfeiting
- Fish Biology and Ecology Studies
- Pneumonia and Respiratory Infections
- Genetic and phenotypic traits in livestock
- Indigenous Health, Education, and Rights
- Dietetics, Nutrition, and Education
- Genetics, Bioinformatics, and Biomedical Research
- Zoonotic diseases and public health
- Wildlife Ecology and Conservation
Inuit Tapiriit Kanatami
2022-2023
Ottawa Hospital Research Institute
2019-2021
Ottawa Hospital
2019-2021
University of Pretoria
2019-2020
University of KwaZulu-Natal
2013
In African countries, antimicrobial resistance (AMR) issue remains pertinent. Despite this, little efforts have been made to assess the future veterinary prescribers on their knowledge, attitudes and practices (KAP) related usage. This multi-country survey attempts explore KAP of veterinarians stewardship identify knowledge gaps. Eight schools participated from Nigeria, Sudan South Africa. Data regarding perceptions were analysed using Chi-square χ² test, Spearman's (Rho) Rank order...
Understanding the knowledge and perceptions of veterinary students antimicrobial resistance (AMR) as potential future prescribers antimicrobials may serve an opportunity to improve stewardship AMR. Pre-final (n = 42) final 29) year University Pretoria completed questionnaires determine their Of 71 respondents, mixed practice (48%) small animal (45%) were most preferred career choices post-graduation, with field gross pathology being least preferred. Over 80% respondents believed that...
Background Tuberculosis (TB) remains a significant health burden among Inuit in Canada. Social determinants of (SDH) play key role TB infection, disease and ongoing transmission this population. The objective research was to estimate the prevalence social as they relate latent infection (LTBI) people living residential areas at high risk for Iqaluit, Nunavut. Methods Inperson home surveys were conducted those who lived predetermined identified door-to-door prevention campaign Nunavut 2011....
Abstract Background A remote arctic region of Canada predominantly populated by Inuit with the country’s highest incidence tuberculosis. Methods The study was undertaken to describe latent tuberculosis infection (LTBI) cascade care and identify factors associated non-initiation non-completion LTBI treatment. Data were extracted retrospectively from medical records for all patients a tuberculin skin test (TST) implanted in Iqaluit, Nunavut between January 2012 March 2016. Associations...
Abstract Background In the last decade, tuberculosis (TB) incidence among Inuit in Canadian Arctic has been rising. Our aim was to better understand transmission dynamics of TB this remote region Canada using whole-genome sequencing. Methods Isolates from patients who had culture-positive pulmonary Iqaluit, Nunavut, between 2009 and 2015 underwent sequencing (WGS). The number events cases within clusters calculated a threshold ≤3 single nucleotide polymorphism (SNP) difference isolates then...
ABSTRACT Starch gel electrophoresis was used to analyse genetic variation at 24 enzyme and protein loci in 12 South African populations of vlei rats Otomys irroratus. Mean heterozygosity ([Hbar]: 0.071) relatively high for a mammal. Allelic within conformed Hardy-Weinberg expectations, the mean value Wright's F IS statistic (0.048) indicated no evidence inbreeding populations. There significant local differentiation allelic frequencies (Wright's ST = 0.375). However, distances between were...
Background: The incidence of TB among Inuit is the highest in Canada. A significantly shorter latent infection (LTBI) treatment with rifapentine and isoniazid once weekly for 12 weeks (3HP) now available limited settings Canada.Methods: prospective open-label 2-year observational postmarketing study was conducted introducing 3HP first time Canada Iqaluit followed by a program rollout Qikiqtarjuaq, Nunavut.Results: total 247 people were offered 3HP, 102 145 Qikiqtarjuaq roll out. Although...
We aimed to determine if offering a 12-dose once-weekly treatment (3HP) as an additional option would result in increase the overall proportion of patients completing TB preventive (TPT) above baseline rate.We analyzed outcomes consecutive adults referred clinic from January 2010 May 2019. Starting December 2016, 3HP was offered alternative standard regimens which included 9 months daily isoniazid or 4 rifampin. The primary outcome who completed TPT among all started treatment. Using...
Prevention of TB is paramount to achieving elimination targets as recommended by the World Health Organization's action framework for low incidence countries striving eliminate TB. Although rates in Canada are low, understanding latent infection (LTBI) cascade identifying gaps care and treatment barriers, thereby increasing effectiveness preventive strategies. The purpose this study was examine LTBI identify barriers completion adults referred from primary a regional tertiary clinic Ottawa,...