A5088637068- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Mycobacterium research and diagnosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Respiratory and Cough-Related Research
- Diagnosis and treatment of tuberculosis
- Pneumonia and Respiratory Infections
- Hematological disorders and diagnostics
- Blood transfusion and management
- Indigenous Studies and Ecology
- Emergency and Acute Care Studies
- Pediatric health and respiratory diseases
- Health Policy Implementation Science
- Chronic Disease Management Strategies
- Respiratory Support and Mechanisms
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- RNA modifications and cancer
- Colorectal Cancer Screening and Detection
- Child Nutrition and Water Access
- Respiratory viral infections research
- Food Security and Health in Diverse Populations
- Forensic Toxicology and Drug Analysis
- Dental Erosion and Treatment
Ottawa Hospital
2015-2024
University of Ottawa
2015-2024
St. Michael's Hospital
2024
University of British Columbia
2004-2024
McGill University
2024
University of Calgary
2024
University of Toronto
2024
University of Saskatchewan
2024
Université Laval
2024
University of Alberta
2024
Although asthma is a chronic disease, the expected rate of spontaneous remissions adult and stability diagnosis are unknown.To determine whether current could be ruled out medications safely stopped in randomly selected adults with physician-diagnosed asthma.A prospective, multicenter cohort study was conducted 10 Canadian cities from January 2012 to February 2016. Random digit dialing used recruit participants who reported history established within past 5 years. Participants using...
It is unclear whether asthma overdiagnosed in developed countries, particularly among obese individuals, who may be more likely than nonobese people to experience dyspnea.We conducted a longitudinal study involving (body mass index 20-25) and >/= 30) individuals with that had been diagnosed by physician. Participants were recruited from 8 Canadian cities means of random-digit dialing. A diagnosis current was excluded those did not have evidence acute worsening symptoms, reversible airflow...
Many persons with chronic obstructive pulmonary disease (COPD) or asthma have not received a diagnosis, so their respiratory symptoms remain largely untreated.
Background Tuberculosis is the leading cause of death in South Africa by notification, but accurate diagnosis tuberculosis challenging this setting high HIV prevalence. We conducted limited autopsies on young adults dying a single public hospital province KwaZulu-Natal between October 2008 and August 2009 order to estimate magnitude deaths attributable tuberculosis. Methods Findings studied representative sample 240 adult inpatients (aged 20–45 years) after admission Edendale Hospital....
Background. Xpert MTB/RIF, the first automated molecular test for tuberculosis, is transforming diagnostic landscape in low-income countries. However, little information available on its performance low-incidence, high-resource
Tuberculosis (TB) in migrants is an ongoing challenge several low TB incidence countries since a large proportion of these occurs from high countries. To meet challenges, utilize screening programs. The programs attempt to identify and treat those with active and/or infectious stages the disease. In addition, used manage latent or inactive disease after arrival. Between nations, considerable variation exists methods migration-associated screening. present study aimed compare immigration...
Rationale: A significant proportion of individuals with chronic obstructive pulmonary disease (COPD) and asthma remain undiagnosed. Objectives: The objective this study was to evaluate symptoms, quality life, healthcare use, work productivity in subjects undiagnosed COPD or compared those previously diagnosed, as well healthy control subjects. Methods: This multicenter population-based case-finding randomly recruited adults respiratory symptoms who had no previous history diagnosed lung from...
Tuberculosis (TB) is an infectious disease closely intertwined with stigma, discrimination, and the social determinants of health. Communities people affected by TB are experts in their care pathways, but field continues to fall short meaningfully engaging communities research. This a missed opportunity improve quality, relevance, person-centeredness, positive impact, sustainability research outputs. We acknowledge important progress that has been made date regarding community engagement TB,...
Objective-We sought to determine the accuracy and role of rapid C-reactive protein (CRP) testing in HIV-infected tuberculosis suspects.Design-We enrolled adults (≥18 years) with a cough for ≥2 weeks negative sputum smears acid-fast bacilli (AFB) KwaZulu-Natal, South Africa.Participants were evaluated pulmonary by nurse CRP, independently physician chest radiograph.Rapid CRP test results compared laboratory sent confirmation tuberculosis.Results-Among 93 participants, 55 (59%) female, mean...
In patients with a history suggestive of asthma, diagnosis is usually confirmed by spirometry bronchodilator response (BDR) or confirmatory methacholine challenge testing (MCT).We examined the proportion participants negative BDR who had positive MCT (and its predictors) result and characteristics MCT, including effects controller medication tapering temporal variability predictors change), concordance between pulmonologist asthma diagnosis.Adults self-reported physician-diagnosed were...
Abstract Background Seasonal respiratory viral infections are associated with exacerbations and morbidity among patients COPD. The real‐world clinical outcomes seasonal less well established hospitalized patients. Research Question To estimate the association between infections, 30‐day mortality, intensive care unit (ICU) admission COPD Study Design Methods We conducted an analysis of a national prospective multicenter cohort acute illness during winter seasons (2011–2015) in Canada....
Tuberculosis continues to disproportionately affect many Indigenous populations in the USA, Canada, and Greenland. We aimed investigate whether population-based tuberculosis-specific interventions or changes general health socioeconomic indicators, a combination of these factors, were associated with tuberculosis incidence populations.
Background Many people with asthma and COPD remain undiagnosed. We developed validated a new case-finding questionnaire to identify symptomatic adults undiagnosed obstructive lung disease. Methods Adults in the community no prior history of physician-diagnosed disease who self-reported respiratory symptoms were contacted via random-digit dialling. Pre- post-bronchodilator spirometry was used confirm or COPD. Predictive questions selected using multinomial logistic regression backward...
Background The incidence rate of active tuberculosis (TB) disease in the Canadian Territory Nunavut has shown a rising trend over past 10 years. In 2010 it was 60 times greater than national rate. objective Taima (translates to "stop" Inuktitut) TB study implement and evaluate public health campaign enhance existing prevention efforts Nunavut. Methods A awareness followed by door-to-door screening carried out Iqaluit, aim raise about TB, provide in-home treatment for people living...
Background Tuberculosis (TB) remains a significant health burden among Inuit in Canada. Social determinants of (SDH) play key role TB infection, disease and ongoing transmission this population. The objective research was to estimate the prevalence social as they relate latent infection (LTBI) people living residential areas at high risk for Iqaluit, Nunavut. Methods Inperson home surveys were conducted those who lived predetermined identified door-to-door prevention campaign Nunavut 2011....