A5036627769- Tuberculosis Research and Epidemiology
- HIV/AIDS Research and Interventions
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- HIV/AIDS Impact and Responses
- HIV, Drug Use, Sexual Risk
- Antibiotic Use and Resistance
- HIV/AIDS drug development and treatment
- Adolescent Sexual and Reproductive Health
- Global Maternal and Child Health
- Mental Health Treatment and Access
- Healthcare Systems and Reforms
- HIV Research and Treatment
- Infectious Diseases and Tuberculosis
- Pharmaceutical Practices and Patient Outcomes
- Patient Satisfaction in Healthcare
- Mycobacterium research and diagnosis
- Primary Care and Health Outcomes
- Participatory Visual Research Methods
- Interprofessional Education and Collaboration
- Health Policy Implementation Science
- Global Health and Surgery
- Mobile Health and mHealth Applications
- COVID-19 diagnosis using AI
- Mental Health and Patient Involvement
Centre for Global Health Research
2020-2025
York University
2019-2025
Centre for the AIDS Programme of Research in South Africa
2015-2024
University of KwaZulu-Natal
2014-2024
South African Medical Research Council
2016-2024
McGill University
2016-2022
University of Toronto
2007-2022
Public Health Ontario
2015-2022
McGill University Health Centre
2016-2020
Columbia University
2012-2017
Background: mHealth is a promising means of supporting adherence to treatment. The Start TB patients on ART and Retain Treatment (START) study included real-time support using short-text messaging service (SMS) text trained village health workers (VHWs). We describe the use acceptability by with HIV/tuberculosis care providers. Methods: Patients treatment supporters received automated, coded medication appointment reminders at their preferred time frequency, own phones, $3.70 in monthly...
Determining whether antibiotic prescriptions are inappropriate requires knowledge of patients' underlying conditions. In low-income and middle-income countries (LMICs), where misdiagnoses frequent, this is challenging. Additionally, such details often unavailable for prescription audits. Recent studies using standardised patients (SPs) offer a unique opportunity to generate unbiased prevalence estimates overuse, as the research design involves with predefined conditions.Secondary analyses...
Background One-fifth of the patients on multidrug-resistant tuberculosis treatment at Drug-Resistant-TB (DR-TB) Site in Gujarat are lost-to-follow-up(LFU). Objective To understand patients’ and providers' perspectives reasons for LFU their suggestions to improve retention-in-care. Design Qualitative study conducted between December 2013-March 2014, including in-depth interviews with DOT-providers, a focus group discussion DR-TB site supervisors. A thematic-network analysis approach was...
Despite renewed focus on molecular tuberculosis (TB) diagnostics and new antimycobacterial agents, treatment outcomes for patients co-infected with drug-resistant TB human immunodeficiency virus (HIV) remain dismal, in part due to lack of medication adherence as a patient-centered continuum care.To review current barriers TB-HIV propose an alternative model conventional approaches support.Current national control programs rely heavily directly observed therapy (DOT) the centerpiece delivery...
Adherence to antiretroviral therapy (ART) and second-line antituberculosis medications is essential achieve successful outcomes among individuals co-infected with HIV multi or extensively drug-resistant TB (M/XDR-TB). In 2012-2013, we designed a qualitative study explore barriers adherence in KwaZulu-Natal, South Africa. We conducted six focus groups comprising 23 adults receiving treatment for either MDR-TB (n = 2) XDR-TB 21); 17 were on concurrent ART. Participants expressed preference ART...
The introduction of Bedaquiline, the first new antimycobacterial drug in over 40 years, has highlighted critical importance medication adherence drug-resistant tuberculosis (DR-TB) treatment to prevent amplified drug-resistance and derive sustained benefit. Real-time electronic dose monitoring (EDM) accurately measures allows for titration support anti-retroviral therapy (ART). goal this study was evaluate accuracy acceptability a next-generation pillbox (Wisepill RT2000)...
Tuberculosis (TB) remains an enormous public health concern globally. India and South Africa rank among the top 10 high TB burden countries with highest absolute of TB, second rate incidence, respectively. Although primary drivers transmission vary considerably between these two countries, they do indeed share common themes. In 2017, only 64% global estimated incident cases were reported, remaining 36% 'missing' either undiagnosed, untreated or unreported. These 'missing cases' have...
Abstract In South Africa, more than 60% of TB patients have HIV co-infection. Voluntary counseling and testing (VCT) is critical to effective prevention, facilities are optimal venues for delivery these services. This study employed qualitative research methods explore the decision-making processes serostatus disclosure by 21 hospitalized with multi/extensively-drug resistant (M/XDR-TB) in Durban, KwaZulu Natal. Data collected from in-depth interviews characterized 3 broad themes: history,...
Abstract There is a growing imperative to improve the coordination and collaboration of tuberculosis (TB) HIV healthcare services in response escalating rates TB/HIV coinfection. Patient-specific challenges associated with delivery care have been minimally explored this regard. As part larger study conducted South Africa, article highlights coinfected patients' experiences TB light their broader social environments. Qualitative, in-depth interviews were 40 adult, patients (24 women 16 men)...
BackgroundThere is little evidence of patient acceptability for drug-resistant tuberculosis (DRTB) care in the context new treatment regimens and HIV co-infection. We aim to describe experiences DRTB-HIV among patients KwaZulu-Natal province, South Africa.MethodsIn this qualitative study using Bury's framework chronic illness, we conducted 13 focus groups at a tertiary hospital with 55 co-infected DRTB (28 women, 27 men) who were receiving bedaquiline-based DRTB, concurrent antiretroviral...
India has the world's highest burden of tuberculosis (TB). Private retail pharmacies are preferred provider for 40% patients with TB symptoms and up to 25% diagnosed patients. Engaging in screening services could improve case detection.A novel referral intervention was piloted over 18 months, under pragmatic staggered recruitment 105 Patna, India. The integrated into an ongoing public-private mix (PPM) programme, five added components: pharmacy training screening, a chest radiograph (CXR)...
There has been much speculation during the past week about catastrophe that awaits once coronavirus disease 2019 (COVID-19) establishes itself in poorest communities of South Africa (SA) and, importantly, informal settlements. Evidence to date suggests COVID-19 is efficiently passed from infected individuals via large droplets and hard-surface fomites.