A5044691342- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Tuberculosis Research and Epidemiology
- Pneumonia and Respiratory Infections
- Pneumocystis jirovecii pneumonia detection and treatment
- Respiratory Support and Mechanisms
- Long-Term Effects of COVID-19
- Global Cancer Incidence and Screening
- Head and Neck Cancer Studies
- Lung Cancer Research Studies
- Pleural and Pulmonary Diseases
- Pancreatic and Hepatic Oncology Research
- Occupational and environmental lung diseases
- COVID-19 Clinical Research Studies
- Esophageal Cancer Research and Treatment
- Lymphoma Diagnosis and Treatment
- Drug-Induced Ocular Toxicity
- Viral-associated cancers and disorders
- Radiology practices and education
- Vascular Anomalies and Treatments
- Lipoproteins and Cardiovascular Health
- Gastric Cancer Management and Outcomes
- Ferroptosis and cancer prognosis
McGill University Health Centre
2012-2024
McGill University
2014-2024
Jewish General Hospital
2024
Nunavik Regional Board of Health and Social Services
2024
St. Michael's Hospital
2024
University of British Columbia
2024
University of Ottawa
2024
University of Calgary
2024
University of Toronto
2024
University of Saskatchewan
2024
Many persons with chronic obstructive pulmonary disease (COPD) or asthma have not received a diagnosis, so their respiratory symptoms remain largely untreated.
Limited resection has been increasingly used in older patients with stage IA lung cancer. However, the equivalency of limited versus lobectomy according to histology is unknown.We identified than 65 years invasive adenocarcinoma or squamous cell carcinoma ≤ 2 cm who were treated (wedge segmentectomy) Surveillance, Epidemiology, and End Results-Medicare database. We estimated propensity scores that predicted use compared survival lobectomy. Treatments considered equivalent if upper 95th...
Abstract Objective To determine if inhaled and intranasal ciclesonide are superior to placebo at decreasing respiratory symptoms in adult outpatients with covid-19. Design Randomised, double blind, controlled trial. Setting Three Canadian provinces (Quebec, Ontario, British Columbia). Participants 203 adults aged 18 years older polymerase chain reaction confirmed covid-19, presenting fever, cough, or dyspnoea. Intervention were randomised receive either (600 μg twice daily) (200 metered dose...
Previous trials have demonstrated the effects of fluvoxamine alone and inhaled budesonide for prevention disease progression among outpatients with COVID-19. To determine whether combination would increase treatment in a highly vaccinated population. Randomized, placebo-controlled, adaptive platform trial. (ClinicalTrials.gov: NCT04727424). 12 clinical sites Brazil. Symptomatic adults confirmed SARS-CoV-2 infection known risk factor to severe disease. Patients were randomly assigned either...
Rationale: A significant proportion of individuals with chronic obstructive pulmonary disease (COPD) and asthma remain undiagnosed. Objectives: The objective this study was to evaluate symptoms, quality life, healthcare use, work productivity in subjects undiagnosed COPD or compared those previously diagnosed, as well healthy control subjects. Methods: This multicenter population-based case-finding randomly recruited adults respiratory symptoms who had no previous history diagnosed lung from...
Advances in molecular biology are improving the understanding of lung cancer and changing approach to treatment. A satisfactory biopsy that allows for histologic characterization mutation analysis is becoming increasingly important. Most patients with diagnosed at an advanced stage, diagnosis often based on a small or cytology specimen. Here, we review techniques available making cancer, including bronchoscopy, ultrasound-guided mediastinoscopy, transthoracic needle aspiration,...
Video-assisted thoracoscopic surgery (VATS) and open lobectomy are both standard of care for the treatment early-stage non-small cell lung cancer (NSCLC) because equivalent long-term survival.To evaluate whether improved perioperative outcomes associated with VATS explained by surgeon characteristics, including case volume specialty training.We analyzed Surveillance, Epidemiology, End Results-Medicare-linked registry to identify stage I-II NSCLC in patients above 65 years age. We used a...
Background: Racial disparities in resection of non–small cell lung cancer (NSCLC) are well documented. Patient-level and system-level factors only partially explain these findings. Although physician-related have been suggested as mediators, empirical evidence for their contribution is limited. Objective: To determine if racial receipt thoracic surgery persisted after patients had a surgical consultation whether there was physician to care. Methods: The authors identified 19,624 with stage...
This study described the participation in daily and social activities perceived barriers facilitators to of individuals with chronic obstructive pulmonary disease (COPD). Individuals, recruited from outpatient clinics, responded a survey on their in, towards, 26 activities, divided into 3 categories: (1) physical activity movement (PAM); (2) self-care; (3) engagement. For each activity, chi-square analyses were used examine differences by individuals': quartiles airflow obstruction [percent...
Introduction: Lung cancer is the most common worldwide in mortality and second incidence. Epidemiological studies found a higher lung risk for smoking women comparison to men, but these sex differences, irrespective of habits, remains controversial. One hypotheses concerns genetic contribution chromosomes. However, while genomewide association identified many susceptibility loci, analyses have excluded X-linked loci. Methods: To account non-genetic factors, we first presented an test based...
Abstract Background Pneumocystis jirovecii pneumonia (PJP) can be challenging to diagnose, often requiring bronchoscopy. Since most patients suspected of PJP undergo imaging, we hypothesized that the findings these studies could help estimate probability disease prior invasive testing. Methods We created a cohort who underwent bronchoscopy specifically diagnose and conducted nested case-control study compare radiographic features between with ( n = 72) without 288) pathologically proven PJP....
It remains unclear why some symptomatic individuals with asthma or COPD remain undiagnosed. Here, we compare patient and physician characteristics between obstructive lung disease (OLD) who are undiagnosed physician-diagnosed OLD.Using random-digit dialling population-based case finding, recruited 451 participants OLD 205 control OLD. Data on symptoms, quality of life healthcare utilisation were analysed. We surveyed family physicians in both groups to elucidate differences practices that...
Guidelines recommend timely evaluation of patients with suspected lung cancer. We evaluated the impact a Rapid Investigation Clinic (RIC) on timeliness cancer diagnosis and treatment between February 2010 December 2011.Investigation within RIC was conducted by pulmonologist nurse clinician. Controls were cancer, investigated outside at same institution during time period. The primary outcome first contact local physician for (T0) treatment. Factors associated delay from T0 to examined using...
Introduction Pneumocystis jirovecii pneumonia (PJP) is an opportunistic infection of immunocompromised hosts with significant morbidity and mortality. The current standard care, trimethoprim-sulfamethoxazole (TMP-SMX) at a dose 15–20 mg/kg/day, associated serious adverse drug events (ADE) in 20%–60% patients. ADEs include hypersensitivity reactions, drug-induced liver injury, cytopenias renal failure, all which can be treatment limiting. In recent meta-analysis observational studies, reduced...