A5087361969- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Respiratory Support and Mechanisms
- Pediatric health and respiratory diseases
- Health Systems, Economic Evaluations, Quality of Life
- Respiratory and Cough-Related Research
- Obstructive Sleep Apnea Research
- Pleural and Pulmonary Diseases
- Neuroscience of respiration and sleep
- Global Cancer Incidence and Screening
- Clinical practice guidelines implementation
- Inhalation and Respiratory Drug Delivery
- Occupational and environmental lung diseases
- Lung Cancer Diagnosis and Treatment
- Musculoskeletal pain and rehabilitation
- Simulation-Based Education in Healthcare
- Delphi Technique in Research
- Smoking Behavior and Cessation
- Ultrasound in Clinical Applications
- Sleep and related disorders
- Healthcare cost, quality, practices
- Chronic Disease Management Strategies
- Tracheal and airway disorders
- Agriculture and Farm Safety
- Economic and Financial Impacts of Cancer
University of Saskatchewan
2016-2025
St. Michael's Hospital
2024
University of British Columbia
2024
University of Ottawa
2024
McGill University
2024
University of Calgary
2008-2024
University of Toronto
2021-2024
Université Laval
2024
University of Alberta
2024
Western University
2024
Many persons with chronic obstructive pulmonary disease (COPD) or asthma have not received a diagnosis, so their respiratory symptoms remain largely untreated.
The use of prophylactic radiotherapy to prevent procedure-tract metastases (PTMs) in malignant pleural mesothelioma remains controversial, and clinical practice varies worldwide. We aimed compare with deferred (given only when a PTM developed) suitably powered trial.We did multicentre, open-label, phase 3, randomised controlled trial 22 UK hospitals patients histocytologically proven who had undergone large-bore interventions the 35 days prior recruitment. Eligible were (1:1), using...
Expert national/global asthma management recommendations raise the issue whether a safe threshold of short-acting beta-2 agonist (SABA) use without concomitant inhaled corticosteroids (ICS) exists.To examine SABA and maintenance therapy associations with severe exacerbations across North America Europe.Observational analyses 10 SABa IN Asthma (SABINA) datasets involving 1,033,564 patients (≥12 y) from Canada, France, Netherlands, Poland, Spain, United Kingdom, States. Negative binomial...
ABSTRACT Background and objective Malignant pleural effusion is associated with morbidity mortality. A randomized controlled trial previously compared clinical outcomes resource use indwelling catheter ( IPC ) talc pleurodesis in this population. Using unpublished quality of life data, we estimate the cost‐effectiveness pleurodesis. Methods Healthcare utilization costs were captured during trial. Utility weights produced by EuroQol Group five‐dimensional three‐level questionnaire survival...
Rationale: A significant proportion of individuals with chronic obstructive pulmonary disease (COPD) and asthma remain undiagnosed. Objectives: The objective this study was to evaluate symptoms, quality life, healthcare use, work productivity in subjects undiagnosed COPD or compared those previously diagnosed, as well healthy control subjects. Methods: This multicenter population-based case-finding randomly recruited adults respiratory symptoms who had no previous history diagnosed lung from...
Abstract Objective The aim of the present study was to evaluate whether rheumatoid arthritis (RA) patients followed longitudinally using video‐conferencing and inter‐professional care support have comparable disease control those in traditional in‐person rheumatology clinics. Methods This a randomized controlled trial for 85 RA allocated either follow‐up or video‐conferenced with urban‐based rheumatologists rural physical therapist examiners. Follow‐up every 3 months 9 months. Outcome...
Chronic obstructive pulmonary disease (COPD) has substantial economic and human costs; it is expected to be the third leading cause of death worldwide by 2030. To minimize these costs high quality guidelines have been developed. However, alone rarely result in meaningful change. One method integrating into practice use clinical pathways (CPWs). CPWs bring available evidence a range healthcare professionals detailing essential steps care adapting local context. We are working with...
Background ∼5–10% of adults may have undiagnosed airflow obstruction. The objective this study was to develop a population-based case-finding strategy assess the prevalence obstruction (asthma or COPD) amongst with respiratory symptoms in Canada. Methods Adults without previous history asthma, COPD lung disease were recruited using random digit-dialling and asked if they had dyspnoea, cough, sputum wheeze within past 6 months. Those who answered affirmatively completed Asthma Screening...
Obstructive sleep apnea is a common condition within the Canadian population. The current gold standard for diagnosis and management of patients in-laboratory (in-lab) polysomnography; however, limited availability testing options has led to long wait times increased disease burden Sleep Research Laboratory in Saskatoon (Saskatchewan) implemented home program run parallel with in-lab system several years ago an effort increase their capacity reduce times. present study was retrospective...
Background Patients with asthma use short-acting β-agonists (SABA) to relieve symptoms but SABA alone does not treat underlying inflammation. Thus, over-reliance on may result in poor control and negative health outcomes. Objective To describe of characterise the relationship severe exacerbations Canadian provinces Nova Scotia (NS) Alberta (AB). Methods In this longitudinal Asthma (SABINA) study, patients an diagnosis were identified between 2016 2020 within two provincial administrative...
Chronic obstructive pulmonary disease (COPD) patient care must include confirming a diagnosis with postbronchodilator spirometry. Because of the clinical heterogeneity and reality that airflow obstruction assessed by spirometry only partially reflects severity, thorough evaluation should assessment symptom burden risk exacerbations permits implementation evidence-informed pharmacological nonpharmacological interventions. This guideline provides recommendations from comprehensive systematic...
<h3>Importance</h3> Sleep-disordered breathing (SDB) is common and associated with substantial adverse health consequences. Long wait times for SDB care are commonly reported; however, it unclear whether clinical outcomes. <h3>Objective</h3> To evaluate the association of outcomes patients severe SDB. <h3>Design, Setting, Participants</h3> This study a secondary analysis randomized noninferiority trial comparing management by alternative practitioners (ACPs) traditional sleep physician–led...
This position statement aims to provide guidance for resumption of pulmonary rehabilitation (PR) services during the post-peak phase COVID-19 pandemic (ie, period low community prevalence...
RATIONALE: There is a need to characterize the real-world impact of benralizumab, an anti-interleukin-5 receptor alpha antibody, for add-on maintenance therapy patients with severe eosinophilic asthma.