Gatha Adhikari

ORCID: 0000-0002-3832-8832
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About
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Research Areas
  • 3D Printing in Biomedical Research
  • Advanced Radiotherapy Techniques
  • Nanoparticle-Based Drug Delivery
  • Anatomy and Medical Technology
  • Optical Imaging and Spectroscopy Techniques
  • Cancer Cells and Metastasis

University of Maryland, College Park
2023-2024

Local drug delivery aims to minimize systemic toxicity by preventing off-target effects; however, injection parameters influencing depot formation of injectable gels have yet be thoroughly studied. We explored the effects needle characteristics, depth, rate, volume, and polymer concentration on gel ethanol distribution in both tissue phantoms.

10.1109/tbme.2023.3340613 article EN IEEE Transactions on Biomedical Engineering 2023-12-07

Abstract Cervical cancer, the second leading cause of cancer-related death for women worldwide, remains a preventable yet persistent disease that disproportionately affects in low and middle-income countries (LMICs). While existing therapies treating cervical dysplasia are effective, they often inaccessible LMICs. Ethanol ablation is an alternative low-cost, accessible therapy we previously enhanced into ethyl cellulose (EC)-ethanol gel formulation to improve efficacy. When seeking evaluate...

10.1101/2024.02.20.581242 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-02-23

Introduction: Cervical cancer, the second leading cause of cancer-related death for women worldwide, remains a preventable yet persistent disease that disproportionately affects in low and middle-income countries (LMICs). While existing therapies treating cervical dysplasia are effective, they often inaccessible LMICs. Ethanol ablation is an alternative low-cost, accessible therapy we previously enhanced into ethyl cellulose (EC)-ethanol gel formulation to improve efficacy. Methods: To...

10.3389/fbiom.2024.1365781 article EN cc-by Frontiers in Biomaterials Science 2024-05-09
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