Abstract Purpose To enable a real‐time applicator guidance for brachytherapy, we used the first time infra‐red tracking cameras (OptiTrack, USA) integrated into mobile cone‐beam computed tomography (CBCT) scanner (medPhoton, Austria). We provide description of this prototype and its performance evaluation. Methods performed assessments camera calibration camera‐CBCT registration using geometric phantom. For purpose, evaluated effects intrinsic parameters such as temperature or gantry...

On-site cone-beam computed tomography (CBCT) has gained in importance adaptive brachytherapy during recent years. Besides treatment planning, there is increased need particularly for image-guidance interventional procedures and image-guided quality assurance (QA). For this purpose, an innovative CBCT device was rolled out at our hospital as the first site worldwide. We present clinical images experiences.The novel system constructed of a 121 cm diameter ring gantry, features 43.2 × cm2...

Abstract Purpose Needle tracking using external prediction techniques such as optical is a modern approach aimed at improving implantation accuracy in gynecologic brachytherapy. This study aims to investigate the corresponding impact of needle bending situ and analyze path deviations from intended locations occurring our current clinical workflow that only considers ultrasound imaging without tracking. Methods We developed semi-automated for reconstructing brachytherapy needles based on...

Abstract Purpose This study evaluates the technical feasibility of adapting a surface monitoring system, designed for conventional four‐dimensional computed tomography (4DCT), to an intelligent, breathing‐adapted 4DCT and examines its potential expand currently limited range supported surrogate systems. Methods In experimental phantom setting, we compared breathing curve quality impact on generation between camera our clinical infrared (IR) using research‐grade IR coupled with radiation...

Background and purpose In the brachytherapy of cervical cancer, creating a suitable implant based on ultrasound guidance may be impacted by imaging limitations. To validate if is not sufficient, we implemented new workflow utilizing additional intraoperative cone-beam computed tomography (CBCT). The aims this work were to describe newly established workflow, reflect associated (dis)advantages, assess geometric dosimetric benefits compared previous solely ultrasound-guided workflow. Materials...

A novel, mobile cone-beam computed tomography (CBCT) system for image-guided adaptive brachytherapy was recently deployed at our hospital as worldwide first site. Prior to the device's clinical operation, a profound characterization of its imaging performance conducted. This essential optimize both workflow and image quality achieving best possible outcomes. We present results investigations.The novel CBCT-system features ring gantry with 121 cm clearance well 43.2 × cm2 flat-panel detector,...

Abstract Purpose A prototype infrared camera – cone-beam computed tomography (CBCT) system for tracking in brachytherapy has recently been developed. We evaluated the first time corresponding accuracy and uncertainties, implemented a tracking-based prediction of needles on CBCT scans. Methods marker tool rigidly attached to was 3D printed. The precision then both static dynamic scenarios. Euclidean distances between tracked CBCT-derived markers were assessed as well. To implement needle...

The regular evaluation of imaging performance computed tomography (CT) scanners is essential for CT quality assurance. For automation this process, the software QAMaster was developed at Universitätsklinikum Erlangen, which provides based on scans CatPhan® 504 (The Phantom Laboratory, Salem, USA) automated image analysis and documentation by evaluating number accuracy, spatial linearity, uniformity, contrast-noise-ratio, resolution, noise, slice thickness. Dose assessment supported...

Abstract Background Failure mode and effects analysis (FMEA) is a valuable tool for radiotherapy risk assessment, yet its outputs might be unreliable due to failures not being identified or lack of accurate error rates. Purpose A novel incident reporting system (IRS) linked an FMEA database was tested evaluated. The study investigated whether the suitable validating previously performed it could provide rates support expert occurrence ratings failure modes. Methods Twenty‐three...

Purpose To enable a fast and automatic deep learning–based QSM reconstruction of tissues with diverse chemical shifts, relevant to most regions outside the brain. Methods A UNET was trained reconstruct susceptibility maps using synthetically generated, unwrapped, multi‐echo phase data as input. The RMS error respect synthetic validation computed. method tested on two in vivo knee pelvis sets. Comparisons were made conventional fat–water separation pipeline by applying commonly used graph‐cut...

A novel, mobile 3-in-1 X-ray system featuring radiography, fluoroscopy, and cone-beam computed tomography (CBCT) has been launched for brachytherapy recently. Currently, there is no quality assurance (QA) procedure explicitly applicable to this equipped with innovative technologies such as dynamic jaws motorized lasers. We developed a dedicated QA and, based on its performance duration of 6 months, provide an assessment the device's stability over time.With procedure, we assessed system's...

Four-dimensional computed tomography (4DCT) scans are standardly used for radiotherapy planning of tumors subject to respiratory motion. Based on online analysis and automatic adaption scan parameters the patient's individual breathing pattern, a new breathing-controlled 4DCT (i4DCT) algorithm attempts counteract irregular thus prevent artifacts. The aim this study was perform an initial quality assurance i4DCT.To validate i4DCT algorithm, phantom measurements were performed evaluate...

Abstract Background and purpose Model-based dose calculation considering tissue compositions is increasingly being investigated in brachytherapy. The aim of this study was to assess the suitability modern cone-beam computed tomography (CBCT) imaging compared conventional (CT) scans for purpose. Materials methods By means a phantom study, we evaluated CT numbers electron densities measured using CBCT device as well scanner various materials. Based on this, calculations (using TG-43 formalism...

CBCT imaging with field of views (FOVs) exceeding the size scans acquired in conventional geometry, i.e. opposing source and detector, is high clinical importance for many medical fields. A novel approach enlarged FOV scanning one full-scan (EnFOV360) or two short-scans (EnFOV180) using an O-arm system arises from non-isocentric based on independent detector rotations.The presentation, description, experimental validation this techniques EnFOV360 EnFOV180 forms scope work.We describe...

Background and purposeEven with most breathing-controlled four-dimensional computed tomography (4DCT) algorithms image artifacts caused by single significant longer breathing still occur, resulting in negative consequences for radiotherapy. Our study presents first phantom examinations of a new optimized raw data selection binning algorithm, aiming to improve quality geometric accuracy without additional dose exposure.Materials methodsTo validate the approach, measurements were performed...

Abstract Objective There are numerous curative treatment possibilities for prostate cancer. In patients who have undergone rectal extirpation cancer treatment, options limited due to anatomic changes and previous irradiation of the pelvis. this analysis, we validate feasibility CT-guided transperineal interstitial brachytherapy specific scenario. Patients methods We analyzed procedures outcomes 5 with metachronic nonmetastatic Ultrasound-guided was not possible in any patients. Of these...

To assess the effects of a workflow for reproducible patient and breast positioning on implant stability during high-dose-rate multi-catheter brachytherapy.

Interstitial and/or intracavitary brachytherapy is an integral part of the treatment vaginal cancer Brachytherapy (BT) has shown to improve local control, overall survival (OS) and disease-free (DFS). The aim our study was analyze efficacy safety in patients with cancer.

Low-dose-rate (LDR) brachytherapy with I-125 seeds is one of the most common primary tumor treatments for low-risk and low-intermediate-risk prostate cancer. This report aimed to present an analysis single-institution long-term results. We analyzed treatment outcomes 119 patients low- intermediate-risk cancer treated LDR at our institution between 2014 2020. The focused on biochemical recurrence rates (BRFS), overall survival (OS), cumulative local rate (CLRR), incidence acute late...