A5000020918- Advanced Radiotherapy Techniques
- Radiation Dose and Imaging
- Polysaccharides and Plant Cell Walls
- Medical Imaging Techniques and Applications
- Surgical Simulation and Training
- Breast Cancer Treatment Studies
- Ultrasound Imaging and Elastography
- AI in cancer detection
- Microfluidic and Bio-sensing Technologies
- Skin and Cellular Biology Research
- Advanced X-ray and CT Imaging
- Wnt/β-catenin signaling in development and cancer
- Force Microscopy Techniques and Applications
- Cellular Mechanics and Interactions
- Digital Radiography and Breast Imaging
- Medical Imaging and Analysis
- Wireless Body Area Networks
- MRI in cancer diagnosis
- Spinal Fractures and Fixation Techniques
- Dental Implant Techniques and Outcomes
- Breast Implant and Reconstruction
- Breast Lesions and Carcinomas
Friedrich-Alexander-Universität Erlangen-Nürnberg
2019-2024
Comprehensive Cancer Center Erlangen
2022-2024
Universitätsklinikum Erlangen
2022-2024
Centre hospitalier de l'Université Laval
2024
Université Laval
2024
Plectin, a highly versatile cytolinker protein, provides tissues with mechanical stability through the integration of intermediate filaments (IFs) cell junctions. Here, we hypothesize that plectin-controlled cytoarchitecture is critical determinant intestinal barrier function and homeostasis. Mice lacking plectin in an epithelial (IEC; PleΔIEC) spontaneously developed colitis characterized by extensive detachment IECs from basement membrane (BM), increased permeability, inflammatory lesions....
Abstract Background Electromagnetic tracking (EMT) systems have proven to be a valuable source of information regarding the location and geometry applicators in patients undergoing brachytherapy (BT). As an important element enhanced individualized pre‐treatment verification, EMT can play pivotal role detecting treatment errors uncertainties increase patient safety. Purpose The purpose this study is two‐fold: design, develop test dedicated measurement protocol for use EMT‐enabled...
Abstract Background Failure mode and effects analysis (FMEA) is a valuable tool for radiotherapy risk assessment, yet its outputs might be unreliable due to failures not being identified or lack of accurate error rates. Purpose A novel incident reporting system (IRS) linked an FMEA database was tested evaluated. The study investigated whether the suitable validating previously performed it could provide rates support expert occurrence ratings failure modes. Methods Twenty‐three...
Electromagnetic tracking (EMT) is a versatile and viable technique for various quality assurance (QA) tasks in interstitial brachytherapy (iBT). As the duration of EMT measurements iBT on order minutes, they can be strongly affected by patient motion, especially breathing, which gives rise to motion artefacts. Since centrepiece EMT-related QA assess geometry implant or applicator, absence adequate compensation techniques could impede use purposes. A common way compensate this reference data...
Electromagnetic tracking (EMT) is a promising technology that holds great potential to advance patient-specific pre-treatment verification in interstitial brachytherapy (iBT). It allows easy determination of the implant geometry without line-of-sight restrictions and dose exposure patient. What it cannot provide, however, link anatomical landmarks, such as exit points catheters or needles on skin surface. These landmarks are required for registration EMT data with other imaging modalities...
Abstract Background Electromagnetic tracking (EMT) has been researched for brachytherapy applications, showing a great potential automating implant reconstruction, and overcoming image‐based limitations such as contrast spatial resolution. One of the challenges this technology is that it does not intrinsically share same reference frame patient's medical imaging. Purpose To present novel phantom can be used comprehensive quality assurance (QA) program EMT systems use to validate...
Electromagnetic tracking (EMT) has great potential as a quality assurance tool in interstitial brachytherapy. Since its clinical application most cases comprises comparison with brachytherapy plan data, EMT registration and data are crucial. Registration uncertainties influence outcomes further decision-making processes. The impact of using four algorithms on the resulting was investigated.
Electromagnetic tracking (EMT) systems have been shown to provide valuable information on the geometry of catheter implants in breast cancer patients undergoing interstitial brachytherapy (iBT). In context an extended patient-specific, pre-treatment verification, EMT can play a key role determining potential need and, if applicable, appropriate time for treatment adaptation. To detect dosimetric shortcomings relative position between catheters, and target volume critical structures must be...
ABSTRACT Plectin, a highly versatile cytolinker protein, provides tissues with mechanical stability through the integration of intermediate filaments (IFs) cell junctions. Here, we hypothesize that plectin-controlled cytoarchitecture is critical determinant intestinal barrier function and homeostasis. Mice lacking plectin in epithelial cells (IEC; Ple ΔIEC ) spontaneously developed colitis characterized by extensive detachment IECs from basement membrane (BM), increased permeability,...
ABSTRACT Magnetic tweezers based on solenoids with iron alloy cores are widely used to apply large forces (~100 nN) onto micron-sized (~5 μ m) superparamagnetic particles for mechanical manipulation or microrheological measurements at the cellular and molecular level. The precision of magnetic tweezers, however, is limited by hysteresis core material, especially time-varying force protocols. Here, we eliminate a feedback control induction, which measure Hall sensor mounted distal end...
Electromagnetic tracking (EMT) shows great potential for automating implant reconstruction in brachytherapy. One of the challenges this technology is that it does not intrinsically share same reference frame as patient's medical imaging. The purpose work to register frames an EMT-enabled afterloader and a CT scan image rigid phantom quality control EMT-based reconstruction. geometry twelve 6F catheters tandem ring gynecological applicator were reconstructed using EMT sensor attached...