A5086342390- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Inflammatory Myopathies and Dermatomyositis
- Chronic Lymphocytic Leukemia Research
- Systemic Lupus Erythematosus Research
- Systemic Sclerosis and Related Diseases
- Dermatological and COVID-19 studies
- Voice and Speech Disorders
- Biosimilars and Bioanalytical Methods
- Tuberculosis Research and Epidemiology
- Musculoskeletal pain and rehabilitation
- Temporomandibular Joint Disorders
- Spondyloarthritis Studies and Treatments
- Healthcare during COVID-19 Pandemic
- Lymphoma Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Herpesvirus Infections and Treatments
- Oral Health Pathology and Treatment
- Leprosy Research and Treatment
- Myofascial pain diagnosis and treatment
- Immunodeficiency and Autoimmune Disorders
- Skin Diseases and Diabetes
- Hematological disorders and diagnostics
- Psoriasis: Treatment and Pathogenesis
Universidade Federal de Sergipe
2012-2023
UniBrasil Centro Universitário
2016
Centro Hospitalar do Tâmega e Sousa
2010-2014
Universidade Federal do Rio de Janeiro
1992
Objective The objective of this study was to determine the frequency signs and symptoms temporomandibular disorder (TMD) in fibromyalgic patients. Methods Sixty subjects both sexes (mean age, 49.2 ± 13.8 years) with fibromyalgia (FM) diagnosis were included study. All patients examined by a calibrated investigator identify presence TMD using Research Diagnostic Criteria for TMD. Results most common (A) (B) reported FM pain masticatory muscles (masseter, 80%; posterior digastric, 76.7%),...
To assess the incidence of tuberculosis and to screen for latent infection among Brazilians with rheumatoid arthritis using biologics in clinical practice. This cohort study used data from Brazilian Registry Biological Therapies Rheumatic Diseases (Registro Brasileiro de Monitoração Terapias Biológicas – BiobadaBrasil), 01/2009 05/2013, encompassing 1552 treatments, including 415 only synthetic disease-modifying anti-rheumatic drugs, 942 DMARDs combined anti-tumor necrosis factor...
Avaliar incidência de tuberculose e triagem para latente em brasileiros com artrite reumatoide uso agentes biológicos na prática clinica. Estudo coorte dados do Registro Brasileiro Monitoração Terapias Biológicas (BiobadaBrasil), 01/2009 a 05/2013, abrangeu 1.552 tratamentos, 415 somente drogas modificadoras curso da doença (MMCDs) sintéticas, 942 MMCDs sintéticas associação anti‐TNF (etanercepte, infliximabe, adalimumabe) 195 outros (abatacepte, rituximabe tocilizumabe). Avaliaram‐se...
Este estudo teve como objetivo identificar a frequência de sintomas ansiosos e depressivos verificando associação entre ansiedade-traço, atuais depressão ansiedade nos fibromiálgicos. Foram entrevistados 60 sujeitos com diagnóstico fibromialgia no Ambulatório Reumatologia da Universidade Federal Sergipe, agosto 2007 março 2008, sendo aplicados dois questionários: Escala Hospitalar Ansiedade Depressão (EHAD) o Inventário Traço-Estado (IDATE-T). A foi, respectivamente, 50% 86% para os...
The safety profile of biologic drugs might present substantial regional differences. Since 2009, the Brazilian Society Rheumatology has maintained BIOBADABRASIL (Brazilian Registry for Biologic Drugs), a registry monitoring therapies in rheumatic diseases.The aim this study was to verify incidence rate (IR) serious infections rheumatoid arthritis (RA) and spondyloarthritis (SpA) patients on drugs.BIOBADABRASIL prospectively included with diseases who started first drug or synthetic...
Objective. To evaluate the safety of methotrexate (MTX)–leflunomide (LEF) combination in rheumatoid arthritis (RA), comparing it with other therapeutic schemes involving conventional synthetic (cs-) and biologic (b-) disease-modifying antirheumatic drugs (DMARDs) or Janus kinase inhibitors (JAKi). Methods. Patients RA starting a treatment course csDMARD (without previous use bDMARD JAKi) their first bDMARD/JAKi were followed up registry-based, multicentric cohort study Brazil...
Abstract Objectives To test the association of use antimalarials with overall safety treatment in RA patients receiving one or multiple courses biologic (b)DMARDs a Janus kinase inhibitor (JAKi). Methods BiobadaBrasil is multicentric registry-based cohort study Brazilian rheumatic diseases starting their first bDMARD JAKi. The present analysis includes recruited from January 2009 to October 2019, followed up over (up six) (latest date, 19 November 2019). primary outcome was incidence serious...
RESUMO A Esclerose Sistêmica é uma doença reumática autoimune do tecido conjuntivo, progressiva, pouco frequente, de etiologia desconhecida e com evolução variável. Atinge órgãos nobres tecidos periorais, causando limitação na abertura da boca, hipertonia dos fonoarticulatórios, face "aparência máscara", dificuldades mastigação deglutição. Com o objetivo comparar os resultados pré pós-intervenção fonoaudiológica miofuncional orofacial em sujeitos esclerose sistêmica, realizou-se estudo...
<h3>Background</h3> Treatment survival of biological agents can be influenced by many factores. It seems to different between rheumatic disease. <h3>Objectives</h3> To compare the treatment disease analyze main causes discontinuation in patients with rheumatoid arthritis (RA) from Brazilian Registry – BIOBADABRASIL. <h3>Methods</h3> Cohort Society Biological Therapy Rheumatic Diseases (BIOBADABRASIL)including 2191 patients, including 1266 (57%) (RA), 678 (29.5%) spondyloarthritis 247 (12.5%)...
Apresentamos o caso de mulher com 57 anos idade apresentando polimiosite, associada a infecção pelo HTLV-I, sem manifestações clínicas acomentimento do sistema nervoso central e periférico. Fazemos alguns comentários sobre os aspectos fisiopatológicos envolvimento muscular nas infecções HTLV-I.
Gomes, Tarroso M.J.; Costa, G.; Faria, J.; Cunha, M.; A.; Macieira, J. Author Information
<h3>Background</h3> The safety profile of a-TNF drugs might have regional differences due to socio economic factors and epidemiology infectious diseases. In 2009, the Brazilian Society Rheumatology started BiobadaBrasil registry, part a Latin America project (BiobadaAmerica) with methodological support SER Biobadaser <h3>Objectives</h3> To report incidence adverse events (AE) in patients exposed Brazil <h3>Methods</h3> Since 31 centers from 21/26 states included active rheumatic diseases...
<h3>Background</h3> Herpes Zoster has been reported with increased frequency in association rheumatic diseases and biologic therapy. <h3>Objectives</h3> To study herpes zoster (HZ) patients included the Brazilian Register for monitoring of therapies - BiobadaBrasil, <h3>Methods</h3> BiobadaBrasi is a prospective observational cohort study, part an international initiative (biobadaAmerica) collaboration BiobadaSer. Patients are enrolled at moment introduction their first therapy; comparison...
Polymyositis (PM) is a systemic disease of the idiopathic inflammatory myopathy group, clinically characterized by symmetric and proximal muscle weakness. There are reports in literature PM associated with malignancies, autoimmune diseases, viral infections. However, association between nephropathy not common. We describe case report patient polymyositis who developed nephrotic syndrome due to mesangial glomerulonephritis.
<h3>Background</h3> There are few studies evaluating switching strategies of biological therapy in RA<sup>1</sup>. Survival indirect evidence treatment efficacy and safety besides being an useful tool to evaluate options the real life<sup>2</sup>. <h3>Objectives</h3> To compare survival different a second therapy. <h3>Methods</h3> Data from population-based cohort including 1,109 RA patients were analyzed at baseline (beginning first biologic therapy) up 7 years (2009–2015). Sex, age,...