Among patients with Coronavirus disease (COVID-19), the ability to identify at risk for deterioration during their hospital stay is essential effective patient allocation and management. To predict critical COVID-19 based on status admission using machine-learning models. Retrospective study a database of tertiary medical center designated departments COVID-19. Patients severe admission, low oxygen saturation, partial arterial pressure, were excluded. The primary outcome was disease, defined...

Prolonged, inappropriate hospital stay after patients' eligibility for discharge from internal medicine departments is a world-wide health-care systems' problem. Nevertheless, the extent to which such surplus stays are associated with infectious complications, their time frame of appearance and long-term implications was not previously addressed.We conducted retrospective cohort analysis patients experiencing an In-hospital Waiting Period (IHWP) in single, tertiary hospital.We screened...

Drug prescription errors are made, worldwide, on a daily basis, resulting in high burden of morbidity and mortality. Existing rule-based systems for prevention such unsuccessful associated with substantial false alerts.In this prospective study, we evaluated the accuracy, validity, clinical usefulness medication error alerts generated by novel system using outlier detection screening algorithms, used top legacy standard system, real-life inpatient setting.We integrated into an existing...

Abstract Background The task of writing multiple choice question examinations for medical students is complex, timely and requires significant efforts from clinical staff faculty. Applying artificial intelligence algorithms in this field education may be advisable. Methods During March to April 2023, we utilized GPT-4, an OpenAI application, write a 210 multi questions-MCQs examination based on existing exam template thoroughly investigated the output by specialist physicians who were...

Background: Non-small cell lung cancer (NSCLC) is a common and highly lethal disease. As advanced treatment modalities are being developed, improved prognostication methods sought. L3 skeletal muscle index (L3SMI) alanine aminotransferase (ALT) levels accepted surrogate markers of sarcopenia related frailty. We aimed to evaluate the potential association these with NSCLC patients' survival. Methods: A retrospective, single-center study an cohort. L3SMI was calculated based on area computed...

The rapid growth in diagnosed patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to national directives for hospital emergency preparedness. Sheba Medical Center, a government Israel, undertook measures expand the inpatient quarantine capacity and converted two general medical wards isolation enhanced ventilation support capabilities. Diabetes is associated increased severity, complications, mortality from disease 2019 (COVID-19) (1). care of diabetes under...

Limited information exists on causes of hospitalization in patients returning from the tropics, and most is focused febrile diseases. We evaluated all post-travel a tertiary care hospital Israel.Demographics, diagnoses, destinations admitted between January 1999 December 2003 with history recent travel were recorded. Demographics destination healthy travelers presenting to our pretravel clinic at same period recorded.Of 211 admitted, 71% males, 8% immigrants/foreign workers, diseases...

To examine the reliability of "low-risk" criteria (LRC) to exclude serious bacterial infection (SBI) in febrile neonates (< or =28 days), according age weeks.Epidemiological and clinical data final diagnosis all presenting emergency room from June 1997 May 2006 were reviewed. Neonates who fulfilled specific LRC for presence SBI classified as LRC+. The prevalence percentage LRC+ had calculated each first 4 weeks life.A total 449 evaluated. Eighty-seven (19.4%) an SBI. among infants 3-7, 8-14,...

Background. The use of vasoconstricting agents is an important part the armament used by modern medicine in treatment patients suffering from septic shock. Nevertheless, their administration associated with different severities limb ischemia. aim current study was to quantify this adverse outcome treatment. Methods. This retrospective analyzed shock, who were hospitalized a tertiary medical center. Results. Out 7,160 shock that our center over period 13 years, 4,468 eligible for analysis....

Background: Low blood ALT, Alanine aminotransferase activity and high FRAIL (Fatigue, Resistance, Ambulation, Illnesses Loss of Weight) questionnaire scores were previously shown to be associated with frailty increased risk mortality. We aimed correlate these tools mortality each other in patients hospitalized an internal medicine department. Methods: This is a prospective study large tertiary hospital. assessed the predictive value for clinical outcomes both low ALT pre-frail frail...

We aimed to investigate the prevalence of decreased folate levels in patients hospitalized with Coronavirus Disease 2019 (COVID-19) and evaluate their outcome prognostic signifi-cance associated its different levels. In this retrospective cohort study, data were obtained from electronic medical records at Sheba Medical Center. Folic acid available 333 out 1020 consecutive diagnosed COVID-19 infection January 2020 November 2020. Thirty-eight (11.4%) comprising present study population had low...

Myelodysplastic Syndrome (MDS) is a common blood dyscrasia that mainly affects the elderly population. Several prognostic scores are available utilizing count variables and cytogenetic abnormalities, targeting disease rather than patient. Sarcopenia frailty associated with shortened survival rates in various states. Low Alanine Aminotransferase (ALT) levels marker of lowered muscle mass status. This study aimed to examine correlation between low ALT prognosis MDS patients. retrospective...

Background Under- or late identification of pulmonary embolism (PE)—a thrombosis 1 more arteries that seriously threatens patients’ lives—is a major challenge confronting modern medicine. Objective We aimed to establish accurate and informative machine learning (ML) models identify patients at high risk for PE as they are admitted the hospital, before their initial clinical checkup, by using only information in medical records. Methods collected demographics, comorbidities, medications data...

<title>Abstract</title> Background. Community acquired Pneumonia (CAP) is a widespread and potentially lethal disease. Acute anemia common phenomenon featuring many such instances. However, the prevalence clinical implications of in younger CAP patients unknown. This study aimed to assess outcomes with treated modern-time (with current treatment strategies?). Methods. was retrospective analysis that were hospitalized during 2010–2024 large, tertiary medical center. Results. Following...

Patients admitted to general wards are inherently at risk of deterioration. Thus, tools that can provide early detection deterioration may be lifesaving. Frequent remote patient monitoring (RPM) has the potential allow such detection, leading a timely intervention by health care providers.This study aimed assess novel wearable RPM device alerts in patients high for deterioration.This prospective observational was conducted two large tertiary medical center. determined deteriorate upon...

The COVID-19 pandemic accelerated the assimilation of telemedicine platforms into medical practice. Nevertheless, research-based evidence in this field is still accumulating. This was a prospective, cross-sectional comparative assessment remote physical examination device used mainly for heart and lung digital auscultation. We analyzed usage patterns, user (physician) subjective appreciation compared it to legacy measures. Eighteen physicians (median age 36 years (IQR 32-45): two interns,...

Abstract Background COPD exacerbations have negative impact on patients’ survival. Several risk factors for grave outcomes of such been descried. Muscle dysfunction and mass loss were shown to negatively prognosis Low activity the enzyme ALT (Alanine amino-transferase) in blood is a known indicator sarcopenia frailty, however, no previous studies addressed association low amongst patients hospitalized due exacerbation long-term Methods This historic prospective cohort study acute...

Background: Frailty and sarcopenia are associated with frequent hospitalizations poor clinical outcomes in geriatric patients. Ascertaining this association for younger patients hospitalized internal medicine departments could help better prognosticate the realm of medicine. Methods: During a 1-year prospective study an department, we evaluated upon admission frailty. We used FRAIL questionnaire, blood alanine-amino transferase (ALT) activity, mid-arm muscle circumference (MAMC)...