An easy strategy to obtain nanohydrogels within the halloysite nanotube (HNTs) lumen was investigated. Inorganic reverse micelles based on HNTs and hexadecyltrimethylammonium bromides were dispersed in chloroform, hydrophilic cavity used as a nanoreactor confine gel formation alginate cross-linked by calcium ions. Spectroscopy electron microscopy experiments proved confinement of polymer into HNT calcium-mediated networks. Biological tests biocompatibility hybrid hydrogel. The nanogel...

Hollow halloysite nanotubes have been used as nanocontainers for loading and the triggered release of calcium hydroxide paper preservation. A strategy placing end-stoppers into tubular nanocontainer is proposed sustained from cavity reported. The incorporation Ca(OH)2 nanotube lumen, demonstrated using transmission electron microscopy (TEM) imaging Energy Dispersive X-ray (EDX) mapping, retards carbonatation, delaying reaction with CO2 gas. This effect can be further controlled by...

An impedimetric aptasensor for ochratoxin A (OTA) detection has been developed on the base of a gold electrode covered with new modifier consisting electropolymerized Neutral Red and mixture Au nanoparticles suspended in dendrimeric polymer Botlorn H30®. Thiolated aptamer specific to OTA was covalently attached via Au-S bonding. The interaction induced conformational switch from linear guanine quadruplex form followed by consolidation surface layer an increase charge transfer resistance....

Complexation of biopolymers with halloysite nanotubes (HNTs) can greatly affect their applicability as materials building blocks. Here we have performed a systematic investigation fabrication complexes nucleotides and genomic DNA. The binding DNA various nucleotide species (polyAU, UMP Na2, ADP Na3, dATP Na, AMP, uridine, ATP Mg) by was tested using UV-spectroscopy. study revealed that different to the nanoclay varied but low both in presence absence MgCl2, while MgCl2 facilitated...

We report the first synthesis of zwitterionic thiacalixarenes featuring imidazolium and sulfonate groups on upper rim alkyl (butyl or octyl) fragments lower platform. Despite their amphiphilic structure, these macrocycles exhibit limited water solubility. However, dynamic light scattering detected formation associates for derivatives with octyl moieties at a concentration 0.1 mM. To develop stable materials aqueous environments to investigate functionality sulfonate-imidazolium along...

Abstract An electrochemical aptasensor for ochratoxin A (OTA) detection has been developed on the base of a gold electrode covered with electropolymerized neutral red and silver nanoparticles obtained by chemical reduction macrocyclic ligands bearing catechol fragments. Thiolated aptamers against OTA were covalently attached to via AgS bonding. The interaction induced conformational switch aptamer, which caused increase charge transfer resistance measured EIS in presence ferricyanide ions....

Serratia marcescens is an emerging opportunistic pathogen responsible for many hospital-acquired infections including catheter-associated bacteremia and urinary tract respiratory infections. Biofilm formation one of the mechanisms employed by S. to increase its virulence pathogenicity. Here, we have investigated main steps biofilm SR 41-8000. It was found that growth stimulated nutrient-rich environment. The time-course experiments showed cells adhere surface catheter start produce...

The main goal of this study was creating multifunctional nanoparticles based on rare-earth doped LaF 3 nanocrystals, which can be used as fluorescence thermal sensors operating over the 80–320 K temperature range including physiological (10–50°C). Pr 3+ :LaF (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:msub><mml:mrow><mml:mi>C</mml:mi></mml:mrow><mml:mrow><mml:mi mathvariant="normal">P</mml:mi><mml:mi...

The opportunistic pathogen Serratia marcescens can cause urinary tract infections, respiratory meningitis, and sepsis in immunocompromised individuals. These infections are challenging to treat due the intrinsic resistance of S. an extensive array antibiotics.

Amyloid fibroproliferation leads to organ damage and is associated with a number of neurodegenerative diseases affecting populations worldwide. There are several ways protect against fibril formation, including inhibition. A variety organic compounds based on molecular recognition amino acids within the protein have been proposed for design such inhibitors. However, role macrocyclic compounds, i.e., thiacalix[4]arenes, in inhibiting fibrillation still almost unknown. In present work, use...

Many ribonucleases (RNases) are considered as promising tools for antitumor therapy because of their selective cytotoxicity toward cancer cells. Binase, the RNase from Bacillus pumilus, triggers apoptotic response in cells expressing RAS oncogene which is mutated a large percentage prevalent and deadly malignancies including colorectal cancer. The specific effect binase RAS-transformed due to its direct binding protein inhibition downstream signaling. However, delivery proteins intestine...

Deep eutectic solvents have obtained growing interest in analytical chemistry due to opportunities related the green paradigm, i.e., substitution of organic solvents, application non-toxic ingredients and minimal quantities wastes formed their synthesis usage. In this work, advantages deep were shown development electrochemical sensor for epinephrine determination. Polythionine molecularly imprinted with (PTNMIP) was electrodeposited from natural solvent (NADES) consisted citric acid,...

A series of cobalt (Co) and its oxides based nanoparticles were synthesized by using hyperbranched polyester polyol Boltorn H20 as a platform sodium borohydride reducing agent. UV, FT-IR, XRD, NTA, TEM methods employed to obtain physicochemical characteristics the products. The average diameter Co was approximately<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mn fontstyle="italic">8.2</mml:mn><mml:mo>±</mml:mo><mml:mn fontstyle="italic">3.4</mml:mn></mml:math> nm....

Abstract Electrochemical sensor has been proposed on the base of glassy carbon electrode (GCE) modified with black (CB) and pillar[5]arene (P[5]A). The characteristics peak currents were found to be sensitive incubation in organic acid DNA solution. detection n×(10 −8 –10 −5 ) M down (1–5)×10 −18 g was attributed effect analytes aggregation relative stability oxidized reduced forms P[5]A. No signal interference alkali alkali‐earth metal ions found. electrochemical tested specific...

A highly sensitive electrochemical DNA sensor for detection of the chemotherapeutic drug idarubicin mediated by Methylene blue (MB) has been developed. from fish sperm immobilized at electropolymerized layers Azure B. The incorporation MB into substantially increased sensitivity. concentration range determination cyclic voltammetry was 1 fM to 0.1 nM, with a limit (LOD) 0.3 fM. Electrochemical impedance spectroscopy (EIS) in presence redox probe ([Fe(CN)6]3−/4−) allowed widening linear 100...

Bacillus subtilis is traditionally classified as a PGPR that colonizes plant roots through biofilm formation. The current study focused on investigating the influence of various factors bacilli In course study, levels formation by model strain B. WT 168 and its basis created regulatory mutants, well strains with deleted extracellular proteases under conditions changes in temperature, pH, salt oxidative stress presence divalent metals ions. forms halotolerant stress-resistant biofilms at...

Abstract Novel electrochemical DNA‐sensor based on glassy carbon electrode (GCE) modified with Ag nanoparticles, Neutral red covalently attached to its surface and native DNA adsorbed modifier coating was developed for the estimation of damage example model system Fenton reagent. As shown, oxidation process resulted in synchronous increase electron transfer resistance capacitance measured by impedance spectroscopy (EIS). The contribution each sensor component signal specified sensitivity...

Employing induced asymmetric synthesis, new decasubstituted pillar[5]arenes containing (<italic>R</italic>)-(+)- or (<italic>S</italic>)-(−)-1-phenylethane-1-acetamide fragments have been obtained and characterized.

Functional polydiacetylene vesicles based on thiacalix[4]arene–10,12-pentacosadiynoic acid conjugates showed selective colorimetric response toward lanthanide ions.

For the first time, stable pillar[5]arene/Ag + nanoparticles, consisting of water-soluble pillar[5]arene containing γ-sulfobetaine fragments and Ag ions without Ag–Ag bonds, were synthesized characterized. The (ratio 1:10) nanoparticles obtained cubic with a rib length 100 nm are less cytotoxic than ions. survival A549 model cells in presence (1:10) at concentration 30 40 μM was 76% 55%, while absence pillar[5]arene, cell for free same 30% 10%, respectively. results can be used to create new...

The Pr 3+ :LaF 3 (C = 3, 7, 12, 20, 30%) nanoparticles were characterized by means of high-resolution transmission electron microscopy, X-ray diffraction, optical spectroscopy, energy dispersive dynamic light scattering, and MTT assay. It was revealed that the average diameter all NPs is around 14–18 nm. hydrodynamic radius 7%) strongly depends on medium. radii in water, DMEM, RPMI-1640 biological mediums 18 ± 5, 41 6, 186 8 nm, respectively. nontoxic at micromolar concentrations toward...

Abstract Glassy carbon electrode (GCE) was modified by new polymeric materials obtained from oligolactides cross‐linking with tetracarboxylated thiacalix[4]arene in cone, partial cone and 1,3‐alternate configurations then silver deposited potential cycling the pores of polymer film. The showed highly sensitive selective signal toward tryptophan which irreversibly oxidized on coating due to Ag + assisted accumulation surface layer. role macrocycle configuration conditions for nanodendrites...