A5086342845- Heavy Metal Exposure and Toxicity
- Trace Elements in Health
- Stress Responses and Cortisol
- Lymphoma Diagnosis and Treatment
- Tryptophan and brain disorders
- Occupational Health and Performance
- Injury Epidemiology and Prevention
- COVID-19 and healthcare impacts
- Child Abuse and Trauma
- Air Quality and Health Impacts
- Liver Disease Diagnosis and Treatment
- Child and Adolescent Psychosocial and Emotional Development
- Public Health and Environmental Issues
- Health, Environment, Cognitive Aging
- COVID-19 Clinical Research Studies
- Radioactivity and Radon Measurements
- Hepatitis B Virus Studies
- Electrochemical Analysis and Applications
- COVID-19 diagnosis using AI
- Hepatitis C virus research
- Effects and risks of endocrine disrupting chemicals
- Neuroendocrine regulation and behavior
- Erythropoietin and Anemia Treatment
- Medieval and Early Modern Iberia
- Tracheal and airway disorders
Icahn School of Medicine at Mount Sinai
2020-2024
Williams College
2023-2024
University of North Carolina at Chapel Hill
2023-2024
Rider University
2022
Institut d'Assistència Sanitària
2014
Abstract Timely and effective clinical decision-making for COVID-19 requires rapid identification of risk factors disease outcomes. Our objective was to identify characteristics available immediately upon first evaluation related mortality. We conducted a retrospective study 8770 laboratory-confirmed cases SARS-CoV-2 from network 53 facilities in New-York City. analysed 3 classes variables; demographic, clinical, comorbid factors, two-tiered analysis that included traditional regression...
Early-life environmental exposures during critical windows (CWs) of development can impact life course health. Exposure to neuroactive metals such as manganese (Mn) prenatal and early postnatal CWs may disrupt typical brain development, leading persistent behavioral changes. Males females be differentially vulnerable Mn, presenting distinctive Mn exposure.
Abstract Though considerable work supports the Dimensional Model of Adversity and Psychopathology, prior research has not tested whether dimensions—threat (e.g., abuse) deprivation neglect)—are uniquely related to salivary trait indicators hypothalamic pituitary adrenal (HPA) axis activity. We examined unique interactive effects threat on latent cortisol (LTC)—and these were modified by co‐occurring adversities. Emerging adults ( n = 90; M age 19.36 years; 99.88% cisgender women) provided...
Abstract Timely and effective clinical decision-making for COVID-19 requires rapid identification of risk factors disease outcomes. Our objective was to identify characteristics available immediately upon first evaluation related mortality. We conducted a retrospective study 8770 laboratory-confirmed cases SARS-CoV-2 from network 53 facilities in New-York City. analysed 3 classes variables; demographic, clinical, comorbid factors, two-tiered analysis that included traditional regression...
In the aftermath of World Trade Center (WTC) attack on 11 September 2001, rescue and recovery workers faced hazardous conditions toxic agents. Prior research linked these exposures to adverse health effects, but mainly examined individual factors, overlooking complex mixture effects.
Hispanic and White undergraduates (N = 238) read an online scenario depicting a defendant on trial; documentation status (undocumented, natural-born citizen) background (more sympathetic, less sympathetic) were varied. participants saw the as generally more likely to commit crime than participants. also undocumented most be guilty, while least guilty. These results suggest that defendant-juror similarity has impact juror decisions, even when is undocumented, finding important for those...
Abstract In the aftermath of World Trade Center (WTC) attack, rescue and recovery workers faced hazardous conditions toxic agents. Prior research linked these exposures to adverse health effects, but mainly examined individual factors, overlooking complex mixture effects. This study applies an exposomic approach encompassing totality responders' experience, defined as WTC exposome. We analyzed data from 34,096 members Health Program General Responder, including mental physical health,...
Background: The brain white matter (WM) connects gray regions into functional networks and is critical for human cognition behavior. Early-life metal exposure can disrupt WM maturation lead to long-lasting changes in neuronal circuitry. Despite a growing literature suggesting associations between environmental levels of exposures persistent neurodevelopmental effects, the underlying mechanisms these are poorly understood. Furthermore, influence sex on understudied. goal present study was...
Background/Aim: Developmental neurotoxicity of fluoride has been demonstrated in animal studies. Additionally, exposure during prenatal development, infancy, middle-to-late childhood and adolescence associated with poorer neurodevelopmental outcomes among children Mexico and/or Canada. However, potential impacts chronic low-level early on brain structure neurodevelopment remain relatively unexamined. We conducted the first United States (US) study to examine associations urinary levels...
Background: Manganese (Mn) is an essential nutrient. Homeostatic levels are critical to healthy human development, yet high of exposure can be neurotoxic and result in adverse effects. Given that optimal brain development requires complex maturational processes occur the right order time, both timing intensity Mn matter. Previous research has found windows susceptibility sex-specific associations between unfavorable behavioral outcomes; however, few studies have explored neural mechanisms...
Introduction and Aim: Internalizing disorders, such as anxiety depression, affect 10 – 20% of children increase the risk for later-life psychopathology. The neural circuitry subserving internalizing phenotypes begins developing in utero is vulnerable to early-life environmental exposures. Although exposure metals can adversely impact children's neurodevelopment have lifelong impacts on mental health, little known about critical windows metal exposures adolescent disorders. In this study, we...
Background and Aim. Early-life metal mixture exposure may increase the risk for anxiety depression in adolescence. The neural circuitry subserving internalizing phenotypes begins developing utero is vulnerable to early-life exposures. Resting state functional magnetic resonance imaging (rs-fMRI) provides a novel tool examine underlying mechanisms of metal-associated neurodevelopmental outcomes. We investigate relationships between connectivity pre-adolescents. Methods. In preliminary...