A5003854736- Growth Hormone and Insulin-like Growth Factors
- Genetic Syndromes and Imprinting
- Neuroendocrine Tumor Research Advances
- Connective tissue disorders research
- Pituitary Gland Disorders and Treatments
- Parathyroid Disorders and Treatments
- Bone fractures and treatments
- Fibroblast Growth Factor Research
- Hypothalamic control of reproductive hormones
- Bone health and treatments
- Ion Transport and Channel Regulation
- Diabetes and associated disorders
- Neuroblastoma Research and Treatments
- Birth, Development, and Health
- Respiratory Support and Mechanisms
- Adrenal Hormones and Disorders
- Contact Dermatitis and Allergies
- Education Practices and Challenges
- Soft tissue tumor case studies
- Bone health and osteoporosis research
- Human Health and Disease
- Diabetes Management and Research
- Drug-Induced Adverse Reactions
- Endometriosis Research and Treatment
- Problem Solving Skills Development
Ankara University
2010-2024
Ministry of Health
2018
Sağlık Bilimleri Üniversitesi
2018
Abnormal uterine bleeding (AUB) is the most common gynecologic complaint in adolescent girls. The aim of this study was to identify diagnostic and management differences between those with/without heavy menstrual bleeding.Retrospective data collected from adolescents aged 10-19 years, diagnosed with AUB. Adolescents known disorders at admission were excluded. All girls classified according degree anemia; group 1 had [hemoglobin (Hb) <10 g/dL] 2 moderate or mild (Hb >10 g/dL). Admission...
This study aims to identify the burnout levels of teachers working in preschool, elementary school and private education institutions review if a significant difference is produced by miscellaneous variables their levels. The has been conducted on total 228 at medium socio-economical level province Ankara. "General Information Form" used gather information themselves while "Maslach Burnout Inventory" developed Maslach Jackson (1981). concluded that field work, financial opportunities,...
Secondary osteoporosis is a condition when the underlying disease or its treatment causes bone mass to decrease and structure deteriorate, increasing risk of fracture. The importance diagnosis during childhood adolescence due long-term negative effects. In this study, our objectives were determine diagnostic findings, efficacy, follow-up characteristics with secondary osteoporosis.
Parathyroid adenoma is less common than in adulthood, but its morbidity higher children. We aimed to evaluate the clinical characteristics of parathyroid and our experience since early disease often asymptomatic late diagnosed.From 2010 2020, all children diagnosed with at institution were reviewed. evaluated clinical, biochemical, radiological aspects follow-up characteristics.Eight subjects (F/M = 6/2) ranged age from 10 17 years. Three symptomatic. The symptoms findings stomachache (n 3),...
Diabetic ketoacidosis (DKA) is a common endocrine emergency in pediatric patients. Early presentation to health facilities, diagnosis, and good management the intensive care unit (PICU) are crucial for better outcomes children with DKA.This was single-center, retrospective cohort study conducted between February 2015 January 2022. Patients DKA were divided into two groups according pandemic status diabetes diagnosis.The enrolled 59 patients, their mean age 11±5 years. Forty (68%) had newly...
Hyperprolactinaemia refers to increased circulating prolactin and is divided into functional pathological hyperprolactinaemia. Prolactinoma the most common cause of severe Prolactinomas are rare in children. Treatment outcomes long-term follow-up data children insufficient. Dopamine agonists first step treatment prolactinomas. There no recommendations supported by a high level evidence regarding dose duration cabergoline treatment.Patients with hyperprolactinaemia were evaluated for...
We aimed to determine the prevalence of early puberty in girls with premature pubarche and analyze time interval between their succeeding thelarche. This study included 60 female children pubarche. retrospectively collected clinical, laboratory, radiological findings from all participants. investigated thelarche cases wherein was followed by The mean age at onset 6.93 ± 0.79 yr old. Among participants, 16.7% were preterm, 20% small for gestational (SGA), 55% overweight or obese. 11.20 7.41...
Primary osteoporosis is a rare and essential problem in childhood that can cause severe skeletal deformities. We aimed to reveal the spectrum of primary assess effectiveness safety bisphosphonates increasing bone mineral density reducing fractures.
Central diabetes insipidus (CDI) is a rare but important disease of varying etiology that poses challenges in diagnosis and follow-up. Identifying diagnostic difficulties patients with CDI will help ensure an optimal approach to their management This study aimed characterize the clinical etiological characteristics pediatric patients.We analyzed admission follow-up data aged 0-18 years who were followed our center between 2010 2019.The included 56 mean age at 7.92 ± 5.11 symptom duration...
Standard short adrenocorticotropic hormone (ACTH) stimulation test (SST) has traditionally been used for assessing adrenal gland fuction by intravenous (iv) application. However the iv form is not readily available in all countries, including Turkey. The aim of this study was to evaluate effectiveness intramuscular (im) SST.Patients underwent im SST with suspected insufficiency (AI) and hyperandrogenism. SSTs were done 250 mcg ACTH (Synacthen Depot ampul, concentration 1 mg/mL). cases...
Konjenital hiperinsülinemik hipoglisemi [congenital hyperinsulinemic hypoglycemia (CHH)], yenidoğan dönemindeki dirençli hipoglisemilerin en sık nedenidir. CHH, histolojisine göre; diffüz, fokal ve atipik olarak ayrılmaktadır. Fokal lezyonun yerini tespit etmek için 18F-fluoro-L-DOPA pozitron emisyon tomografisi/bilgisayarlı tomografi (PET/BT), %100 doğruluğu olan bir yöntemdir. Yenidoğan döneminde ciddi ile başvuran, paternal heterozigot ABCC8 mutasyonu edilerek CHH tanısı alan olguda,...
Costello syndrome (CS) is a rare member of the group neuro-cardio-facio-cutaneous diseases known as RASopathies. CS involves characteristic dysmorphic craniofacial features, cardiac defects, and increased cancer susceptibility, depending on heterozygous activating germline mutations in HRAS. Polyhydramnios high birth weight are most common presentations perinatal neonatal periods; while poor postnatal growth, short stature, failure to thrive significant issues infancy. Possible mechanisms...
What is already known about this topic? •Different mutations in the RET are associated with varying age-dependent penetrance and disease manifestations.The American Thyroid Association (ATA) has classified hereditary MTC into three risk categories ("moderate", "high", "highest") based on type of mutation. •The S891A mutation a rare germline moderate medullary thyroid carcinoma (MTC). use sorafenib other RET-targeting tyrosine kinase inhibitors (TKIs) childhood cancers (DTC MTC) quiet rare....
Abstract Objectives Hypochondroplasia (HCH) is characterized by disproportionate short stature and regarded as a milder form of achondroplasia (ACH), which another skeletal dysplasia, both caused variants in fibroblast growth factor receptor 3 ( FGFR3) gene. HCH diagnosis based on the clinical features survey findings. The most common FGFR3 variant affects codon 540, leading to substitution asparagine with lysine about 70% patients. Case presentation Herein, we described radiographical...