A5089847016- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Respiratory and Cough-Related Research
- Inhalation and Respiratory Drug Delivery
- Lichen and fungal ecology
- Pediatric health and respiratory diseases
- Botany and Plant Ecology Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Indoor Air Quality and Microbial Exposure
- Pharmacological Effects and Assays
- Mast cells and histamine
- Dermatology and Skin Diseases
- Food Allergy and Anaphylaxis Research
- Agriculture, Plant Science, Crop Management
- Systemic Sclerosis and Related Diseases
- Drug-Induced Adverse Reactions
- Urticaria and Related Conditions
- Gastroesophageal reflux and treatments
- Cardiovascular Effects of Exercise
- Pneumonia and Respiratory Infections
- Integrated Water Resources Management
- Oral health in cancer treatment
- Industrial and Mining Safety
- Transportation Systems and Safety
- Immune Cell Function and Interaction
Medical University of Białystok
2011-2021
The physician's global evaluation of treatment effectiveness (GETE) at 16 weeks has been shown to be the most effective assessment response omalizumab (XOLAIR®). This randomized, open-label, parallel-group study evaluated persistency responder classification in patients receiving added optimized asthma therapy (OAT).Patients (12-75 years, n = 400) with severe allergic asthma, uncontrolled despite Global Initiative for Asthma 2004 Step 4 therapy, received OAT and (n 272) or 128) 32 weeks....
Background:Long-term oral corticosteroid (OCS) therapy and related adverse events are associated with a significant burden on patients healthcare resources.Methods:This subgroup analysis of randomized, open-label, parallel-group study evaluated the OCS-sparing effect omalizumab (OMA) added to optimized asthma (OAT), compared OAT alone. Patients (12–75 years) severe allergic asthma, uncontrolled despite GINA 2004 Step 4 therapy, received OMA or for 32 weeks. The change from baseline in OCS...
Podstawowym celem tego dokumentu jest opracowanie spójnych wytycznych dotyczących wskazań, przeciwwskazań, metodyki i zasad interpretacji testu 6-minutowego chodu (6MWT, 6 min walk test) w ramach codziennej praktyki szpitalnej ambulatoryjnej [...]
Abstract Objective The leukotrienes are a family of arachidonic acid–derived lipid mediators with proinflammatory and profibrotic properties. aim this study was to analyze the role leukotriene B 4 (LTB ) LTE in pathogenesis scleroderma lung disease (SLD). Methods Nineteen systemic sclerosis (SSc) patients SLD, 11 SSc without 10 healthy controls were studied. Bronchoalveolar lavage (BAL) fluid obtained during routine bronchoscopy right middle lobe all subjects. Levels LTB measured using...
Recognition of individual allergens by IgE is crucial for triggering symptoms in allergic rhinitis (AR) or asthmatic (AA) patients. House dust mite (HDM) allergy frequent around the world, sensitization profile to HDM varies HDM-allergic patients (APs). The aim this study was evaluate pattern three major Dermatophagoides pteronyssinus (Dp) among from North Eastern Poland suffering HDM-AR and/or AA. performed on 323 AA and 106 controls (CG) including 30 healthy non-atopic subjects, 32 AR not...
Background: The presence of immunoglobulin E (IgE), which cross-reacts with allergen components, such as profilins, polcalcins, and cross-reacting carbohydrate determinants (CCD), creates a problem when selecting patients for immunotherapy by using conventional methods. aim this study was to evaluate the prevalence sensitization CCDs in seasonal pollen allergic rhinitis. Methods: performed on group 112 rhinitis, ages 14 55 years, at least one (IgE > 0.7 kUA/L). IgE recombinant (r) Bet v...
Changes in fractional exhaled nitric oxide (FeNO) occurring after bronchial allergen challenges (BAC) are still not understood, neither any possible associations between FeNO and forced expiratory volume 1 sec (FEV(1)). The aim of the study was to compare fluctuations FEV(1), which occur within 72 h BAC children sensitive grass pollen.Seventy-four were divided into two groups based on their medical histories results skin prick tests with 10 common allergens. Individuals whom test yielded a...
A high strength of beclomethasone/formoterol fumarate (BDP/FF) in a pressurised metered dose inhaler (pMDI), which contains extrafine BDP (200 μg/actuation) and FF (6 has been developed to treat those asthmatics who are not adequately controlled on previous treatments. 12-week, randomized, double-blind, parallel group study was performed compare the efficacy safety pMDI BDP/FF 200/6 (two actuations bid) with 100 μg (four actuation population 376 randomized adult inhaled corticosteroids (ICS)...
The aim of the present study was to compare mugwort pollen season in 2018 Bialystok, Bydgoszcz, Cracow, Drawsko-Pomorskie, Lublin, Olsztyn, Opole, Sosnowiec, Szczecin, Warsaw, Wroclaw, and Zielona Gora. Pollen concentration measurements were made by volumetric method using Burkard or Lanzoni samplers. considered as period during which 98% total annual count occurred. Seasonal Index (SPI) calculated sum average daily concentrations throughout determined for individual cities. started earliest...
This paper presents the course of goosefoot pollination in selected cities Poland 2018. The measurements were performed Bialystok, Bydgoszcz, Cracow, Drawsko Pomorskie, Lublin, Olsztyn, Opole, Piotrkow Trybunalski, Sosnowiec, Szczecin, Warsaw, Wroclaw, and Zielona Gora. Volumetric method with use Spore Trap (Burkard, Lanzoni) was implemented. In studied 2018, pollen season started third decade May ended September. Goosefoot stayed air for more than 100 days – 142 Sosnowiec 109 Bialystok....
There are many potential factors that can modulate bronchial reactivity, including exposure to allergens, viral infections, and medications. The aim of this study was analyze the effect grass pollination intensity on reactivity in seasonal allergic rhinitis (SAR) patients subjected subcutaneous allergenic immunotherapy (SCIT).This study, performed between 2005 2008, included 41 with confirmed sensitivity pollens predominating symptoms SAR, randomly assigned desensitization by pre-seasonal or...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Mincewicz G, Siergiejko Piepiorka M, Świdnicka-Siergiejko A, Z, Krzykowski G. Functional assessment of the right ventricle in patients with bronchial asthma various severity. Advances Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2021;38(1):52-56. doi:10.5114/ada.2021.104278. APA Mincewicz, G., Siergiejko, Piepiorka, M., Świdnicka-Siergiejko, A., Z., & Krzykowski, (2021). Alergologii, 38(1),...
Objective. The aim of this study was to compare the usefulness mannitol provocation test that classical histamine challenge in children with PC20FEV1 lower than 4 mg/ml. Methods. Twenty-two adolescent patients (mean age 15.4 ± 4.1 years) established asthma (PC20FEV1 below mg/ml) were included study. Bronchial performed 1–2 days after histamine. Results. fraction positive results markedly when compared (72.7% vs. 100%, p = .015). discontinued one case due severe coughing inhalation 315 mg...
The study compares the yew and juniper pollen seasons in Bialystok, Bydgoszcz, Cracow, Katowice, Piotrkow Trybunalski, Opole, Szczecin, Zielona Gora, Warsaw, Wroclaw Lublin 2019. investigations were carried out using volumetric method (Hirst type sampler). Seasonal Pollen Index (SPI) was estimated as sum of daily average concentrations given season. pollination is mainly observed February March, while March April. Due to morphological similarity grains both taxa, are considered together....
Concentration of nitric oxide in exhaled air (FeNO) was revealed to decrease as a result immunotherapy. However, individuals who are exposed environmental allergens characterized by elevated values FeNO. The aim this study analyze the effects subcutaneous immunotherapy (SCIT) on dynamics FeNO determined during consecutive pollination seasons.This study, performed between 2005 and 2008, included 41 patients with confirmed sensitivity grass pollens predominating symptoms seasonal allergic...
The study compares the course of spore season Alternaria in Bialystok, Cracow, Olsztyn, Piotrkow Trybunalski, Sosnowiec, Szczecin, Warsaw, and Wroclaw 2020. investigations were conducted using volumetric method. was defined as period which 90% annual total catch occurred. started first Bialystok on May 19 lasted June 28 Wroclaw. highest airborne concentration 1052 spores/m3 noted July 30. sum spores (SPI) observed Warsaw (19 390 spores) lowest (5769 spores). Most days, threshold inducing...