A5068831938- Nonmelanoma Skin Cancer Studies
- Cutaneous Melanoma Detection and Management
- Cutaneous lymphoproliferative disorders research
- Dermatologic Treatments and Research
- Laser Applications in Dentistry and Medicine
- Surgical Sutures and Adhesives
- Nail Diseases and Treatments
- Genetic and rare skin diseases.
- Skin Protection and Aging
- Optical Coherence Tomography Applications
- Medicine and Dermatology Studies History
- Wound Healing and Treatments
- Digital Imaging in Medicine
- Autoimmune Bullous Skin Diseases
- Photodynamic Therapy Research Studies
- Plant Pathogens and Fungal Diseases
- Cell Image Analysis Techniques
- Psychotherapy Techniques and Applications
- AI in cancer detection
- Hidradenitis Suppurativa and Treatments
- Complementary and Alternative Medicine Studies
- Infectious Diseases and Mycology
- Dermatological diseases and infestations
- Dermatology and Skin Diseases
- Cancer and Skin Lesions
SUNY Downstate Health Sciences University
2015-2024
VA NY Harbor Healthcare System
2015-2024
State University of New York
2011-2023
New York University
2023
Pennsylvania State University
2023
Baylor University Medical Center
2021
Dermatology, Laser & Vein Specialists of the Carolinas
2021
Long Island Skin Cancer and Dermatologic Surgery
2011-2021
Dermatology Specialists
2021
University of Arizona
2021
Background and Objective Low level light therapy has garnered significant interest within the past decade. The exact molecular mechanisms of how red near infrared result in physiologic modulation are not fully understood. Heme moieties copper cells photoreceptors that induce mitochondrial respiratory chain component cytochrome C oxidase, resulting a cascade linked to cytoprotection cellular metabolism. centers oxidase have broad absorption range peaks around 830 nm. Several vitro vivo animal...
Previous American Telemedicine Association (ATA) Teledermatology Practice Guidelines were issued in 2007. This updated version reflects new knowledge the field, technologies, and need to incorporate teledermatology practice a variety of settings, including hospitals, urgent care centers, Federally Qualified Health Centers, school-based clinics, public health facilities, patient homes.
Abstract Background Machine learning algorithms achieve expert‐level accuracy in skin lesion classification based on clinical images. However, it is not yet shown whether these could have high when embedded a smartphone app, where image quality lower and there variability taking scenarios by users. In the past, applications were criticized due to lack of accuracy. Objective this study, we evaluate newest version application ( SA ) for risk assessment lesions. Methods This uses machine...
About 3 million surgical pigmented skin lesion biopsies are performed each year in the USA alone to diagnose fewer than 200 000 new cases of invasive melanoma and situ using current standard care that includes visual assessment histopathology. A recently described noninvasive adhesive patch-based gene expression rule-out test [pigmented assay (PLA)] may be helpful identifying high-risk lesions aid with biopsy decisions. The main objective this utility study was determine real-world clinical...
<b><i>Background:</i></b> Mobile health (mHealth) consumer applications (apps) have been integrated with deep learning for skin cancer risk assessments. However, prospective validation of these apps is lacking. <b><i>Objectives:</i></b> To identify the diagnostic accuracy an app a convolutional neural network detection premalignant and malignant lesions. <b><i>Methods:</i></b> We performed multicenter study CE-marked...
Optical coherence tomography (OCT) is a noninvasive imaging technique that uses low-power infrared laser to image up 2 mm beneath the skin's surface.To test feasibility and diagnostic value of using in vivo OCT define excision margins before Mohs micrographic surgery (MMS) basal cell carcinoma (BCC).Patients with biopsy confirmed BCC undergoing MMS were recruited (n = 52). Excision defined by experienced dermatologists compared those OCT-assessed borders validated histologic...
Optical coherence tomography (OCT) has potential as a modality for in vivo imaging of non-melanoma skin cancer (NMSC). By allowing identification sub-surface margins NMSC lesions, the use OCT could improve rate complete excision and reduce average number stages during Mohs micrographic surgery (MMS). The objective this study was to delineate apparent lesions prior their by MMS. Lesions were scanned with reference physical marker on skin, then identified from images marked skin. Photographs...
Bleeding is a common occurrence during any dermatologic surgery that disrupts blood vessels. The complications of excess bleeding can include delayed wound healing, hematoma formation, infection, dehiscence, and necrosis. In part one this review, we discussed the pre-operative, intra-operative, post-operative management patients undergoing surgery. Part two, discuss traditional new topical hemostatic agents used to achieve hemostasis in dermatological procedures We will evaluate caustic...
Red light is part of the visible spectrum. The effects light-emitting diode (LED)-generated red on human skin are not well-characterized.To study effect LED-generated low-level therapy (LLLT) fibroblast proliferation and viability in vitro.Irradiation normal fibroblasts using LED panels was performed vitro, modulation quantified trypan blue dye exclusion assay.Statistically significant decreases cell were noted at following fluences (time): 160 J/cm2 (30 minutes, 34 seconds), 320 (61 07...
Actinic keratoses (AKs) are generally accepted as common precursor lesions to invasive squamous cell carcinoma. Photodynamic therapy (PDT) is a common, in-office, field modality used in the treatment of AKs. Clinical and laboratory observations have demonstrated that temperature modulation can affect PDT efficacy.To demonstrate thermal increases apoptotic death, investigate mechanistic role reactive oxygen species (ROS) free radicals an vitro human skin fibroblast model.This study was...
Scars, including hypertrophic and keloidal-type scars, may occur after burns, trauma, or surgery. Despite several treatment options available for few effective, noninvasive modalities exist. Recently, a small clinical studies revealed the possible benefit of red infrared (IR) low-level light therapy (LLLT) in scar treatment. One important features scars is proliferation dermal fibroblasts, but vitro data regarding effects light-emitting diode (LED)-generated IR on human skin fibroblasts...
A recently described noninvasive gene expression test (the pigmented lesion assay [PLA]) with adhesive patch-based sampling has the potential to rule out melanoma and need for surgical biopsy of lesions suggestive a negative predictive value 99% compared 83% histopathologic standard care. The cost implications using this molecular vs visual assessment followed by (VAH) have not been evaluated.To determine savings PLA use VAH pathway.This health economic analysis performed from US payer...
The Pigmented Lesion Assay (PLA, sensitivity 91-95%, specificity 69-91%, negative predictive value ?99%) is a commercially available, non-invasive gene expression test that helps dermatologists guide pigmented lesion management decisions and rule out melanoma. Earlier studies have demonstrated high clinical utility no missed melanomas in 3-6-month follow-up period. We undertook the current investigations to provide 12-month data on PLA(-) tests, further confirm utility. A chart review of 734...