<h3>Background</h3> In August 2012, new national guidance (National Institute of Health and Care Excellence (NICE) CG149) for management early onset sepsis (EOS) was introduced in the UK. The outlined a consistent approach septic screens newborn infants based on risk factors, suggested biochemical clinical parameters to guide management. particular, it advised second C-reactive protein level (CRP) 18–24 h into treatment help determine length antibiotic course, need lumbar puncture (LP),...

Dengue, a mosquito-borne disease caused by flavivirus, is recognized in over 120 countries with 3.6 billion people living areas at risk. Neurological manifestations are infrequently reported as clinical consequences of dengue infection. Though severe may be associated meningoencephalitis, meningitis rare initial presentation otherwise uncomplicated fever. We report two adult patients who presented fever, headache, and nuchal rigidity without the typical symptoms Cerebrospinal fluid (CSF)...

A haemodynamically significant patent ductus arteriosus (hsPDA) contributes significantly to mortality and morbidity in infants born earlier than 28 weeks’ gestation. Intravenous ibuprofen is the only licensed medication for medical management of (PDA) UK. It has its own side effects. There emerging evidence suggest that paracetamol may be a safer substitute ibuprofen. We carried out national telephone survey ascertain majority response on off-label use explore areas possible research...

Objective To compare the characteristics and short-term outcomes in extremely preterm infants, who developed necrotizing enterocolitis (NEC) following a packed red blood cell transfusion (pRBC) within 48 h (TANEC), with those NEC beyond (non-TANEC).Setting A single-center retrospective cohort study Tertiary neonatal intensive care unit UK over 5-year periodPatients methods Extremely premature infants (23–27 weeks gestation) were selected. TANEC non-TANEC incidence calculated from confirmed...

Implementing the smart grid will require intelligent interaction between power generating and consuming devices, which is achieved by installing devices capable of processing data communicating it to various parts in grid. The role embedded processors be achieve high performance given real time situations. carry out tasks similar security encryption, signal processing, flow calculation etc. are essential for analysis proper transmission. Depending on where processor hierarchy, application...

Many advancements have been made in the area of health sciences and analytics since advent Internet Things (IoT) highly accurate predictive models using Machine Learning (ML). The problem migraine, a debilitating headache which usually causes chronic neurological disorders for patients, is one such where both these technologies can prove to be useful help us gain insights into prevention problem. Prevention migraine only come from ubiquitous autonomous observation correlation triggers...

The central outer tracker (COT) is a big cylindrical drift chamber that provides charged particle tracking for the collider detector at Fermilab experiment. To protect COT, large stored energy in high-voltage (HV) system needs to be removed quickly when problem sensed. For HV switch, special-order silicon-controlled-rectifier was chosen over more readily available integrated gate bipolar transistors because of layout and reliability questions. considerations concerning prototype performance,...

<h3>Aim</h3> To emphasis the importance of history taking in diagnosing maturity onset diabetes young (MODY) <h3>Methods/Results</h3> MODY accounts for around 2% paediatric diabetic cases. Mutation hepatocyte nuclear factor 1-beta (HNF1-β) gene is rare (accounting approximately 6% diagnoses UK) and associated with RCAD (renal cysts diabetes) syndrome. Owing to common clinical features both type 1 2 diabetes, diagnosis proves be a challenge. A 7 year old girl presented polydipsia, polyuria...

Southwest Missouri has a karst region and several sinkhole collapses had been reported in the past decade. The objective of this study was to create probability map using logistic regression coupled with GIS identify areas susceptible collapse for efficient land management decision making urban planners. Logistic model is one most common models used predict latent binary qualitative outcome as function number explanatory variables. In study, establish functional relationship between...

<h3>Background</h3> The UK on 01 September 2015 became the first country to introduce Meningococcal B (Bexsero) vaccine into national infant immunisation programme. Bexsero is recommended for all infants as part of their routine vaccinations at ages 2, 4 and 12 months alongside other regular vaccines. highly immunogenic estimated protect against 73%–88% MenB strains causing invasive meningeal disease (IMD) in England Wales1. <h3>Objective</h3> We retrospectively evaluated tolerability...

The large cylindrical drift chamber in the CDF detector at Fermilab Tevatron operates with high stored electrical energy. has more than 63,000 sense and potential wires voltage a jet cell configuration 8 superlayers. Each wire about 1 nf added capacitance to ground provide filtering, signal termination, cross-talk reduction. Since is provided by 200 supplies, numbers of must be daisy chained together resultant energy 2 joules on daisy-chains outermost wires. When starts discharge ground, it...

<h3>Background</h3> Hypertension in the neonatal period is uncommon with studies reporting an incidence of 0.2–3%. There little data on clinical course and outcome these infants. <h3>Objectives</h3> To evaluate hypertension <h3>Methods</h3> A retrospective observational study newborn infants admitted to NICU over a 10 year (January 2011 December 2020). was defined as systolic BP &gt;95th centile for gestation age at least 3 consecutive readings measured using indwelling arterial line or...