Abstract Background: Medical students’ psychological response to societal lockdown during the covid-19 pandemic has not been studied much. Our aim was assess levels of anxiety and depression among medical students initial stages in Nepal relate their distress psychosocial other relevant situational variables. Materials Methods: A cross-sectional study with an online questionnaire conducted at different colleges Nepal. Hospital Anxiety Depression Scale (HADS) detected manifestations...

Background Medical students’ psychological response to societal lockdown during the COVID-19 pandemic has not been studied much.
 Objective To assess levels of anxiety and depression among medical students initial stages in Nepal relate their distress relevant variables.
 Method A cross-sectional study with online questionnaire was conducted at different colleges Nepal. Hospital Anxiety Depression Scale (HADS) detected ‘anxiety’ ‘depression’. The covariates were explored by...

Iron deficiency with or without anemia is a common comorbidity co-existing heart failure patients and an independent risk factor for exacerbation worse prognosis. A growing number of randomized clinical trials meta-analysis evaluated the efficacy safety intravenous iron use in patients. However, findings from them are inconsistent often conflicting. This was performed based on PRISMA (Preferred Reporting Items Systematic Reviews Meta-Analyses) guidelines after registering PROSPERO...

and importance: Hypothyroidism is an endocrine disorder with multiorgan involvement various complications. One of the significant but less often seen complications pericardial effusion. Since it can progress to life-threatening conditions like cardiac tamponade hemodynamic instability, early diagnosis, management effusion in hypothyroidism a must.We present case 35-year-old male who presented bilateral lower limb swelling, facial puffiness, cold intolerance, fatigue, hoarseness voice for one...

Subcutaneous ICD (S-ICD) was designed to reduce lead and pocket related complications by creating an extrathoracic defibrillator system without need for venous access. However, there is limited data on the clinical characteristics outcomes of patients undergoing S-ICD implantation in real-world settings.

e24029 Background: Radiation therapy (RT) for malignancy in mediastinal region is associated with radiation-induced heart disease subsequent years, including coronary, valvular, myocardial, pericardial and conduction system disease. Although increased risk of diastolic failure (DHF) has been established, there limited data on the prevalence, trends outcomes acute DHF admissions patients prior RT. Methods: We extracted from National Inpatient Sample (NIS) Database 2016 to 2020. included all...

e24031 Background: Cancer patients and survivors face an elevated risk of coronary artery disease due to shared factors. Risk is further heightened by cancer itself as well its treatment. Acute myocardial infarction (AMI) becoming a leading cause death among this demographic, owing significant advancements in survival recent decades. While racial disparities outcomes resource utilization AMI hospitalizations are well-documented, data on with remain limited. Methods: We extracted from the...

e24027 Background: Patients with multiple myeloma (MM) are at increased risk of cardiovascular events secondary to its complications and adverse effects pharmacotherapy. However, data on in-hospital outcomes MM acute myocardial infarction (AMI) is limited due the clinical scenario being relatively uncommon. Thus, we conducted a retrospective study investigate resource utilization AMI admissions in patients. Methods: We extracted from National Inpatient Sample (NIS) Database 2016 2020....

e24030 Background: Cancer patients are at a higher risk of infective endocarditis (IE) due to immunosuppressed state, indwelling catheters and recurrent infections. Due the clinical scenario being relatively uncommon, there is lack real-world data on prevalence, trends outcomes IE in cancer patients. Methods: We extracted from National Inpatient Sample (NIS) Database 2016 2020. included all admissions ≥18 years old with principal diagnosis without using International Classification Diseases...

e19531 Background: Multiple myeloma (MM) exhibits a disproportionately higher prevalence among African American individuals. Various factors contribute to the disease's progression, severity, and prognosis. This analysis presents real-world data from National Cancer Database (NCDB) 2010 2020. Methods: Cohort of 241,446 MM patients between 2020 were analyzed. Demographic variations, including age, gender, insurance status, educational attainment, median household income, examined....

e15501 Background: Anal cancer comprises about 2.5% of all gastrointestinal malignancies in the USA. The incidence anal is showing an increasing trend, however studies surrounding its prognostic factors and survival limited. aim our study to examine evaluate trends from 2000-2020 using SEER database. Methods: SEER*Stat Version 8.4.3 software was used extract anus, canal anorectal carcinoma cases 17 registries (2000-2020). A total 32315 patients were included study, data with unconfirmed...

9048 Background: Social media platforms have emerged as pivotal tools for communication, outreach, and engagement. This study aims to assess the adoption utilization of social among Accreditation Council Graduate Medical Education (ACGME) accredited Hematology Oncology (HO) fellowship programs, examining correlation between program characteristics presence. Methods: A comprehensive review was conducted all ACGME-accredited HO programs identify their presence on popular platforms, Twitter/X...

e16210 Background: Primary gallbladder cancer is a rare but aggressive with poor outcomes. Our study aims to understand the survival trends of patients (PGC) and analyze prognosis factors based on cases registered in SEER database from 2000 2020. Methods: We usedSEER*Stat Version 8.4.3 software extract primary carcinoma 17 registries (2000-2020). 20,143 were included study. Those unconfirmed histology excluded. analyzed overall mortality cancer-specific (CSM) using Cox proportional hazards...

e14684 Background: Immune checkpoint inhibitors (ICIs) are increasingly used to treat multiple cancers uncovering varieties of immune-related adverse events (irAEs). ICI-related haemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome caused by exaggerated activation macrophages and cytotoxic T cells resulting in fatal hematological toxicity multi-organ damage. Methods: We conducted retrospective analysis reported cases HLH patients treated with using data from the...

Osteogenesis imperfecta (OI) is a group of rare, permanent genetic bone disorders resulting from the mutations in genes encoding type 1 collagen. It usually inherited by an autosomal dominant pattern, but it can sometimes occur sporadically. Among four main types, III most severe which presents with multiple fractures, skeletal deformities, blue sclera, hearing, and dental abnormalities. estimated that only 20,000 cases OI are detected during infancy, diagnosis carries poor prognosis. This...

Introduction: Chronic otitis media is a common entity in our country. Surgical eradication of disease the treatment choice for squamous chronic media. The objective this study was to assess pathology, its extent and associated complications patients who underwent open mastoido-epitympanectomy at tertiary care center (Dhulikhel Hospital) Nepal. Materials methods: Medical records 111 OMET from June 2017 2021 were analyzed retrospectively. Demographic parameters, clinical presentation,...

Mullerian duct anomaly such as uterine didelphys is a rare congenital of female genitourinary tract presenting with dysmenorrhea, hematocolpus, and subfertility in adolescent females. It commonly associated wolffian like renal agenesis. Here we present association psoas abscess agenesis 21-year-old unmarried female.We report case right hip pain, recurrent genital infections dysmenorrhea. Her labs suggested infectious etiology whereas radiological investigation revealed abscess. In addition,...