A5042644144- Autoimmune Neurological Disorders and Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Peripheral Neuropathies and Disorders
- Platelet Disorders and Treatments
- Chronic Lymphocytic Leukemia Research
- Agriculture and Rural Development Research
- CNS Lymphoma Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Animal Diversity and Health Studies
- Blood groups and transfusion
- Pharmacological Effects and Toxicity Studies
- Ruminant Nutrition and Digestive Physiology
- Multiple Myeloma Research and Treatments
- Blood properties and coagulation
- Chronic Myeloid Leukemia Treatments
- Renal Transplantation Outcomes and Treatments
- Prion Diseases and Protein Misfolding
- Colorectal Cancer Treatments and Studies
- Biliary and Gastrointestinal Fistulas
- Inflammatory Myopathies and Dermatomyositis
- Soybean genetics and cultivation
- Trypanosoma species research and implications
- Neuroblastoma Research and Treatments
- Chemotherapy-induced organ toxicity mitigation
- Parasites and Host Interactions
Moffitt Cancer Center
2024-2025
University of South Florida
2025
Mayo Clinic in Arizona
2022-2024
Mayo Clinic
2021-2024
WinnMed
2021-2024
Jacobi Medical Center
2021-2024
Hôpital La Rabta
2024
Tunis El Manar University
2009-2024
Albert Einstein College of Medicine
2023-2024
Montefiore Medical Center
2023-2024
Objective This study was undertaken to describe a novel biomarker of germ cell tumor and associated paraneoplastic neurological syndrome (PNS). Methods Archival sera from patients with tumor–associated PNS were evaluated. We identified common autoantigen in human testicular cancer line (TCam‐2) by Western blot mass spectrometry. Its identity confirmed recombinant‐protein blot, enzyme‐linked immunosorbent assay (ELISA), cell‐based assay. Autoantibody specificity analyzing assorted control...
Objectives To report the expanded neurological presentations and oncological associations of tripartite motif-containing protein 46 (TRIM46)-IgG seropositive patients. Methods Archived sera/cerebrospinal fluid (CSF) were evaluated by tissue-based immunofluorescence assay to identify patients with identical axon initial segment (AIS)-specific staining pattern. Phage immunoprecipitation sequencing (PhIP-Seq) was used putative autoantigen. Results IgG in serum (17) and/or CSF (16) from 25...
<h3>Importance</h3> Immune-mediated rippling muscle disease (iRMD) is a rare myopathy characterized by wavelike contractions (rippling) and percussion- or stretch-induced mounding. A serological biomarker of this lacking. <h3>Objective</h3> To describe novel autoantibody iRMD report associated clinicopathological characteristics. <h3>Design, Setting, Participants</h3> This retrospective cohort study evaluated archived sera from 10 adult patients at tertiary care centers the Mayo Clinic,...
Abstract Neuroblastoma (NB) is an aggressive malignant tumor arising from a primitive neural crest origin. While the significance of location in survival outcomes recognized, it remains inadequately explored. This study provides comprehensive analysis and characteristics pediatric adrenal nonadrenal NBs United States. A retrospective primary NB between 1975 2016 was conducted using Surveillance, Epidemiology, End Results (SEER) database. Univariate multivariate regression analyses were used...
<h3>Background and Objective</h3> Multiple studies highlighting the diagnostic utility of neurofascin-155 (NF155)–immunoglobulin G4 (IgG4) in chronic demyelinating inflammatory polyradiculoneuropathy (CIDP) have been published. However, few comprehensively address long-term outcomes or clinical NF155–immunoglobulin M (IgM) G (IgG) absence NF155-IgG4. We evaluated phenotypic histopathologic specificity differences between these NF155 antibody isotypes IgG subclasses. also compare...
Injury is an important cause of mortality and morbidity. It the second most common death in United Arab Emirates (UAE) for last 15 years, claiming more than 1200 lives annually. Those numbers can be significantly reduced through first aid (FA) education training. The aim this study was to investigate knowledge attitude toward FA UAE.Self-administered questionnaires were distributed nonprobability sampling method 500 residents across UAE, aged at least 30 years. Data collection conducted...
Objective Cochleovestibulopathy is a distinguishable paraneoplastic phenotype. In this study, we evaluate clinical presentation, serological/cancer associations and outcomes of cochleovestibulopathy. Methods Retrospective chart review patients with hearing impairment and/or vestibulopathy who underwent serological evaluations for antibodies between January 2007 February 2021 was performed. Results Twenty-six were identified (men, n=23; median age, 45 years, range: 28–70). Biomarkers detected...
The Intrauterine Contraceptive Device (IUD), a widely used contraceptive since 1965, has demonstrated efficacy but is associated with complications such as bleeding, pain, and rare occurrences of perforation. This case report details an IUD migration into the peritoneal cavity, leading to acute appendicitis.
Diagnostic criteria emphasize the use of sensitive and disease-specific tests to distinguish patients with rapidly progressive dementia (RPD) due Creutzfeldt-Jakob disease (CJD) vs other causes (mimics). These are often performed in specialized centers, results taking days return. There is a need leverage clinical features reporting RPD CJD from those (mimics) early symptomatic course.
Primary cardiac sarcoma, a rare tumor with an aggressive course and imprecise prognosis, constitutes over 95% of all malignant tumors. Given the sparsely available evidence, there is paucity information regarding current knowledge on sarcoma. This study aimed to determine incidence incidence-based rates, patient characteristics, treatment modalities, survival factors sarcoma.A retrospective analysis incidence, mortality rates characteristics sarcoma between 1975 2016 was carried out using...
Three clinico-epidemiological forms of cutaneous leishmaniasis (CL) exist in Tunisia: zoonotic (ZCL; epidemic the centre and south-west); sporadic (SCL; found north); chronic (CCL; originally described from Tataouine, south-east). As few isolates Leishmania Tunisian cases CL have been typed, were collected, using NNN medium, 71 such cases. Most (59) investigated came north country, including 16 Sidi Bourouis, where there was an outbreak SCL early 2001; other 12 natives or south country. The...
The pathophysiology of immune thrombocytopenia (ITP) involves immune-mediated platelet destruction. presence adipose tissue in obese individuals creates an inflammatory environment that could potentially impact the clinical course and outcomes ITP. However relationship between obesity ITP has not been well described. We evaluated 275 patients diagnosed with primary from 2012 to 2022. Patients were categorized into four groups based on their body mass index (BMI) at diagnosis. Female gender...
Studies evaluating Cisplatin-induced nephrotoxicity in minorities are limited. We conducted a retrospective review of adult patients receiving cisplatin from 2019 to 2023 at an inner-city hospital. Renal indices were obtained baseline and after cycles 1, 2, 3 Cisplatin. A total 93 included, 46% male. Median age was 57 years. About 40% Black, 13% White, 42% Hispanic. 54% uninsured. 16% the developed AKI cycle 1 cisplatin, 5% 2%, 17% 3. There no statistically significant correlation between...
Introduction: Caffeine is widely used as a cognitive, physical, and psychomotor booster. Recent studies have suggested worrying trends of overconsumption caffeine, accompanied by higher risk for multiple diseases, including diabetes mellitus type 2. There's general lack research in the middle east regarding caffeine consumption patterns. The aim this study to assess levels among United Arab Emirates (UAE) adult population, well population knowledge attitude its health implications. Methods:...
We propose to study the natural convection flow resulting from interaction of a fire with walls that surround it.Indeed, when occurs in tunnel or tower block, it creates thermal plume causing heating neighbouring walls.This by radiation phenomenon thermosiphon which interacts plume.To this we simulated problem at laboratory where placed rectangular source heated Joule effect entrance an open-ended vertical canal.The visualization laser plan and exploration dynamic fields inside canal enabled...