R. Nagarajan

ORCID: 0000-0002-3937-8735
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About
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Research Areas
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Skin Protection and Aging
  • Genomics, phytochemicals, and oxidative stress
  • Drug Transport and Resistance Mechanisms
  • Phytochemicals and Antioxidant Activities
  • Antioxidant Activity and Oxidative Stress
  • Free Radicals and Antioxidants
  • Rare-earth and actinide compounds
  • Essential Oils and Antimicrobial Activity
  • Cardiac Ischemia and Reperfusion
  • Redox biology and oxidative stress
  • Boron and Carbon Nanomaterials Research
  • Nanoparticle-Based Drug Delivery
  • Cancer therapeutics and mechanisms
  • melanin and skin pigmentation
  • Bee Products Chemical Analysis
  • Sesame and Sesamin Research
  • Carcinogens and Genotoxicity Assessment
  • RNA Interference and Gene Delivery
  • Effects of Radiation Exposure
  • Cell death mechanisms and regulation
  • Metal complexes synthesis and properties
  • Iron-based superconductors research
  • Photodynamic Therapy Research Studies

Annamalai University
2016-2025

Kalasalingam Academy of Research and Education
2024

Shivaji University
2023

Office of the Chief Scientist
2022

Central Institute for Research on Cattle
2021-2022

Narayana Dental College and Hospital
2012-2015

National Cancer Institute
2013-2014

National Institutes of Health
2013-2014

Center for Cancer Research
2013-2014

Narayan Medical College and Hospital
2014

We report here our discovery of bulk superconductivity at rather high ${\mathit{T}}_{\mathit{c}}$ in samples having nominal compositions ${\mathrm{YNi}}_{4}$${\mathrm{BO}}_{0.2}$ (${\mathit{T}}_{\mathit{c}}$\ensuremath{\approxeq}12.5 K) and ${\mathrm{YNi}}_{2}$${\mathrm{B}}_{3}$${\mathrm{O}}_{0.2}$ (${\mathit{T}}_{\mathit{c}}$\ensuremath{\approxeq}13.5 K). While ${\mathrm{YNi}}_{4}$${\mathrm{BC}}_{0.2}$ seems to be a single phase material,...

10.1103/physrevlett.72.274 article EN Physical Review Letters 1994-01-10

Rotenone a widely used pesticide that inhibits mitochondrial complex I has been to investigate the pathobiology of PD both in vitro and vivo . Studies have shown neurotoxicity rotenone may be related its ability generate reactive oxygen species (ROS), leading neuronal apoptosis. The current study was carried out neuroprotective effects hesperidin, citrus fruit flavanol, against rotenone-induced apoptosis human neuroblastoma SK-N-SH cells. We assessed cell death, membrane potential, ROS...

10.1155/2013/102741 article EN cc-by Oxidative Medicine and Cellular Longevity 2013-01-01

Ultraviolet-B radiation (285–320 nm) elicits a number of cellular signaling elements. We investigated the preventive effect linalool, natural monoterpene, against UVB-induced oxidative imbalance, activation mitogen-activated protein kinase (MAPK) and nuclear factor kappa-B (NF-κB) in HDFa cells. observed that linalool treatment (30 μM) prevented acute UVB-irradiation (20 mJ/cm2) mediated loss activities antioxidant enzymes The comet assay results illustrate significantly prevents...

10.1371/journal.pone.0176699 article EN cc-by PLoS ONE 2017-05-03

P-Glycoprotein (P-gp) serves as a therapeutic target for the development of inhibitors to overcome multidrug resistance in cancer cells.

10.1039/c6mb00187d article EN Molecular BioSystems 2016-01-01

Abstract In this study, the effect of caffeic acid ( CA ) on both acute and chronic UVB ‐irradiation–induced inflammation photocarcinogenesis was investigated in S wiss albino mice. Animals were exposed to 180 mJ cm −2 once daily for 10 consecutive days thrice weekly 30 weeks study respectively. exposure showed edema formation, increased lipid peroxidation decreased antioxidant status with activation inflammatory molecules such as TNF ‐ α , IL ‐6, COX ‐2 NF κ B . However, (15 mg per...

10.1111/php.12522 article EN Photochemistry and Photobiology 2015-08-25

Discovery of a quaternary superconducting system Y-Ni-B-C has been reported recently. Our structural studies on ${\mathrm{YNi}}_{2}$${\mathrm{B}}_{2}$C (${\mathit{T}}_{\mathit{c}}$\ensuremath{\approxeq}15.5 K) reveal large and anisotropic thermal vibrations C atoms in the Y-C plane structure. No crystallographic phase transition is observed down to 50 K. specific-heat data suggest that strong-coupling superconductor. Results our resistivity, magnetic, clearly coexistence superconductivity...

10.1103/physrevb.51.489 article EN Physical review. B, Condensed matter 1995-01-01
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