A5087616433- Diabetes Treatment and Management
- Diabetes Management and Research
- Diabetes and associated disorders
- Metabolism, Diabetes, and Cancer
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pancreatic function and diabetes
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Systemic Sclerosis and Related Diseases
- Protease and Inhibitor Mechanisms
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cardiovascular Function and Risk Factors
- Blood Coagulation and Thrombosis Mechanisms
- Pharmacology and Obesity Treatment
- Gestational Diabetes Research and Management
- Cerebrovascular and Carotid Artery Diseases
- Skin Diseases and Diabetes
- Potassium and Related Disorders
- Lipoproteins and Cardiovascular Health
- Cardiovascular Issues in Pregnancy
- Atrial Fibrillation Management and Outcomes
- Maternal and fetal healthcare
- Bipolar Disorder and Treatment
- Hereditary Neurological Disorders
- Medication Adherence and Compliance
Institute of Experimental Endocrinology of the Slovak Academy of Sciences
2010-2024
Institute of Endocrinology
2016-2021
University of Ss. Cyril and Methodius in Trnava
2021
Národný Endokrinologický a Diabetologický Ústav
2017
Detská Fakultná Nemocnica s Poliklinikou
1997-2000
University Hospital
1998
Comenius University Bratislava
1996-1998
Martin University Hospital
1997
Ocní klinika
1995-1996
Abstract The disclosure of proven cardiorenal benefits with certain antidiabetic agents was supposed to herald a new era in the management type 2 diabetes (T2D), especially for many patients T2D who are at high risk cardiovascular and renal events. However, as evidence favour various sodium–glucose transporter-2 inhibitor (SGLT2i) glucagon-like peptide-1 receptor agonists (GLP-1 RA) accumulates, prescriptions these continue stagnate, even among eligible, at-risk patients. By contrast,...
The aim of the study was to determine level metabolic control in type 1 diabetes mellitus (T1DM) and 2 (T2DM) patients Czech Slovak Republics.A non-interventional prospective (observational) conducted from January 2015 until April 2016 routine clinical practice settings at 141 centers Republics. Data were analyzed a total 425 with T1DM 1034 T2DM, proportionally corresponding number both countries. primary objective percentage HbA1c < 7% (53 mmol/mol).Patients T1DM: In this group (55.8%...
For patients with type 2 diabetes (T2D), cardiovascular disease (CVD) is the single most common cause of mortality. In 2008 and 2012, Federal Drug Administration (FDA) European Medicines Agency (EMA) respectively mandated outcomes trials (CVOTs) on all new anti-diabetic agents, as prospective statistically powered to rule out excess risk in T2D. Unexpectedly, some these CVOTs have demonstrated not only safety, but also cardioprotective effects, was first shown for SGLT2 inhibitor...
The fixed-ratio combination (FRC) of a basal insulin and GLP-1 receptor agonist (GLP-1 RA) has proven to be an effective therapeutic approach. However, physicians face numerous practical questions that cannot answered by recently published trial results, current guidelines summaries product characteristics. In April 2019, scientific meeting was held with the participation nine experts from four Central Eastern European countries provide expert consensus on optimal daily use glargine...
This study aimed to evaluate the effectiveness and safety of switching from basal bolus insulin treatment (BBIT) a fixed combination degludec liraglutide (IDegLira) in patients with type 2 diabetes mellitus (T2DM) who had preserved secretion but inadequate glucose control. The also assess feasibility implementing this therapeutic approach common clinical practice settings.This was non-randomized, open-label, multicenter, prospective, single-arm involving 234 T2DM were receiving BBIT....
Purpose To evaluate the prevalence and epidemiological characteristics of diabetic retinopathy (DR) in Slovakian patients with Type 1 2 diabetes mellitus (DM) DIARET SK study. Patients methods An multi-center survey that included 4,078 adult (aged ≥18 years) from 51 diabetologists 47 ophthalmologists. Data were collected February to December 2015. Results The final data set consisted 4,014 patients; 3,700 enrolled (Type DM = 3,405, 295) using a quasi-random approach; 16 15, 1) pre-specified...
Individuals initially diagnosed with type 2 diabetes (T2D) might exhibit positivity for diabetes-associated autoantibodies (DAA +). We investigated the prevalence of DAA in a group individuals T2D who were referred to tertiary centre within pre-specified period time. aimed identify characteristics linked by comparing + their DAA-negative counterparts.This was cross-sectional study into which all patients National Institute Endocrinology and Diabetology, Ľubochňa, Slovakia, between 1 January...
Aims: The choice of insulin at initiation in type 2 diabetes remains controversial. aim this study was to assess the occurrence self-reported severe hypoglycaemia associated with premixed analogues routine clinical care. Methods: A 12-month, prospective, observational, multicentre patients starting a commonly prescribed analogue (either lispro 25/75 or biphasic aspart 30/70, twice daily) after suboptimal glycaemic control on oral antidiabetic agents. Treatment decisions were made solely...
The AIM of our work is to point out the relationship between insulin resistance and metabolic compensation diabetes mellitus, as well explore possibilities improving these parameters by non-drug measures.The rising incidence associated with many comorbidities, especially due increase in obesity unhealthy lifestyles, a serious medical problem today.It therefore necessary be able recognize evaluate presence resistance, prevent its occurrence, ensure elimination high-risk individuals.In study,...
Background: Despite the improvements in insulin therapy, a large number of patients fail to achieve their target glycated hemoglobin (HbA1c) levels. Control diabetes is often unsatisfactory because patient does not know about principles successful therapy (ie, blood glucose self-monitoring, administration, titration, current dose adjustments, dietary recommendations, and physical activity preventive measures) or these are applied incorrectly insufficiently. Furthermore, fear hypoglycemia may...
Chronic wounds result from the body's inability to heal, causing pain, pathogen entry, limited treatment options, and societal burden. Diabetic foot ulcers are particularly challenging, often leading severe complications like leg amputation. A clinical study tested AMNIODERM+
Despite the continuously improving treatment options, many patients with type 1 (T1DM) and 2 diabetes (T2DM) still do not achieve recommended goals. The article provides summary commentary of results DIAINFORM study focused on level metabolic control in T1DM T2DM treated insulin Czech Slovak Republics. overall percentage HbA1c 3 mmol/mol group was 29.9 % 33.4 %.
Type 2 diabetes mellitus is a heterogeneous medical condition involving multiple pathophysiological mechanisms. Its successful treatment requires an individualized approach and frequently combined therapy with utilizing its effect on levels. Current possibilities enable the employment of such procedures to incomparably greater extent than before. The effects different classes oral antidiabetic drugs reduction glycemia HbA1c mutually comparable. However differences are observed in proportions...
V snahe čo najširšej aplikácie aktuálnych poznatkov v diabetológii a príbuzných medicínskych odborov, s ohľadom na charakteristiky liekov aktuálne možnosti využívania moderných postupov, ale aj ich limitácie finančnými možnosťami zdravotných poisťovní, Slovenská diabetologická spoločnosť (SDS) pravidelne inovuje svoje terapeutické odporúčania pre liečbu diabetes mellitus. Posledné SDS vydala auguste roku 2016. prehľadovom článku sa diskutuje zdôvodňuje niekoľko faktorov, o ktoré autori...