A5066493498- Obstructive Sleep Apnea Research
- Tracheal and airway disorders
- Neuroscience of respiration and sleep
- Airway Management and Intubation Techniques
- Ear Surgery and Otitis Media
- Neonatal Respiratory Health Research
- Dysphagia Assessment and Management
- Glutathione Transferases and Polymorphisms
- Congenital Ear and Nasal Anomalies
- Cardiovascular and Diving-Related Complications
- Sulfur Compounds in Biology
- Head and Neck Surgical Oncology
- Congenital Heart Disease Studies
- Respiratory Support and Mechanisms
- Congenital Diaphragmatic Hernia Studies
- Redox biology and oxidative stress
- Respiratory and Cough-Related Research
- Otolaryngology and Infectious Diseases
- Foreign Body Medical Cases
- Mast cells and histamine
- Sleep and Wakefulness Research
- Gastroesophageal reflux and treatments
- Nasal Surgery and Airway Studies
- Analytical Chemistry and Chromatography
- Esophageal and GI Pathology
University of Colorado Anschutz Medical Campus
2003-2024
Children's Hospital Colorado
2015-2024
University of Colorado Denver
2015-2024
University of Colorado Health
2001-2024
Temple University
2024
Harvard University
2024
American Academy of Otolaryngology — Head and Neck Surgery
2024
University of Vermont Medical Center
2024
GTx (United States)
2022
In-Q-Tel
2022
Objective This update of a 2011 guideline developed by the American Academy Otolaryngology–Head and Neck Surgery Foundation provides evidence‐based recommendations on pre‐, intra‐, postoperative care management children 1 to 18 years age under consideration for tonsillectomy. Tonsillectomy is defined as surgical procedure performed with or without adenoidectomy that completely removes tonsil, including its capsule, dissecting peritonsillar space between tonsil capsule muscular wall. one most...
Objective. This guideline provides otolaryngologists with evidence‐based recommendations for using polysomnography in assessing children, aged 2 to 18 years, sleep‐disordered breathing and are candidates tonsillectomy, or without adenoidectomy. Polysomnography is the electrographic recording of simultaneous physiologic variables during sleep currently considered gold standard objectively disorders. Purpose. There no current consensus on when children years age, who recommended have...
Free AccessPosition StatementAmerican Academy of Sleep Medicine Position Paper for the Use a Home Apnea Test Diagnosis OSA in Children Valerie Kirk, MD, Julie Baughn, Lynn D'Andrea, Norman Friedman, Anjalee Galion, Susan Garetz, Fauziya Hassan, MS, Joanna Wrede, Christopher G. Harrod, Raman K. Malhotra, MD Address correspondence to: Department Pediatrics, Alberta Children's Hospital, Calgary, Alberta, Canada T3B6A8(403) 955-2397 E-mail Address: [email protected] University , Mayo Clinic,...
Previously, we reported that nitric oxide (NO) provides significant protection to mammalian cells from the cytotoxic effects of hydrogen peroxide (H2O2). Murine neutrophils and activated macrophages, however, produce NO, H2O2, other reactive oxygen species kill microorganisms, which suggests a paradox. In this study, treated bacteria (Escherichia coli) with NO H2O2 for 30 min found exposure resulted in minimal toxicity, but greatly potentiated (up 1,000-fold) H2O2-mediated killing, as...
Objective. The widespread use of antibiotics for treatment acute otitis media (AOM) has resulted in the emergence multidrug-resistant pathogens that are difficult to treat. However, it been shown most children with nonsevere AOM recover without ABX. objective this study was evaluate safety, efficacy, acceptability, and costs a non-ABX intervention AOM. Methodology. Children 6 months 12 years old were screened by using novel AOM-severity screening index. Parents received an educational...
Abstract Objectives: The American Academy of Pediatrics recommends objective testing with polysomnography (PSG) before adenotonsillectomy for sleep‐disordered breathing (SDB) in children. Several studies have also shown that a clinical diagnosis correlates poorly the presence or severity SDB as confirmed by PSG. purpose this study was to examine surgical practice patterns among members Society Pediatric Otolaryngologists (ASPO). Methods: A questionnaire sent electronically all ASPO asking...
A theoretical objection to ambient-temperature platelet storage is the possibility of proliferation micro-organisms introduced into system during phlebotomy or component preparation. After gram-negative septicemia followed infusion in two patients with cancer, a study was begun determine frequency contamination platelets stored at 25°C. Culture 2188 U platelets, pooled groups eight after storage, revealed bacteria more than 20 per cent pools; minimal individual units calculated be 2.4 cent....
Obstructive sleep apnea (OSA) is a common pediatric condition characterized by recurrent partial or complete cessation of airflow during sleep, typically due to inadequate upper airway patency. Continuous positive pressure (CPAP) therapeutic option that reduces morbidity. Despite efforts promote use, CPAP adherence poor in both and adult populations. We sought determine whether demographics, insurance status, OSA severity, pressure, comorbid conditions were associated with adherence.A...
Objective To develop an expert consensus statement on pediatric drug‐induced sleep endoscopy (DISE) that clarifies controversies and offers opportunities for quality improvement. Pediatric DISE was defined as flexible to examine the upper airway of a child with obstructive apnea who is sedated asleep. Methods Development group members expertise in followed established guidelines developing statements. A search strategist systematically reviewed literature, best available evidence used...
Abstract Objectives/Hypothesis: Obstructive sleep apnea (OSA) has been associated with upregulation of prothrombotic factors. We hypothesize that diagnosis OSA may be protective against postoperative hemorrhage. This study investigates the relationships between preoperative clinical and Study Design: Seven‐year retrospective case–control study. Methods: Medical records tonsillectomy subjects without hemorrhage were reviewed for demographics, diagnosis, treatment. Clinical diagnoses included...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCarbonium Ions. XI. Nuclear Magnetic Resonance Spectra of the Aliphatic Alkenyl CationsN. C. Deno, Herman G. Richey, Norman. Friedman, James D. Hodge, John J. Houser, and Charles U. PittmanCite this: Am. Chem. Soc. 1963, 85, 19, 2991–2995Publication Date (Print):October 1, 1963Publication History Published online1 May 2002Published inissue 1 October...
Obstructive sleep apnea (OSA) is common in children with Down syndrome (DS) and associated significant morbidity. In the current study we examined polysomnographic outcomes of DS who underwent tonsillectomy.
Objectives/Hypothesis The purpose of this investigation was to assess current drug‐induced sleep endoscopy (DISE) practice patterns at centers that have published on the technique, identify areas agreement, and disagreement may represent opportunities for improvement standardization. Study Design Multi‐institutional survey. Methods A survey designed in two phases evaluate preoperative assessment, intraoperative performance, postoperative management patients undergoing DISE. constructed...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCarbonium Ions. XIII. Ultraviolet Spectra and Thermodynamic Stabilities of Cycloalkenyl Linear Alkenyl CationsN. C. Deno, Joseph. Bollinger, Norman. Friedman, Karen. Hafer, James D. Hodge, John J. HouserCite this: Am. Chem. Soc. 1963, 85, 19, 2998–3000Publication Date (Print):October 1, 1963Publication History Published online1 May 2002Published inissue 1 October...
<h3>Objective</h3> To determine the efficacy of intracapsular tonsillectomy using low-temperature plasma excision for improving quality postoperative experience and treating obstructive symptoms through 12 months postoperatively. <h3>Design</h3> Prospective, randomized, controlled, single-blind study. <h3>Setting</h3> Multiple private or institutional otolaryngology clinics. <h3>Patients</h3> Fifty-five children (aged 3-12 years) with tonsillar hypertrophy. <h3>Intervention</h3> Patients...