A5053824233- Muscle Physiology and Disorders
- Nasal Surgery and Airway Studies
- Tracheal and airway disorders
- Exercise and Physiological Responses
- Allergic Rhinitis and Sensitization
- Respiratory and Cough-Related Research
- Vestibular and auditory disorders
- Airway Management and Intubation Techniques
- Otolaryngology and Infectious Diseases
- Pancreatic function and diabetes
- Muscle activation and electromyography studies
- Sinusitis and nasal conditions
- Obstructive Sleep Apnea Research
- Ear Surgery and Otitis Media
- Digital Imaging in Medicine
- Asthma and respiratory diseases
- Neuroscience of respiration and sleep
- Amyotrophic Lateral Sclerosis Research
- Diabetes Management and Research
- Clinical practice guidelines implementation
- Cardiac, Anesthesia and Surgical Outcomes
- Metabolism and Genetic Disorders
- Adipose Tissue and Metabolism
- Congenital Diaphragmatic Hernia Studies
- Diabetes and associated disorders
Eight19 (United Kingdom)
2024
Imperial College London
2024
University of Saskatchewan
2023
Great Ormond Street Hospital for Children NHS Foundation Trust
2013-2022
Consumers Union
2015-2020
Zero Breast Cancer
2016
Queen's University Belfast
2008
University of California, Davis
1992-2005
University of California Davis Medical Center
2005
Muscular Dystrophy Association
2002
Objective This update of a 2004 guideline codeveloped by the American Academy Otolaryngology—Head and Neck Surgery Foundation, Pediatrics, Family Physicians, provides evidence‐based recommendations to manage otitis media with effusion (OME), defined as presence fluid in middle ear without signs or symptoms acute infection. Changes from prior include consumer advocates added group, evidence 4 new clinical practice guidelines, 20 systematic reviews, 49 randomized control trials, enhanced...
Objective This update of a 2007 guideline from the American Academy Otolaryngology—Head and Neck Surgery Foundation provides evidence‐based recommendations to manage adult rhinosinusitis, defined as symptomatic inflammation paranasal sinuses nasal cavity. Changes prior include consumer added group, evidence 42 new systematic reviews, enhanced information on patient education counseling, algorithm clarify action statement relationships, expanded opportunities for watchful waiting (without...
Objective Allergic rhinitis (AR) is one of the most common diseases affecting adults. It chronic disease in children United States today and fifth overall. AR estimated to affect nearly 1 every 6 Americans generates $2 $5 billion direct health expenditures annually. can impair quality life and, through loss work school attendance, responsible for as much $4 lost productivity Not surprisingly, myriad diagnostic tests treatments are used managing this disorder, yet there considerable variation...
Objective This update of a 2011 guideline developed by the American Academy Otolaryngology–Head and Neck Surgery Foundation provides evidence‐based recommendations on pre‐, intra‐, postoperative care management children 1 to 18 years age under consideration for tonsillectomy. Tonsillectomy is defined as surgical procedure performed with or without adenoidectomy that completely removes tonsil, including its capsule, dissecting peritonsillar space between tonsil capsule muscular wall. one most...
Objective Ménière’s disease (MD) is a clinical condition defined by spontaneous vertigo attacks (each lasting 20 minutes to 12 hours) with documented low‐ midfrequency sensorineural hearing loss in the affected ear before, during, or after one of episodes vertigo. It also presents fluctuating aural symptoms (hearing loss, tinnitus, fullness) ear. The underlying etiology MD not completely clear, yet it has been associated inner fluid (endolymph) volume increases, culminating episodic...
The American Academy of Otolaryngology—Head and Neck Surgery Foundation has published a supplement to this issue featuring the updated “Clinical Practice Guideline: Adult Sinusitis” as Otolaryngology–Head . To assist in implementing guideline recommendations, article summarizes rationale, purpose, key action statements. 14 developed recommendations address diagnostic accuracy for adult rhinosinusitis, appropriate use ancillary tests confirm diagnosis guide management (including radiography,...
The American Academy of Otolaryngology—Head and Neck Surgery Foundation (AAO‐HNSF) has published a supplement to this issue featuring the new Clinical Practice Guideline: Allergic Rhinitis. To assist in implementing guideline recommendations, article summarizes rationale, purpose, key action statements. 14 recommendations developed address evaluation patients with allergic rhinitis, including performing interpretation diagnostic testing assessment documentation chronic conditions...
The American Academy of Otolaryngology—Head and Neck Surgery Foundation has published a supplement to this issue featuring the updated “Clinical Practice Guideline: Otitis Media with Effusion.” To assist in implementing guideline recommendations, article summarizes rationale, purpose, key action statements. 18 recommendations developed emphasize diagnostic accuracy, identification children who are most susceptible developmental sequelae from otitis media effusion, education clinicians...
Objective Rhinoplasty, a surgical procedure that alters the shape or appearance of nose while preserving enhancing nasal airway, ranks among most commonly performed cosmetic procedures in United States, with >200,000 reported 2014. While it is difficult to calculate exact economic burden incurred by rhinoplasty patients following surgery without complications, average typically exceeds $4000. The costs due infections, revision may include cost long‐term antibiotics, hospitalization, lost...
Ménière's disease (MD) is a clinical condition defined by spontaneous vertigo attacks (each lasting 20 minutes to 12 hours) with documented low- midfrequency sensorineural hearing loss in the affected ear before, during, or after one of episodes vertigo. It also presents fluctuating aural symptoms (hearing loss, tinnitus, fullness) ear. The underlying etiology MD not completely clear, yet it has been associated inner fluid volume increases, culminating episodic (vertigo, and fullness)....
Objective Rhinoplasty, a surgical procedure that alters the shape or appearance of nose while preserving enhancing nasal airway, ranks among most commonly performed cosmetic procedures in United States, with >200,000 reported 2014. While it is difficult to calculate exact economic burden incurred by rhinoplasty patients following surgery without complications, average typically exceeds $4000. The costs due infections, revision may include cost long‐term antibiotics, hospitalization, lost...
To understand how exercise affects the contractile function of dystrophic muscle, we examined effect long-term voluntary on mdx mice and related these effects to our findings in sedentary aging mice. Although mouse is genetic homolog for Duchenne muscular dystrophy, it does not demonstrate same progression limb muscle dysfunction as dystrophy ages. We postulated that lifestyle this animal plays an important role its minimal phenotypic expression. examine exercise, eight C57BL/10 (C57) were...
Data Abstraction Assistant (DAA) is a software for linking items abstracted into data collection form systematic review to their locations in study report. We conducted randomized cross-over trial that compared DAA-facilitated single-data abstraction plus verification ("DAA verification"), single ("regular and independent dual adjudication ("independent abstraction"). This an online with 26 pairs of abstractors. Each pair from six articles, two per approach. Outcomes were the proportion...
This plain language summary serves as an overview in explaining earwax (cerumen). The applies to patients older than 6 months with a clinical diagnosis of impaction and is based on the 2017 update Clinical Practice Guideline: Earwax (Cerumen Impaction). evidence‐based guideline includes research that supports treatment impaction. was developed improve care by health providers for managing creating clear recommendations use medical practice.
The Skin Investigation Network of Canada (SkIN Canada) is a new national skin research network. To shape the landscape and ensure its value to patient care, priorities that are important patients, caregivers, health care providers must be identified.To identify Top Ten for 9 key conditions.We first surveyed researchers select top conditions future within categories inflammatory disease, cancers (other than melanoma), wound healing. For those selected conditions, we conducted scoping reviews...
Objective This plain language summary serves as an overview in explaining otitis media with effusion (pronounced Oh‐TIE‐tis ME‐dee‐uh Ef‐YOO‐zhun), abbreviated “OME” and often called “ear fluid.” The applies to children aged 2 months through 12 years OME is based on the 2015 “Clinical Practice Guideline: Otitis Media Effusion (Update).” evidence‐based guideline includes research support more effective diagnosis treatment of children. was developed a quality improvement opportunity for...
Data abstraction, a critical systematic review step, is time-consuming and prone to errors. Current standards for approaches data abstraction rest on weak evidence base. We developed the Abstraction Assistant (DAA), novel software application designed facilitate process by allowing users (1) view study article PDFs juxtaposed electronic forms linked system, (2) highlight (or “pin”) location of text in PDF, (3) copy relevant from PDF into form. describe design randomized controlled trial...
ADAR2 transgenic mice misexpressing the RNA editing enzyme (Adenosine Deaminase that act on RNA) show characteristics of overeating and experience adult onset obesity. Behavioral patterns brain changes related to a possible addictive in these were explored as display chronic hyperphagia. assessed their food preference motivation overeat competing reward environment with ad lib access running wheel food. Metabolic activity peripheral tissue [(18) F] fluorodeoxyglucose positron emission...