A5016449773- Airway Management and Intubation Techniques
- Cardiac electrophysiology and arrhythmias
- Tracheal and airway disorders
- Ion channel regulation and function
- Respiratory Support and Mechanisms
- Electrochemical sensors and biosensors
- Analytical Chemistry and Sensors
- Neuroscience and Neuropharmacology Research
- Electrochemical Analysis and Applications
- Anesthesia and Sedative Agents
- Cardiac Arrhythmias and Treatments
- Anesthesia and Pain Management
- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Atrial Fibrillation Management and Outcomes
- Head and Neck Surgical Oncology
- Infection Control and Ventilation
- Cardiac Ischemia and Reperfusion
- Neuroscience and Neural Engineering
- Conducting polymers and applications
- Cardiac, Anesthesia and Surgical Outcomes
- Gas Sensing Nanomaterials and Sensors
- Anesthesia and Neurotoxicity Research
- Pain Management and Opioid Use
- Venous Thromboembolism Diagnosis and Management
Hualien Tzu Chi Medical Center
2017-2024
Providence University
2008-2024
Broadcom (United States)
2023
Tzu Chi Foundation
2021-2022
National Yang Ming Chiao Tung University
1996-2021
National Yang Ming University Hospital
2021
China Medical University Beigang Hospital
2013-2017
China Medical University
2013-2017
Genomics (United Kingdom)
2016
China Medical University Hospital
2015
Background Propofol may exert negative inotropic and chronotropic actions in the heart. Single-channel studies show that propofol affects kinetics of opening closing cardiac L-type calcium channels (ICa(L)) without altering channel conductance. The aim this study was to investigate mechanisms depressant effects on whole-cell ICa(L). Methods Single ventricular myocytes were freshly dissciated from guinea pig hearts using enzymatic isolation. One-suction electrode voltage-clamp technique...
Induction of anesthesia can be challenging for patients with difficult airways and head or neck tumors. Factors that could complicate airway management include poor dentition, limited mouth opening, restricted motility, narrowing oral space, laryngeal pharyngeal obstruction glottic regions from the tumor. Current guidelines awake tracheal intubation, anesthetized combined intubation. Video laryngoscopy is often chosen over direct in because an improved view, higher frequency successful...
Abstract Habitual chewing of areca nut increases the risk cardiovascular disease mortality, but less report demonstrate toxic mechanism on heart. To investigate toxicity cardiomyocytes, we induced heart injury with arecoline to evaluate acute damage Different concentrations are coline (lowdosage: 5 mg/kg/day and high dosage 50 mg/kg/day) were injected into Sprague‐Dawley rat via intra‐peritoneal method for 21 days create negative effects cardiomyocyte. Themyocardial architecture was...
Laryngoscopy for tracheal intubation has been developed many decades. Among various conventional laryngoscopes, videolaryngoscopes (VLs) have applied in different patient populations, including difficult airways. The safety and effectiveness of VLs repeatedly studied both normal superiority then observed is advocated as the standard care. In contrast to laryngoscopy, development video-assisted intubating stylet (VS, also named styletubation) was noticed two decades ago. Since then, sporadic...
Objective To investigate the roles of nitric oxide and adenosine triphosphate (ATP)-sensitive potassium channels (KATP) in shortening cardiac action potential endotoxic shock. Design Prospective animal study with concurrent controls. Setting University research laboratory. Subjects Adult Hartley guinea pigs, weighing 300–400 g. Interventions Guinea pigs were anesthetized mechanically ventilated for 6 hrs. Lipopolysaccharide (LPS) or saline (sham group) given intravenously. Drug effects...
The present experiments were designed to study the cellular mechanism responsible for depressant effects of halothane and isoflurane on human atrial tissues obtained at cardiac surgery. fibers superfused in Tyrode's solution, transmembrane potentials recorded with a microelectrode technique. In showing fast response action potential (maximum velocity depolarization [Vmax] greater than 100 V/s), (0.75 vol%, 0.44 mM) (1.25 0.53 decreased slightly upstroke but depressed plateau twitch force...
Background. Perioperative normovolemic anemia was applied in pediatric living-donor liver transplant (LDLT) recipients with the aim of reducing use blood products and decreasing transfusion-related risk. Methods. The anemic state allowed to occur by replacing intraoperative transudate loss colloid solutions a discriminate packed red cells. When transfusion required, amount replacement calculated target hemoglobin level not higher than 8 9 g/dL. Results. Forty-eight patients underwent LDLT....
Since its outbreak in China, the Coronavirus disease 2019 (COVID-19) pandemic has caused worldwide disaster. Globally, there have been 71,581,532 confirmed cases of COVID-19, including 1,618,374 deaths, reported to World Health Organization (data retrieved on December 16, 2020). Currently, no treatment modalities for COVID-19 (e.g., vaccines or antiviral drugs) with efficacy and safety are available. Although possibilities relevant challenges some alternatives use stem cells as...
We consider in this work hexagonal grids for two-dimensional applications. A finite volume-based difference approach to solving Laplacian-related differential equations on is developed. Both ordinary and compact seven-point schemes are investigated. Theoretical properties of the associated linear algebraic systems determined. These methods applied solve PDEs both regular curved domains, successfully exhibiting spiral wave propagations domains a reversed C-type domain.
Tracheal intubation and ventilatory support are among the important treatments in patients infected with COVID-19 acute respiratory distress syndrome (ARDS) severe hypoxia. The intubating team often uses video-assisted equipment to ensure a safe successful tracheal intubation. In this case report, we demonstrate for first time, use of Shikani stylet technique as safe, speedy, effective way intubate critically ill highly contagious patient. addition conventional consensus guidelines that...
As the COVID-19 pandemic evolves, infection with Omicron variants has become a serious risk to global public health. Anesthesia providers are often called upon for endotracheal intubations COVID patients. Expedite and safe intubation can save patient's life, while minimizing virus exposure anesthesia provider personnel involved during airway intervention is very important protect healthcare workers conserve medical work force. In this paper, we share clinical experience of using...
Direct laryngoscopy and videolaryngoscopy are currently the dominant tools for endotracheal intubation. However, video-assisted intubating stylet, a type of videolaryngoscopy, has been shown to offer some advantages over these tools, such as rapid intubation time, high first-attempt success rates, less airway stimulation, subjective satisfaction. On other hand, this optical technique also technical limitations that need be addressed, including camera lens fogging, path disorientation,...