A5100619537- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiovascular Effects of Exercise
- Heart Rate Variability and Autonomic Control
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Function and Risk Factors
- Cardiomyopathy and Myosin Studies
- Sports injuries and prevention
- Blood Pressure and Hypertension Studies
- Cardiac Imaging and Diagnostics
- Sepsis Diagnosis and Treatment
- Heart Failure Treatment and Management
- Viral Infections and Immunology Research
- Cardiac Arrest and Resuscitation
- Venous Thromboembolism Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- ECG Monitoring and Analysis
- Cardiac Valve Diseases and Treatments
- Genetic Associations and Epidemiology
- Simulation and Modeling Applications
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Respiratory Support and Mechanisms
- Cardiovascular Issues in Pregnancy
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025
Shaoxing University
2025
Shandong University of Traditional Chinese Medicine
2025
Fu Wai Hospital
2014-2024
Peking Union Medical College Hospital
2011-2024
Beijing Anzhen Hospital
2013-2024
First Hospital of China Medical University
2024
Second Affiliated Hospital of Zhejiang University
2024
China Medical University
2024
Capital Medical University
2013-2024
Background: Catheter ablation as first-line therapy for ventricular tachycardia (VT) at the time of implantable cardioverter defibrillator (ICD) implantation has not been adopted into clinical guidelines. Also, there is an unmet need to prospectively examine role VT in patients with nonischemic cardiomyopathy, increasingly prevalent population that referred advanced therapies globally. Methods: We conducted international, multicenter, randomized controlled trial enrolling 180 cardiomyopathy...
The stress hyperglycemia ratio (SHR) has demonstrated a noteworthy association with unfavorable cardiovascular clinical outcomes and heightened in-hospital mortality. Nonetheless, this relationship in critically ill patients remains uncertain. This study aims to elucidate the correlation between SHR patient prognosis within critical care setting.A total of 8978 admitted intensive unit (ICU) were included study. We categorized into uniform groups assessed its mortality using logistic or Cox...
Abstract Background and Aims It remains unknown whether the brain glymphatic system, which is driven by heartbeat-driven pulsation of arteries responsible for cerebral waste clearance, impaired in atrial fibrillation (AF) mediates cognitive dysfunction related to AF. The aim this study was assess alterations AF, their role function, catheter ablation can improve activity. Methods In case-control prospective before–and–after study, patients with AF healthy controls (HCs) were enrolled....
Vasovagal syncope (VVS) is the most common cause of recurrent that can be debilitating despite optimal conventional therapy. The aim this study was to evaluate feasibility and efficacy selective endocardial autonomic denervation in left atrium (LA) as an alternative treatment strategy patients with highly symptomatic VVS.Ten consecutive (mean age, 50.4±6.4 years; 7 women) a medium 3.5 (range, 2-20) episodes VVS during preceding year positive head-up tilt testing whom standard therapies were...
Cardiac tamponade is the most dramatic complication observed during atrial fibrillation (AF) ablation and leading cause of procedure-related mortality. Female sex a known risk factor for complications AF ablation; however, it unknown whether women have higher tamponade.A systematic Medline search was used to locate academic electrophysiological centers that reported cases occurring ablation. Centers were asked provide information on acute according their mode management including any case...
Abstract Aims This multicentre observational study aimed to prospectively assess the efficacy of left bundle branch area pacing (LBBAP) in heart failure patients with block (LBBB) and compare 6‐month outcomes between LBBAP biventricular (BVP). Methods results Consecutive LBBB ventricular ejection fraction (LVEF) ≤ 35% were recruited if they had undergone as a primary or rescue strategy from three separate centres March December 2018. Patients who received BVP 2018 retrospectively selected by...
A packaged self-powered system by hybridizing nanogenerators (PSNGS) is demonstrated. The performance of the PSNGS tested in a biofluid and used for powering an electronic thermometer. Select waterproof universal connectors are designed fabricated energy signal transmission. This can significantly advance development implanted medical devices wearable/portable electronics.
Background Autonomic modification through catheter ablation of ganglionated plexi ( GPs ) in the left atrium has been reported previously as a treatment for vasovagal syncope. This study aimed to observe long‐term outcome larger cohort. Methods and Results A total 57 consecutive patients (aged 43.2±13.4 years; 35 women) with refractory syncope were enrolled, high‐frequency stimulation anatomically guided GP performed 10 47 cases, respectively. 127 sites positive vagal response successfully...
Hypertrophic cardiomyopathy (HCM) is a common heritable heart disease. Although HCM has been reported to be associated with many variants of genes involved in sarcomeric protein biomechanics, pathogenic have not identified patients partial HCM. FARS2 (the mitochondrial phenylalanyl-tRNA synthetase), type aminoacyl-tRNA synthetase, plays role the translation machinery. Several
Background The effect of alcohol consumption on substrate remodeling and ablation outcome paroxysmal atrial fibrillation ( PAF ) remains unknown. Methods Results We performed circumferential pulmonary vein isolation CPVI voltage mapping left atrium LA during sinus rhythm in 122 consecutive patients with symptomatic (age, 55.4±9.4 years; 73.8% men). Low‐voltage zones LVZ s) were semiquantitatively estimated presented as low‐voltage index LVI ). Each patient's daily history was recorded at...
Recently, a triboelectric generator (TEG) has been invented to convert mechanical energy into electricity by conjunction of triboelectrification and electrostatic induction. Compared the traditional electromagnetic (EMG) that produces high output current but low voltage, TEG different characteristics voltage. In this paper, we present comparative study regarding fundamentals TEGs EMGs. The power performances EMG have special complementary relationship, with being voltage source source....
There has been increasing attention on immune-oncology for its impressive clinical benefits in many different malignancies. However, due to molecular and genetic heterogeneity of tumors, the activities traditional pathological criteria are far from satisfactory. Immune-based strategies have re-ignited hopes treatment prevention breast cancer. Prognostic or predictive biomarkers, associated with tumor immune microenvironment, may great prospects guiding patient management, identifying new...
To investigate whether left bundle branch area pacing (LBBAP) can reduce the risk of new-onset atrial fibrillation (AF) compared with right ventricular (RVP).Patients indications for dual-chamber pacemaker implant and no history AF were prospectively enrolled if they underwent successful LBBAP or RVP. The primary endpoint was time to first occurrence detected by programming surface electrocardiogram. Follow-up at clinic visit performed multivariate Cox regression models applied evaluate...
Endocardial Mapping and Ablation of Brugada Syndrome.Brugada syndrome (BS) is characterized by ST-segment elevation in the right precordial electrocardiogram (ECG) leads episodes ventricular fibrillation (VF). This study aimed to observe feasibility substrate modification radiofrequency catheter ablation its effects on VF storm.Ten BS patients (all men; median age 36.5 years) with storm (group I, n = 4) no II, 6) were enrolled between August 2007 December 2008. All underwent...
Background— Although mutations of several genes are associated with arrhythmogenic right ventricular cardiomyopathy (ARVC), the exact correlation between genotype and arrhythmia features remains unclear. This study was aimed to examine possible association 9 known ARVC clinical electrophysiological characteristics. Methods Results— Ninety subjects diagnosed who underwent were recruited for screening ARVC-causing genes. A total 53 identified in 57 (63%) subjects. Mutation carriers had more...
Arrhythmogenic cardiomyopathy (ACM) is a myocardial disease caused mainly by mutations in genes encoding desmosome proteins ACM patients present with ventricular arrhythmias, cardiac dysfunction, sudden death, and subset fibro-fatty infiltration of the right ventricle predominantly. Endurance exercise thought to exacerbate dysfunction arrhythmias ACM. The objective was determine effects treadmill on phenotype, including myocyte gene expression myocyte-specific desmoplakin (Dsp)...
Background: Left bundle branch area pacing (LBBAP) is a novel modality with stable parameters and narrow-paced QRS duration. We compared heart failure (HF) hospitalization events echocardiographic measures between LBBAP right ventricular (RVP) in patients atrioventricular block (AVB). Methods Results: This multicenter observational study prospectively recruited consecutive AVB requiring five centers if they received or RVP had left ejection fraction (LVEF) >50%. Data on...