A5008865996- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Heart Rate Variability and Autonomic Control
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Cardiovascular Effects of Exercise
- Cardiomyopathy and Myosin Studies
- Venous Thromboembolism Diagnosis and Management
- Advanced MRI Techniques and Applications
- Infective Endocarditis Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Viral Infections and Immunology Research
- Acute Ischemic Stroke Management
- Cardiovascular and Diving-Related Complications
- Neurological disorders and treatments
- Schizophrenia research and treatment
- Heart Failure Treatment and Management
- Blood Pressure and Hypertension Studies
- ECG Monitoring and Analysis
- Acute Myocardial Infarction Research
Massachusetts General Hospital
2016-2025
Harvard University
2015-2024
Shanghai Changzheng Hospital
2022
Boston Medical Center
2005-2022
University Medical Center
2022
Boston University
1978-2022
Kaiser Permanente
2022
Maastricht University
2022
Acorda Therapeutics (United States)
2022
Beijing University of Chinese Medicine
2022
During the past decade, catheter ablation of atrial fibrillation (AF) has evolved rapidly from an investigational procedure to its current status as a commonly performed in many major hospitals throughout world. Surgical AF, using either standard or minimally invasive techniques, is also world. In 2007, initial Consensus Statement on Catheter and AF Ablation was developed joint effort Heart Rhythm Society, European Association, Cardiac Arrhythmia Society.1 The 2007 document collaboration...
For patients who have a ventricular tachyarrhythmic event, implantable cardioverter-defibrillators (ICDs) are mainstay of therapy to prevent sudden death. However, ICD shocks painful, can result in clinical depression, and do not offer complete protection against death from arrhythmia. We designed this randomized trial examine whether prophylactic radiofrequency catheter ablation arrhythmogenic tissue would reduce the incidence therapy.Eligible with history myocardial infarction underwent...
There are few data regarding the determinants of sudden cardiac death (SCD) in women, primarily because their markedly lower rate SCD compared with men. Nonetheless, existing data, although sparse, suggest possible gender differences risk factors for SCD.In this prospective cohort 121 701 women aged 30 to 55 years at baseline, was defined as within 1 hour symptom onset. From 1976 1998, 244 SCDs were identified. Although increased age, percentage deaths that decreased. Most (69%) who suffered...
SELENIUM is a trace element that until recently has been considered unimportant in human nutrition, except when ingested excessive amounts.1 During the past decade, Chinese investigators have shown selenium deficiency one of principal factors responsible for Keshan disease, "dilated" (congestive) cardiomyopathy affects persons (mainly children and young women) living rural areas selenium-deficient zone China.2 3 4 This report describes an Occidental patient whom became associated with...
Effect of Ablation Electrode Contact Force. Introduction: electrode–tissue contact has been shown to be an important determinant lesion size and safety during nonirrigated ablation but little data are available irrigated ablation. We aimed determine the importance force irrigated‐tip Methods Results: Freshly excised hearts from 11 male pigs were perfused superfused using fresh, heparinized, oxygenated swine blood in ex vivo model. One‐minute ablations placed one 3 different power control...
Curved surfaces, complex geometries, and time-dynamic deformations of the heart create challenges in establishing intimate, nonconstraining interfaces between cardiac structures medical devices or surgical tools, particularly over large areas. We constructed area designs for diagnostic therapeutic stretchable sensor actuator webs that conformally wrap epicardium, robust contact without sutures, mechanical fixtures, tapes, adhesives. These multifunctional web exploit open, mesh layouts mount...
Bioprinting has emerged as a promising tool in tissue engineering and regenerative medicine. Various 3D printing strategies have been developed to enable bioprinting of various biopolymers hydrogels. However, the incorporation biological factors not well explored. As importance personalized medicine is becoming more clear, need for development bioinks containing autologous/patient-specific applications becomes evident. Platelet-rich plasma (PRP) used patient-specific source autologous growth...
<h3>Background</h3> Atrial fibrillation is the most common cardiac arrhythmia associated with significant medical complications. We examined trends in therapy of atrial United States from 1991 through 2000. <h3>Methods</h3> Data 1355 visits among patients were obtained National Ambulatory Medical Care Survey, a nationally representative assessment office-based practice. assessed medication use for ventricular rate control (digoxin, β-blockers, and calcium channel blockers), sinus rhythm...
BACKGROUND Recurrent sustained ventricular tachycardia (VT) is not responsive to antiarrhythmic drugs in the majority of patients, who therefore need therapy with nonpharmacological methods. We evaluated prospectively feasibility, safety, and efficacy transcatheter radiofrequency (RF) ablation VT 21 selected patients ischemic heart disease VT. METHODS AND RESULTS Twenty-one recurrent, drug-refractory documented by 12-lead ECG were had sufficient hemodynamic tolerance undergo mapping....
Important sex differences in the epidemiology of sudden death and results electrophysiological testing survivors cardiac arrest have been identified. These are currently poorly understood.Three hundred fifty-five consecutive out-of-hospital (84 women 271 men) referred for electrophysiologically guided therapy were analyzed retrospectively underlying pathology predictors outcome. Women significantly less likely to coronary artery disease than men (45% versus 80%) more other forms heart or...
Pulmonary vein (PV) isolation for atrial fibrillation (AF) currently is performed using either an ostial or extra-ostial approach. The objective of this study was to analyze by three-dimensional (3D) magnetic resonance angiography (MRA) the anatomy PVs in order detect structural variability that would impact choice ablation approach.Three-dimensional MRA 105 patients undergoing PV isolation. diameter, branching pattern, and angulation were analyzed. Fifty-nine (56%) had typical pattern 4...