A5041540531- 3D Printing in Biomedical Research
- Adsorption and biosorption for pollutant removal
- Carbon Dioxide Capture Technologies
- Bone Tissue Engineering Materials
- Peripheral Artery Disease Management
- Biomedical Ethics and Regulation
- Microfluidic and Capillary Electrophoresis Applications
- Cerebrovascular and Carotid Artery Diseases
- Innovative Microfluidic and Catalytic Techniques Innovation
- Dendrimers and Hyperbranched Polymers
- Electrospun Nanofibers in Biomedical Applications
- Carbon dioxide utilization in catalysis
- Nanoparticle-Based Drug Delivery
- Venous Thromboembolism Diagnosis and Management
- CO2 Reduction Techniques and Catalysts
- Covalent Organic Framework Applications
- Catalytic Cross-Coupling Reactions
- Digital Imaging in Medicine
- Mesenchymal stem cell research
- Conducting polymers and applications
- Nanocomposite Films for Food Packaging
- Organ Transplantation Techniques and Outcomes
- Nanoplatforms for cancer theranostics
- Angiogenesis and VEGF in Cancer
- Cancer, Hypoxia, and Metabolism
Nationwide Children's Hospital
2022-2024
Rowan University
2019-2022
East Carolina University
2020
Innovation Research Center
2016-2018
Brigham and Women's Hospital
2016-2018
Harvard University
2016-2018
Harvard–MIT Division of Health Sciences and Technology
2016-2018
Massachusetts Institute of Technology
2016-2018
Sahand University of Technology
2016-2018
Amirkabir University of Technology
2017
Abstract Chronic wounds do not heal in an orderly fashion part due to the lack of timely release biological factors essential for healing. Topical administration various therapeutic at different stages is shown enhance healing rate chronic wounds. Developing a wound dressing that can deliver biomolecules with predetermined spatial and temporal pattern would be beneficial effective treatment Here, actively controlled fabricated using composite fibers core electrical heater covered by layer...
Bioprinting has emerged as a promising tool in tissue engineering and regenerative medicine. Various 3D printing strategies have been developed to enable bioprinting of various biopolymers hydrogels. However, the incorporation biological factors not well explored. As importance personalized medicine is becoming more clear, need for development bioinks containing autologous/patient-specific applications becomes evident. Platelet-rich plasma (PRP) used patient-specific source autologous growth...
There is a growing interest to develop microfluidic bioreactors and organ-on-chip platforms with integrated sensors monitor their physicochemical properties maintain well-controlled microenvironment for cultured organoids. Conventional sensing devices cannot be easily systems low-volume continual monitoring. This paper reports on the development of multi-analyte optical module dynamic measurements pH dissolved oxygen levels in culture medium. The system was constructed using low-cost...
Abstract Advancements in congenital heart surgery have heightened the importance of durable biomaterials for adult survivors. Dystrophic calcification poses a significant risk to long-term viability prosthetic these procedures. Herein, we describe natural history most frequently used vascular conduits, expanded polytetrafluoroethylene grafts. Through retrospective clinical study and an ovine model, compare degree between tissue-engineered grafts Results indicate superior durability grafts,...
The positive response of superparamagnetic iron oxide nanoparticles (SPIONs), in terms biodegradability, circulation, elimination, toxicity, and manipulation their structure/activity relationship, has enabled them to find way into commercialization as an supplement, MRI contrast agents, MPI tracers, hyperthermia magneto-mechanical actuators. This Review focuses on the most current progress regarding application SPIONs magnetic therapeutic agents for cancer treatment tissue engineering....
Background Perfusion deficits contribute to symptom severity, morbidity, and death in peripheral artery disease (PAD); however, no standard method for quantifying absolute measures of skeletal muscle perfusion exists. This study sought preclinically test clinically translate a positron emission tomography (PET) imaging approach using an atherosclerosis‐targeted radionuclide, fluorine‐18‐sodium fluoride ( 18 F‐NaF), quantify PAD. Methods Results Eight Yorkshire pigs underwent unilateral...
Introduction: The increase in greenhouse gas levels and the gradual warming of earth have garnered worldwide interest. enzyme formate-dehydrogenase can reduce CO2 by converting it into formate, which is subsequently converted methanol alcohol dehydrogenase. purpose this research was to evaluate effect different concentrations IPGT, modifier, induction time culture medium on expression optimization. Methods: Specific primers were designed amplify gene fragment using polymerase chain reaction...
Influence of gelatine concentration and cross-linker ions Ca2+ Ba2+ was evaluated on characteristics alginate hydrogels proliferation behaviours model adherent suspendable stem cells fibroblast U937 embedded in microcapsules. Increasing to 2.5% increased extent swelling 15% 25% for barium- calcium-cross-linked hydrogels, respectively. Mechanical properties also decreased with increasing hydrogels. Both by using barium considerably the encapsulated cells. Barium-cross-linked alginate-gelatine...
The aim of this study was to evaluate the adsorption capacity novel coated activated carbon by chitosan for removal Cr (VI) and Cd (II) ions from single bi-solute dilute aqueous solutions. In addition, abilities (AC), (CH) / composite (CHAC) have been compared. Adsorption studies were performed in a batch system, effects various operating parameters such as solution pH, particle size dose adsorbent considered Taguchi method. Equilibrium experimental data well fitted Langmuir isotherm...
A heterogenous Palladium anchored Resorcinol-formaldehyde-hyperbranched PEI mesoporous catalyst, made by one-pot synthesis, was used successfully for in situ Suzuki-Miyaura cross coupling synthesis of anticancer prodrug PP-121 from iodoprazole and boronic ester precursors. The catalyst with the non-cytotoxic precursors were tested 2D vitro model excellent cytocompatibility a strong suppression PC3 cancer cell proliferation, underscored 50% reduction cells viability 55% metabolism activity an...
In article 1701347 by Ali Tamayol and co-workers, alginate-based bioinks are developed that carry platelet rich plasma (PRP) as a source of growth factors compatible with commercial bioprinters. The use autologous PRP in the is an important step towards bioprinting patient specific tissues scaffolds. Cover image designed produced Masoud Moosavi Basri.
Positron emission tomography (PET)/computed (CT) imaging can detect changes in arterial inflammation, but has not been used to evaluate chemotherapy-induced venous inflammation or assess risk for thromboembolism (VTE) pediatric oncology. Therefore, the purpose of this study was prognostic value fluorine-18-fluorodeoxyglucose PET/CT predicting VTE occurrence 12 months after lymphoma diagnosis pediatric, adolescent, and young adult patients.Pediatric, patients with diagnoses (n=71) who...
To address the issue of global warming and climate change issues, recent research efforts have highlighted opportunities for capturing electrochemically converting carbon dioxide (CO2). Despite metal doped polymers receiving widespread attention in this respect, structures hitherto reported lack ease synthesis with scale up feasibility. In study, a series mesoporous metal-doped (MRFs) tunable functionality hierarchical porosity were successfully synthesized using one-step copolymerization...
This work explores the novel one-pot aqueous phase synthesis of mesoporous phenolic-hyperbranched polyethyleneimine resins without use a template, and their utility as heterogeneous catalysts in batch reactors continuous microreactors. Catalyst surface areas up to 432 m2/g were achieved with uniform Pd distribution an interconnected, highly porous, network structure, confirmed through Brunauer–Emmett–Teller (BET) area measurements, scanning electron microscopes (SEM), X-Ray Photoelectron...
Microcomputed tomography (microCT) angiography is an invaluable resource to researchers. New advances in this technology have allowed for high-quality images be obtained of micro-vasculature and are high-fidelity tools the field organ transplantation. In model orthotopic liver transplantation (OLT) mice, microCT affords opportunity evaluate allograft anastomosis real time has added benefit not having sacrifice study animals. The choice contrast, as well image acquisition settings, create a...
Background: Similarities in peripheral vascular anatomy between swine and humans make this animal an ideal model for evaluating the effects of lower extremity angioplasty procedures commonly performed to improve limb blood flow artery disease (PAD). Hypothesis: We hypothesized that PET/CT imaging would provide a non-invasive strategy quantifying inflammatory response balloon overdilation injury angioplasty. Methods: Five Yorkshire pigs (weight = 25 kg) underwent right femoral artery. A...