A5025743663- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Aortic Disease and Treatment Approaches
- Tissue Engineering and Regenerative Medicine
- Cardiovascular Conditions and Treatments
- Tracheal and airway disorders
- Coronary Artery Anomalies
- Congenital heart defects research
- Advanced X-ray and CT Imaging
- Aortic aneurysm repair treatments
- Vascular anomalies and interventions
- Mechanical Circulatory Support Devices
- Advanced MRI Techniques and Applications
- Cardiac Structural Anomalies and Repair
- Cardiovascular and Diving-Related Complications
- Synthesis and Reactivity of Heterocycles
- Peripheral Artery Disease Management
- Advanced X-ray Imaging Techniques
- Cyclopropane Reaction Mechanisms
- Cardiac Arrhythmias and Treatments
- Laser-Plasma Interactions and Diagnostics
- Phytochemistry and biological activities of Ficus species
- Congenital Diaphragmatic Hernia Studies
- Bone Tissue Engineering Materials
Nationwide Children's Hospital
2020-2024
University of Toyama
2015-2021
Kobe Children's Hospital
2014-2021
Ryutsu Keizai University
2017
Hyogo Brain and Heart Center
2013
Kobe Rosai Hospital
2011
Abstract Background Tissue-engineered vascular grafts (TEVGs) have the potential to advance surgical management of infants and children requiring congenital heart surgery by creating functional conduits with growth capacity. Methods Herein, we used an integrative computational-experimental approach elucidate natural history neovessel formation in a large animal preclinical model; combining vitro accelerated degradation study mechanical testing, implantation studies vivo imaging histology,...
Background Perfusion deficits contribute to symptom severity, morbidity, and death in peripheral artery disease (PAD); however, no standard method for quantifying absolute measures of skeletal muscle perfusion exists. This study sought preclinically test clinically translate a positron emission tomography (PET) imaging approach using an atherosclerosis‐targeted radionuclide, fluorine‐18‐sodium fluoride ( 18 F‐NaF), quantify PAD. Methods Results Eight Yorkshire pigs underwent unilateral...
Background: The feasibility of synchrotron radiation-based phase-contrast computed tomography (PCCT) for visualization the atrioventricular (AV) conduction axis in human whole heart specimens was tested using four postmortem structurally normal newborn hearts obtained at autopsy. Methods: A PCCT imaging system beamline BL20B2 a SPring-8 radiation facility used. performed with “virtual” slicing three-dimensional reconstructed images. For histological verification, were cut into planes similar...
The importance of ventricular pacing site in pediatric pacemaker therapy has gradually become recognized. We reviewed our experience with a left (LV)-prioritized strategy. METHODS AND RESULTS: Between 2000 and 2012, 60 patients underwent 76 permanent implantations. Eight the 29 reoperations involved lead repositioning for pacing-induced dysfunction. Freedom from failure was 96.3%, 86.8%, 81.0% at 1, 3, 5 years, respectively. independent predictors were age (P=0.026) peak minimal energy...
To visualize and quantify the atrioventricular conduction axis in setting of ventricular septal defect using phase contrast computed tomography.We used SPring-8 synchrotron radiation facility Hyogo prefecture Japan, processing reconstructing data with 3-dimensional software.We studied 8 hearts obtained from patients known to have had defects, aged 6 150 days, a median 24.5 days. None individuals, however, undergone corrective surgery. The penetrating bundle was found at 1.43 mm crest, range...
Popliteal artery entrapment syndrome is recognized as a cause of lower leg claudication in patients younger than 50 years age. We report rare case patient with bilateral popliteal who presented the same symptom 11 after his first experience syndrome. On both occasions, surgery was performed similar manner and free from symptoms surgery. Since diagnosis difficult, early detection important to prevent its progression.
A 58-year-old female presenting with congestive heart failure due to a fistula between an aortic false aneurysm and the superior vena cava (SVC) is described. She had history of Takayasu's arteritis (TA) she undergone valve ascending aorta replacement coronary artery bypass grafting 6 years before. The occurred 1 year after surgery, been conservatively managed. operation revealed that cause was detachment two proximal saphenous vein anastomoses graft. After patient made uneventful recovery....
Adjusting right ventricle-pulmonary artery shunt flow with placement of hemostatic clips in the Norwood operation is a useful technique for precise control pulmonary blood acute postoperative period. This report describes our optimizing metal through left anterior extrapleural approach, which can be performed safely and minimally invasively without sternal reopening. procedure may decrease morbidity contribute to long-term clinical improvement patients undergoing operation.
Although innominate artery transection for compression of the trachea is recently used prevention life-threatening complications (e.g. massive bleeding and obstructive apnoea) in patients with neurological disorders, pre-existing tracheostomy poses a risk mediastinal infection sternotomy. We successfully performed on such patient via left anterior extrapleural approach without sternotomy after confirming anatomical configuration three-dimensional multidetector row computed tomography angiography.
【背景】Fontan症例では静脈圧の上昇による遠隔期のうっ血性肝炎・肝硬変が報告されている．近年，その指標として肝線維化マーカーが測定され始めているが，それらとFontan循環との関連性はいまだ明らかではない．【方法】当院で経過観察されているFontan術後患者（Fontan completion : 1994年3月～2010年7月）で肝線維化マーカー（ヒアルロン酸：HA，レチノール酸結合蛋白：RBP，P-III-P，IV型コラーゲン7S 4C7S，IV型コラーゲン：4Cの5種類）が測定され，かつカテーテル検査（肺動脈圧：PAP，PA index...
Persistent respiratory symptoms often occur after surgical repair of double aortic arch (DAA). Most often, are relatively mild and tend to be self-limited improve with growth. Multidetector computed tomography (MDCT) imaging can used obtain needed anatomic information regarding the potential for extrinsic airway compression is minimally invasive, safe, readily available surgery. We herein report cases two patients persistent therapy a arch. One eventually required aortopexy in order achieve...
Palliative treatment of cyanotic congenital heart disease (CCHD) uses systemic-to-pulmonary conduits, often a modified Blalock-Taussig-Thomas shunt (mBTTs). Expanded polytetrafluoroethylene (ePTFE) mBTTs have associated risks for thrombosis and infection. The Human Acellular Vessel (HAV) (Humacyte, Inc) is decellularized tissue-engineered blood vessel currently in clinical trials adults vascular trauma, peripheral artery disease, end-stage renal requiring hemodialysis. In addition to...
Repair of a postinfarction ventricular septal defect (VSD) is challenging procedure with high risk postoperative residual shunt and subsequent mortality. This retrospective study aimed to assess modified infarct exclusion technique biventricular approach.Nineteen consecutive patients who underwent the for VSD between 2002 2011 were reviewed. A approach (B group: 6 patients) left (L 13 studied by univariate analysis.The overall 30-day mortality was 15.8%, not different two groups (p=0.94)....