A5069467740- Superconducting Materials and Applications
- Superconductivity in MgB2 and Alloys
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Aluminum Alloy Microstructure Properties
- Physics of Superconductivity and Magnetism
- Cardiac and Coronary Surgery Techniques
- Metallurgy and Material Forming
- Aortic Disease and Treatment Approaches
- Cardiac, Anesthesia and Surgical Outcomes
- Metallurgical and Alloy Processes
- Intermetallics and Advanced Alloy Properties
- Microstructure and mechanical properties
- Congenital Heart Disease Studies
- Metal and Thin Film Mechanics
- Particle accelerators and beam dynamics
- Vascular Procedures and Complications
- Aortic aneurysm repair treatments
- Cardiovascular and Diving-Related Complications
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Function and Risk Factors
- Chronic Kidney Disease and Diabetes
- Microstructure and Mechanical Properties of Steels
- Cardiac Arrest and Resuscitation
University of Toyama
2012-2025
Toyama University Hospital
2020-2024
Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital
2019-2023
Kyushu University
1995-2022
Open Evidence
2022
Level (Czechia)
2022
Tokushima University
2011-2017
Tokushima University Hospital
2015-2017
Institute of Biomedical Science
2017
Shinonoi General Hospital
2013-2016
Renal disease is one of the most common and severe complications diabetes mellitus. The hallmark disease, glomerulosclerosis, characterized by an accumulation extracellular matrix in mesangial areas, leading to progressive obliteration vascular spaces. role metabolic derangements mellitus development these lesions incompletely understood. One consequences hyperglycemia formation advanced glycosylation end products (AGEs), which result from a series rearrangements secondary nonenzymatic...
Achieving an optimal balance between thrombosis prevention and bleeding risk during temporary mechanical circulatory support remains a significant clinical challenge. Effective anticoagulation management that ensures device functionality while minimizing major events should have the potential to improve short-term outcomes. Here, we report successful use of nafamostat mesilate (NM) as anticoagulant Impella in two male patients with advanced heart failure cardiogenic shock. NM therapy...
Abstract OBJECTIVES Although there has been rapid development in the field of three-dimensional morphological analyses congenital heart disease, with volume-rendered images providing visualization external vascular anatomy, precise reproduction “Swiss-cheese” ventricular septum is not well established. We created printed models and computer graphics based on multi-slice computed tomography patients complex multiple septal defects for surgical decision planning this difficult cardiac defect....
A H+/organic cation antiporter (multidrug and toxin extrusion 1: MATE1/SLC47A1) plays important roles in the tubular secretion of various clinically cationic drugs such as cimetidine. We have recently found that regulation this transporter greatly affects pharmacokinetic properties vivo. No information is available about regulatory mechanisms for MATE1 gene. In present study, therefore, we examined gene human (h) rat (r) MATE1, focusing on basal expression. deletion analysis suggested...
Glomerulosclerosis is characterized by accumulation of the mesangial extracellular matrix, including type I and V collagen. The processing for collagens in glomeruli may play a critical role development glomerulosclerosis. We examined expression heat shock protein 47 (HSP47), collagen-binding molecular chaperone progressive glomerulosclerosis model. Subtotally nephrectomized rats, unlike sham-operated developed focal segmental Immunological staining demonstrated an increased HSP47 which...
A 50-year-old man who underwent hemodialysis (HD) at local outpatient HD center due to end-stage renal disease (ESRD) was transferred our hospital because of pneumonia. He had severe emaciation and past history congestive heart failure. Presenting symptoms almost consistently involved difficulty in hearing recurrent attacks migraine-like headaches. diagnosed with dilated cardiomyopathy, showing diastolic mechanical dyssynchrony by tissue Doppler echocardiography. On the day death, he...
The specimens were prepared from vacuum-melted alloys, of high purity copper and electrolytic chromium. liquidus eutectic point determind by thermal analysis. temperature is 1074.8° its composition 1.28 wt% determination solid solubbility chromium in was made microscopic observation electrical resistivity measurement. solubility 0.6 at 1050°, 0.4 1000°, 0.25 950°, 0.17 900°, 0.10 840°.
The hepatoportal region is important for glucose sensing; however, the relationship between glucose-sensing system and postprandial rapid phase of insulin response has been unclear. We examined whether a rapid-phase to low amounts intraportal infusion would occur, compared that with intrajugular in conscious rats, assessed this sensing was associated autonomic nerve activity. increases plasma concentration did not differ two infusions at 3 min, but detected only infusion. A sharp observed...
Background:There is a consensus that overactivation of the cardiac sympathetic nervous system (CSN) proportionately increases severity heart failure and accompanied by worse prognosis. Because it unknown whether patients with aortic valve stenosis (AS) have similar CSN activation, we investigated effect transcatheter implantation (TAVI).
This paper describes a monolithically constructed, flexure-hinged translation mechanism suitable for mechanical scanning stages of very high precision. Two piezoelectric stacks are employed to drive the ; one stack pushes whilst other pulls moving platform. push-pull system is effective raising natural frequency stage. The described in this functions as both guide rectilinear motion and amplifier amplify limited output displacement stack. Static dynamic characteristics considered detail,...
The impact of pre-existing atrial fibrillation on the long-term outcome in patients after off-pump coronary revascularisation is not well known. This study aims to determine independent effects preoperative early and late outcomes artery bypass surgery.A total 513 undergoing isolated surgery using approach between 2000 2005 were studied. Twenty-six them (5.1%) had (15 paroxysmal 11 persistent or permanent fibrillation) other 487 normal sinus rhythm. Early compared retrospectively with median...
BACKGROUND:Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by the ossification of soft tissues, primarily ligaments and enthesis. Exuberant osteophyte formation anterior longitudinal ligament spine usually found. Among reported complications cervical osteophyte, dysphagia most frequent symptom, dysphonia rare. CASE REPORT:A 66-year old male was suffering from progressive dysphonia, dysphagia, myelopathy. Anterior osteophytes posterior (OPLL) shown on x-ray computed...
The levels of circulating immune complexes (CIC) were determined using an anti-C3d binding assay in patients with various types glomerulonephritis (GN). It was found that IgG class CIC positive 20% (7/35) idiopathic membranous nephropathy (MN) and 80% (8/10) lupus (LN). Of these patients, IgG4 subclass observed more frequently 29% MN 60% (3/5) minimum change nephrotic syndrome, and, less amounts, 10% (1/10) membranoproliferative GN (MPGN) (2/10) IgA nephropathy. On the other hand, LN showed...
Renal involvement of mixed connective tissue disease (MCTD) shows systemic lupus erythematosus (SLE)-like immune complex glomerulonephritis. The prognosis this condition is generally good. We report the case an elderly female patient with MCTD who developed autoimmune pleurisy and rapidly progressive Myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA) was positive a titer 59.0 EU. Anti-DNA complement levels were normal. biopsy revealed crescentic glomerulonephritis mild mesangial...