Masaya Aoki

ORCID: 0000-0003-3860-5710
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Research Areas
  • Congenital Heart Disease Studies
  • Pulmonary Hypertension Research and Treatments
  • Cardiac Valve Diseases and Treatments
  • Cardiac Structural Anomalies and Repair
  • Infective Endocarditis Diagnosis and Management
  • Aortic Disease and Treatment Approaches
  • Infectious Aortic and Vascular Conditions
  • Congenital Diaphragmatic Hernia Studies
  • Tracheal and airway disorders
  • Coronary Artery Anomalies
  • Aortic aneurysm repair treatments
  • Vascular anomalies and interventions
  • Cardiovascular Function and Risk Factors
  • Reproductive Biology and Fertility
  • Orthopaedic implants and arthroplasty
  • Cardiac tumors and thrombi
  • Reproductive System and Pregnancy
  • Total Knee Arthroplasty Outcomes
  • Cardiovascular and Diving-Related Complications
  • Parvovirus B19 Infection Studies
  • Kawasaki Disease and Coronary Complications
  • Opioid Use Disorder Treatment
  • Surgical site infection prevention
  • Abdominal vascular conditions and treatments
  • Enhanced Recovery After Surgery

University of Tsukuba
2024-2025

University of Toyama
2013-2025

Kagoshima University
2023-2024

Toyama University Hospital
2023

Tokyo Medical University
2014-2015

Hyogo Brain and Heart Center
2013

Saiseikai Shimonoseki General Hospital
1990

Abstract OBJECTIVES Intestinal ischaemia–reperfusion injury induced by cardiopulmonary bypass causes intestinal epithelial barrier dysfunction, leading to dysbiosis and bacterial translocation. We conducted a randomized prospective study with 2 objectives: (i) investigate dysfunction translocation changes in the gut microbiota (ii) verify whether probiotics can improve these conditions. METHODS Between 2019 2020, patients 0–15 years old scheduled undergo cardiac surgery using were enrolled...

10.1093/ejcts/ezae152 article EN European Journal of Cardio-Thoracic Surgery 2024-03-29

Abstract A limited number of female germ cells support reproduction in many mammals. The follicle, composed oocytes and supporting granulosa cells, forms the basis oogenesis. Crosstalk between is essential for formation, dormancy, re-awakening, maturation oocytes. oocyte expresses c-KIT growth differentiation factor-9 (GDF-9), which are major factors this crosstalk. downstream signalling pathways GDF-9 have been well-documented; however, their intra-oocyte trafficking pathway remains...

10.1038/s41420-025-02291-5 article EN cc-by Cell Death Discovery 2025-01-20

Abstract OBJECTIVES Although there has been rapid development in the field of three-dimensional morphological analyses congenital heart disease, with volume-rendered images providing visualization external vascular anatomy, precise reproduction “Swiss-cheese” ventricular septum is not well established. We created printed models and computer graphics based on multi-slice computed tomography patients complex multiple septal defects for surgical decision planning this difficult cardiac defect....

10.1093/ejcts/ezaf080 article EN European Journal of Cardio-Thoracic Surgery 2025-03-08

The values of hip rotation center (HRC) and femoral offset (FO) evaluated according to Caucasian anatomical landmarks have been regarded as a useful reference also for Japanese patients in total arthroplasty (THA). In strict sense, however, since there can be racial differences among their morphologies, it is clinically important reconsider those parameters the Japanese. present study, order investigate correlations pelvic morphometric parameters, frontal radiographs were taken from 98...

10.1155/2015/610763 article EN cc-by BioMed Research International 2015-01-01

Carney complex is a rare syndrome caused by genetic mutation leading to multiple endocrine abnormalities and variety of tumors. Here, we report case diagnosed due recurrent myxomas in the right atrium patient 16 years after resection primary left atrial myxoma. Surgical excision was performed for tumors under cardiopulmonary bypass. The remained complication-free surgery discharged on 14th day. He scheduled continue echocardiographic follow-up periodic systemic review an endocrinologist....

10.1007/s11748-021-01719-w article EN cc-by General Thoracic and Cardiovascular Surgery 2021-10-12

Our goal was to evaluate whether endothlin-1 (ET-1) plays an important role in the Fontan circulation.Thirteen patients with single-ventricle physiology (Glenn circulation, n = 7; 6) were evaluated using lung histopathological and immunohistochemical studies then compared normal autopsied controls without congenital heart disease (n 13). We medial thickness of small pulmonary arteries. For 10 these patients, quantitative real-time polymerase chain reaction analyses ET-1, endothelin receptors...

10.1093/icvts/ivx378 article EN Interactive Cardiovascular and Thoracic Surgery 2017-11-02

<title>Abstract</title> A limited number of female germ cells support reproduction in many mammals. The follicle, composed oocytes and supporting granulosa cells, forms the basis oogenesis. Crosstalk between is essential for formation, dormancy, re-awakening, maturation oocytes. oocyte expresses c-KIT growth differentiation factor-9 (GDF-9), which are major factors this crosstalk. downstream signallingpathways GDF-9 have been well-documented; however, their intra-oocyte trafficking pathway...

10.21203/rs.3.rs-5106937/v1 preprint EN cc-by Research Square (Research Square) 2024-11-14

Acute aortic occlusion is a catastrophic event requiring early recognition and intervention. The patient was diagnosed type B dissection. He became anuric on the sixth day of illness femoral artery pulse not palpable. Therefore conveyed to our hospital. During transfer, his blood pressure suddenly elevated later he in cardiopulmonary arrest. After resuscitation, heart resumed beating several minutes. dynamic obstruction regarded as cause cardiac A thoracic endovascular repair performed...

10.3400/avd.cr.15-00028 article EN Annals of Vascular Diseases 2015-01-01

Lymphangioma is a relatively rare benign congenital malformation composed of dilated cystic lymphatic vessels; however, its occurrence in adults and manifestation as mediastinal lymphangioma are even rarer. In general, the incidence lymphangiomas has been reported to range from 0.01 4.5% all tumors. Mediastinal tend increase size can sometimes stretch phrenic nerve that present mediastinum, resulting palsy. Dynamic digital radiography (DDR) allows for quantitative evaluation over time...

10.1186/s44215-023-00044-3 article EN cc-by General Thoracic and Cardiovascular Surgery Cases 2023-06-13

Abstract The diversion of the inferior vena cava into left atrium after surgical atrial septal defect closure is a fatal complication. Cases with no rim should be treated this complication in mind.

10.1002/ccr3.4618 article EN cc-by Clinical Case Reports 2021-08-01

Abstract Annular abscess is a serious complication of infective endocarditis, which often requires complex surgery and has very high post-operative mortality rate. The Konno procedure involves valve annuloplasty for narrow aortic annulus or left ventricular outflow tract stenosis in children; it also performed various cardiac conditions adults. Here, we report case the patient with an annular extending into interventricular septum (IVS). A 58-year-old man who presented to our hospital fever...

10.1093/jscr/rjab428 article EN cc-by Journal of Surgical Case Reports 2021-09-01

症例1は78歳,男性.心窩部痛を主訴に来院.右下腹部に筋性防御,採血でCEAが高値.腹部X線,腹部CT所見で腹腔内遊離ガス像はないが,腸間膜内に異常なガス像があり,癌合併腹膜炎として緊急手術施行.上行結腸癌と腸間膜内に糞便を認め,右半結腸切除を施行.標本は上行結腸に1型の腫瘍と,その口側の腸間膜側に穿通があり,その粘膜には虚血性変化を認めた.症例2は73歳,男性.腹痛にて当院に救急搬送される.腹部CT検査で腸間膜内に異常ガス像を認め,上行結腸間膜穿通と診断,緊急手術施行.腸間膜内に多量の便塊と上行結腸癌を認め,右半結腸切除を施行.標本は上行結腸に3型の腫瘍と口側の腸間膜側に穿通部を認めた.病理では穿通部に循環障害を指摘された.いずれも比較的順調に経過し,退院した.本症は稀な腸間膜穿通を合併した上行結腸癌だが,診断には腹部CT検査が有用であり,緊急手術で一期的吻合を行い救命しえた.

10.3919/jjsa.71.771 article JA Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 2010-01-01

梅毒性大動脈炎(syphilitic aortitis : SA)は現在では遭遇することが稀な疾患である.今回われわれはSAに起因する大動脈弁輪拡張症(annuloaortic ectasia AAE),大動脈弁閉鎖不全症(aortic regurgitation AR)に右冠動脈(right coronary artery RCA)入口部狭窄を併発した症例に対し,modified Bentall手術および右内胸動脈を使用した冠動脈バイパス術を施行し良好な成績を得たので報告する.症例は48歳,男性.労作時易疲労感,夜間呼吸困難のため救急搬送され,精査の結果Sellers III度のAR, AAEを指摘された.その際の血清学的検査でTP抗体定量28.4 S/CO,RPR定量>20 R.Uと梅毒の現行感染が明らかとなった.CT検査では大動脈基部55 mm,上行大動脈60...

10.4326/jjcvs.46.255 article JA Japanese Journal of Cardiovascular Surgery 2017-01-01

This study was performed for a better understanding of the pharmacokinetics sildenafil (SIL) and N-desmethyl (DMS) in 13 children treated intensive care unit (ICU). Blood samples were taken periodically after first oral administration SIL (0.5 mg/kg). Plasma concentrations analyzed by tandem LC/MS. Of patients, apparent peaks plasma concentration observed four with other nine patients showing reduced or delayed drug absorption SIL. The maximum varied range from 7.8 to 101.0 ng/mL. parent...

10.1248/bpb.b20-00614 article EN Biological and Pharmaceutical Bulletin 2020-10-01

Abstract A coronary artery fistula is a rare condition caused by abnormal embryological development. Although most cases are asymptomatic, in some, the large shunt volume and myocardial ischemia due to steal phenomenon require surgical treatment. We present case of 40-year-old woman who presented with angina on exertion. Enhanced computed tomography showed giant right (RCA) aneurysm an RCA-to-right atrium fistula. Because presence symptoms fistulous tract, patient was considered candidate....

10.1093/jscr/rjab286 article EN cc-by Journal of Surgical Case Reports 2021-06-17
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