A5035564927- Cardiac Valve Diseases and Treatments
- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Cardiac, Anesthesia and Surgical Outcomes
- Infective Endocarditis Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Vascular Procedures and Complications
- Infectious Aortic and Vascular Conditions
- Mesenchymal stem cell research
- Tracheal and airway disorders
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiovascular and Diving-Related Complications
- Tissue Engineering and Regenerative Medicine
- Aortic aneurysm repair treatments
- Congenital heart defects research
- Surgical site infection prevention
- Venous Thromboembolism Diagnosis and Management
- Hemostasis and retained surgical items
- Cardiac tumors and thrombi
- bioluminescence and chemiluminescence research
- Abdominal vascular conditions and treatments
- Anatomy and Medical Technology
University of Toyama
2011-2025
Shinonoi General Hospital
2019-2021
Toyama Prefectural Central Hospital
2009
University of Yamanashi
1999
Achieving an optimal balance between thrombosis prevention and bleeding risk during temporary mechanical circulatory support remains a significant clinical challenge. Effective anticoagulation management that ensures device functionality while minimizing major events should have the potential to improve short-term outcomes. Here, we report successful use of nafamostat mesilate (NM) as anticoagulant Impella in two male patients with advanced heart failure cardiogenic shock. NM therapy...
Abstract OBJECTIVES Although there has been rapid development in the field of three-dimensional morphological analyses congenital heart disease, with volume-rendered images providing visualization external vascular anatomy, precise reproduction “Swiss-cheese” ventricular septum is not well established. We created printed models and computer graphics based on multi-slice computed tomography patients complex multiple septal defects for surgical decision planning this difficult cardiac defect....
Regenerative therapy is a new strategy for the end-stage heart failure; however, ideal cell source has not yet been established this therapy. We expected that amnion might be an cardiac regenerative and differentiation potency of human mesenchymal cells (hAMCs) could improved by overexpression Oct4, key factor maintains undifferentiated state. A plasmid vector was made insertion Oct4 open reading frame (ORF) under control cytomegalovirus (CMV) promoter (pCMV-hOct4) transfected into hAMCs...
Adult cardiomyocytes have little ability to regenerate, thus cardiac regeneration therapy represents a potential method for treating severe heart failure. Human amniotic mesenchymal cells (hAMCs) the be useful cell source therapy. We attempted isolate stem from hAMCs and differentiate them into cardiomyocytes. Nanog promoter-Cre plasmid cytomegalovirus (CMV) promoter-loxP-STOP-loxP-Red-puro(r) were co-transfected immortalized (iHAMs). Nanog-positive iHAMs treated with 5-azacytidine (5-aza),...
This study is the first case report of treatment methicillin-resistant Staphylococcus aureus (MRSA) mediastinitis using therapeutic drug monitoring serum and wound exudate concentrations linezolid in a renal dysfunction patient. In present study, trough concentration was maintained between 2 7 μg/mL. Therapeutic dosage adjustments may be especially useful patients with severe MRSA infection.
Background:There is a consensus that overactivation of the cardiac sympathetic nervous system (CSN) proportionately increases severity heart failure and accompanied by worse prognosis. Because it unknown whether patients with aortic valve stenosis (AS) have similar CSN activation, we investigated effect transcatheter implantation (TAVI).
Papillary muscle rupture is a lethal complication of after acute myocardial infarction. We report the successful surgical management complete anterolateral papillary associated with cardiogenic shock in an 80-year-old woman. The patient was admitted sudden onset chest pain and dyspnea. After hemodynamics deteriorated rapidly, she intubated intra-aortic balloon pump started immediately. Transthoracic echocardiography revealed severe mitral regurgitation due to lateral Coronary angiography...
Right aortic arch with aberrant left subclavian artery and Kommerell diverticulum are rare anomalies. A 42-year-old man was referred sudden-onset chest pain. Enhanced computed tomography (CT) showed a right early thrombosed acute type dissection an arising from diverticulum. Medical therapy instituted; however, follow-up CT revealed ulcer-like projection. The patient managed two-stage hybrid procedure comprising total replacement endovascular repair experienced no postoperative...
The prognosis of uncorrected aortic coarctation is poor due to development heart failure. We performed an on-pump beating extraanatomical ascending-descending bypass using a positioner in adult with complicated by severe left ventricular hypertrophy. A 51-year-old woman was referred hypertension. Computed tomography demonstrated distal arch narrowing. Coarctation the aorta diagnosed. posterior pericardial via median sternotomy from ascending descending positioner. Her postoperative course...
【背景】Fontan症例では静脈圧の上昇による遠隔期のうっ血性肝炎・肝硬変が報告されている．近年，その指標として肝線維化マーカーが測定され始めているが，それらとFontan循環との関連性はいまだ明らかではない．【方法】当院で経過観察されているFontan術後患者（Fontan completion : 1994年3月～2010年7月）で肝線維化マーカー（ヒアルロン酸：HA，レチノール酸結合蛋白：RBP，P-III-P，IV型コラーゲン7S 4C7S，IV型コラーゲン：4Cの5種類）が測定され，かつカテーテル検査（肺動脈圧：PAP，PA index...
Introduction: As a result of the increasing age patients requiring myocardial revascularization for ischemic heart disease, preexisting atrial fibrillation (AF) is among who undergo coronary artery bypass grafting (CABG). However impact concomitant AF surgery on early outcomes in after CABG remains unknown. The aim this study was to assess influences risk mortality and morbidity CABG. Methods: By using Japan Adult Cardiovascular Surgery Database (JACVSD), with preoperative underwent were...
We report our experience with aortic valve replacement in a patient severe stenosis who had self-reported allergies to multiple metals. The was 74-year-old man. He developed palmoplantar pustulosis after using dental prosthesis, and patch test revealed reactions several metals; therefore, he diagnosed systemic metal allergy. His condition progressed stenosis, bioprosthetic planned. Avalus (Medtronic, Minneapolis, MN, USA) selected for replacement, since the reported having While most devices...
Abstract Annular abscess is a serious complication of infective endocarditis, which often requires complex surgery and has very high post-operative mortality rate. The Konno procedure involves valve annuloplasty for narrow aortic annulus or left ventricular outflow tract stenosis in children; it also performed various cardiac conditions adults. Here, we report case the patient with an annular extending into interventricular septum (IVS). A 58-year-old man who presented to our hospital fever...
梅毒性大動脈炎（syphilitic aortitis : SA）は現在では遭遇することが稀な疾患である．今回われわれはSAに起因する大動脈弁輪拡張症（annuloaortic ectasia AAE），大動脈弁閉鎖不全症（aortic regurgitation AR）に右冠動脈（right coronary artery RCA）入口部狭窄を併発した症例に対し，modified Bentall手術および右内胸動脈を使用した冠動脈バイパス術を施行し良好な成績を得たので報告する．症例は48歳，男性．労作時易疲労感，夜間呼吸困難のため救急搬送され，精査の結果Sellers III度のAR, AAEを指摘された．その際の血清学的検査でTP抗体定量28.4 S/CO，RPR定量＞20 R.Uと梅毒の現行感染が明らかとなった．CT検査では大動脈基部55 mm，上行大動脈60...